International Journal of Developmental Biology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Understanding megasporogenesis through model plants: contemporary evidence and future insights
Int J Dev Biol. 2024;68(1):9-17. doi: 10.1387/ijdb.230222mk.ABSTRACTThe megasporangium serves as a model system for understanding the concept of individual cell identity, and cell-to-cell communication in angiosperms. As development of the ovule progresses, three distinct layers, the epidermal (L1), the subepidermal or the hypodermal (L2) and the innermost layers (L3) are formed along the MMC (megaspore mother cell). The MMC, which is the primary female germline cell, is initiated as a single subepidermal cell amongst several somatic cells. MMC development is governed by various regulatory pathways involving intercellular ...
Source: International Journal of Developmental Biology - April 9, 2024 Category: Biology Authors: Inderdeep Kaur Renu Kathpalia Monika Koul Source Type: research

Disrupted odontoblast differentiation and dentin dysplasia in < em > Epiprofin < /em > -deficient mice
Int J Dev Biol. 2024;68(1):19-24. doi: 10.1387/ijdb.240029lj.ABSTRACTTooth formation is a process tightly regulated by reciprocal interactions between epithelial and mesenchymal tissues. These epithelial-mesenchyme interactions regulate the expression of target genes via transcription factors. Among the regulatory elements governing this process, Epiprofin/Sp6 is a zinc finger transcription factor which is expressed in the embryonic dental epithelium and in differentiating pre-odontoblasts. Epiprofin knockout (Epfn-/-) mice present severe dental abnormalities, such as supernumerary teeth and enamel hypoplasia. Here, we des...
Source: International Journal of Developmental Biology - April 9, 2024 Category: Biology Authors: Lucia Jim énez-Rojo Susana de Vega Gaskon Ibarretxe Takashi Nakamura Fernando J Unda Source Type: research

Enhancement of neural crest formation by mechanical force in < em > Xenopus < /em > development
In this study, with an aspiration assay and atomic force microscopy, we have demonstrated that tension on ectodermal cells decreases laterally from the midline in Xenopus early neurula. Ectopically applied force laterally expanded the neural crest (NC) region, a derivative of the NPB, whereas force relaxation suppressed it. Furthermore, force application activated both the FGF and Wnt pathways, which are required for NC formation during neuroectodermal patterning. Taken together, mechanical force is necessary for NC formation in order to regulate signaling pathways. Furthermore, molecular signals specify the NP and generat...
Source: International Journal of Developmental Biology - April 9, 2024 Category: Biology Authors: Toki Kaneshima Masaki Ogawa Takayoshi Yamamoto Yosuke Tsuboyama Yuki Miyata Takahiro Kotani Takaharu Okajima Tatsuo Michiue Source Type: research

Developmental relationship between junctional epithelium and epithelial rests of Malassez
Int J Dev Biol. 2024;68(1):39-45. doi: 10.1387/ijdb.230243sl.ABSTRACTKeratin 17 (K17) is thought to be a candidate target gene for regulation by Lymphoid Enhancer Factor-1 (Lef-1). K17 is a marker that distinguishes junctional epithelium (JE) from epithelial rests of Malassez (ERM). However, the relationship of Lef-1 to K17 is not clear in this context. Moreover, the expression of other keratins such as K5, K6, K7 and K16 is not reported. Therefore, the aim of our study was to assay the expression of K5, K6, K7, K14, K16, K17 and Lef-1 in postnatal developing teeth, and clarify the corresponding immunophenotypes of the JE ...
Source: International Journal of Developmental Biology - April 9, 2024 Category: Biology Authors: Shubo Li Shufang Li Mingguo Cao Source Type: research