Diagnostic stability in children and adolescents with bipolar disorder, a nationwide register-based study
Diagnostic stability of bipolar disorder (BD) in children and adolescents, beyond the first contact has been investigated sparsely. The aim of this study was to investigate the diagnostic stability of BD in ch... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - May 6, 2020 Category: Psychiatry Authors: Mathilde Frahm Laursen, Rasmus W. Licht, Christoph U. Correll, Tobias Kallehauge, Ann-Eva Christensen, Maria Rodrigo-Domingo and Ren é Ernst Nielsen Tags: Research Source Type: research

The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective registry
To compare illness characteristics, treatment history, response and durability, and suicidality scores over a 5-year period in patients with treatment-resistant bipolar depression participating in a prospectiv... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - May 2, 2020 Category: Psychiatry Authors: R. Hamish McAllister-Williams, Soraia Sousa, Arun Kumar, Teresa Greco, Mark T. Bunker, Scott T. Aaronson, Charles R. Conway and A. John Rush Tags: Research Source Type: research

Pre-pubertal bipolar disorder: origins and current status of the controversy
Evidence from epidemiological, clinical and high-risk studies has established that the peak period of risk for onset of bipolar disorder spans late adolescence and early adulthood. However, the proposal of the... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - April 20, 2020 Category: Psychiatry Authors: A. Duffy, G. Carlson, B. Dubicka and M. H. J. Hillegers Tags: Review Source Type: research

Reflections on: "The diagnosis of bipolar disorder in pre-pubertal children —what was the controversy about and what did we learn as a result?"
It can be argued that the controversy over paediatric bipolar disorder has been useful in highlighting the issue of bipolar disorder in youths generally. Arising out of this controversy is the recognition that... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - April 20, 2020 Category: Psychiatry Authors: Anthony James Tags: Letter to the Editor Source Type: research

Prepubertal bipolar disorder: a diagnostic quandary?
(Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - April 20, 2020 Category: Psychiatry Authors: Gin S. Malhi and Erica Bell Tags: Letter to the Editor Source Type: research

Mixed mood states and emotion-related urgency in bipolar spectrum disorders: a call for greater investigation
(Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - March 5, 2020 Category: Psychiatry Authors: Jennie A. Jaggers and June Gruber Tags: Letter to the Editor Source Type: research

Cortisol levels in unmedicated patients with unipolar and bipolar major depression using hair and saliva specimens
Differentiating between unipolar and bipolar depression can be clinically challenging, especially at first presentation. Patterns of cortisol secretion could aid diagnostic discrimination in affective disorder... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - March 5, 2020 Category: Psychiatry Authors: Andr és Herane-Vives, Danilo Arnone, Valeria de Angel, Andrew Papadopoulos, Toby Wise, Luis Alameda, Kia-Chong Chua, Allan H. Young and Anthony J. Cleare Tags: Research Source Type: research

Role of child maltreatment and gender for bipolar symptoms in young adults
Child maltreatment has been shown to be associated with a wide range of mental disorders, including bipolar disorders. In this 2-year follow-up study, recollections of emotional, physical and sexual abuse were... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - March 2, 2020 Category: Psychiatry Authors: Ida S. Haussleiter, Eva Neumann, Sandra Lorek, Bianca Ueberberg and Georg Juckel Tags: Research Source Type: research

Combination of dextromethorphan and memantine in treating bipolar spectrum disorder: a 12-week double-blind randomized clinical trial
The aim of this study is to determine whether adding combination of agents with anti-inflammatory and neurotrophic effects is more efficacious than mood stabilizer alone in improving clinical symptoms, plasma ... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - March 2, 2020 Category: Psychiatry Authors: Sheng-Yu Lee, Tzu-Yun Wang, Shiou-Lan Chen, Yun-Hsuan Chang, Po-See Chen, San-Yuan Huang, Nian-Sheng Tzeng, Liang-Jen Wang, I-Hui Lee, Kao-Ching Chen, Yen-Kuang Yang, Jau-Shyong Hong and Ru-Band Lu Tags: Research Source Type: research

The role of environmental stress and DNA methylation in the longitudinal course of bipolar disorder
Stressful life events influence the course of affective disorders, however, the mechanisms by which they bring about phenotypic change are not entirely known. (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - February 12, 2020 Category: Psychiatry Authors: Ashley L. Comes, Darina Czamara, Kristina Adorjan, Heike Anderson-Schmidt, Till F. M. Andlauer, Monika Budde, Katrin Gade, Maria Hake, Janos L. Kalman, Sergi Papiol, Daniela Reich-Erkelenz, Farah Kl öhn-Saghatolislam, Sabrina K. Schaupp, Eva C. Schulte, Tags: Research Source Type: research

A comprehensive assessment of personality traits and psychosocial functioning in parents with bipolar disorder and their intimate partners
Individuals with bipolar disorder (BD) often possess maladaptive traits and present with various difficulties in psychosocial functioning. However, little is known about the intimate partners of adults with bi... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - February 10, 2020 Category: Psychiatry Authors: Lisa Serravalle, Vanessa Iacono, Sheilagh Hodgins and Mark A. Ellenbogen Tags: Research Source Type: research

Executive functioning but not IQ or illness severity predicts occupational status in bipolar disorder
Bipolar disorder is associated with significant functional deficits including occupational functioning. Despite the high rates of unemployment and sick leave in the patient population, only a limited number of... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - February 7, 2020 Category: Psychiatry Authors: Julia Drakopoulos, Timea Sparding, Caitlin Clements, Erik P ålsson and Mikael Landén Tags: Research Source Type: research

An integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder
Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown. (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - February 3, 2020 Category: Psychiatry Authors: Xin Qi, Yan Wen, Ping Li, Chujun Liang, Bolun Cheng, Mei Ma, Shiqiang Cheng, Lu Zhang, Li Liu, Om Prakash Kafle and Feng Zhang Tags: Research Source Type: research

The existential crisis of bipolar II disorder
The issue of categorical vs. dimensional classification of bipolar disorder continues to generate controversy as it has for generations. Despite the evidence that no psychiatric disorder has discrete boundarie... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - January 28, 2020 Category: Psychiatry Authors: Michael Gitlin and Gin S. Malhi Tags: Review Source Type: research

Bipolar disorders in ICD-11: current status and strengths
The Clinical descriptions and diagnostic guidelines for the ICD-11 Classification of mental and behavioural disorders should soon be finalized. To measure their potential impact, the new proposed definitions o... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - January 20, 2020 Category: Psychiatry Authors: Jules Angst, Vladeta Ajdacic-Gross and Wulf R össler Tags: Short Communication Source Type: research