Long-term outcomes of patients supported with extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis
ConclusionSurvivors of ECMO for ARDS experience significant disability in multiple domains. Further studies are needed to examine the effect of ECMO on long-term outcomes of patients compared to CMV. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 10, 2024 Category: Intensive Care Source Type: research
Immune-mediated thrombotic thrombocytopenic purpura: don ’t miss the boat
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 9, 2024 Category: Intensive Care Source Type: research
How environmental impact is considered in economic evaluations of critical care: a scoping review
ConclusionsHealth economic evaluations of critical care have not yet incorporated environmental impact into their assessments, and few life cycle assessments exist that are specific to critical care therapies and treatments. Guidelines and standardisation regarding environmental data collection and reporting in health care are needed to support further research in the field. In the meantime, those planning health economic evaluations should include a process-based life cycle assessment to establish key environmental impacts specific to critical care. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 8, 2024 Category: Intensive Care Source Type: research
Contemporary management of major haemorrhage in critical care
AbstractHaemorrhagic shock is frequent in critical care settings and responsible for a high mortality rate due to multiple organ dysfunction and coagulopathy. The management of critically ill patients with bleeding and shock is complex, and treatment of these patients must be rapid and definitive. The administration of large volumes of blood components leads to major physiological alterations which must be mitigated during and after bleeding. Early recognition of bleeding and coagulopathy, understanding the underlying pathophysiology related to specific disease states, and the development of individualised management proto...
Source: Intensive Care Medicine - January 8, 2024 Category: Intensive Care Source Type: research
Angiotensin II
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 8, 2024 Category: Intensive Care Source Type: research
What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 8, 2024 Category: Intensive Care Source Type: research
Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL)
ConclusionAmong critically ill patients with SA-AKI, ilofotase alfa did not improve day 28 survival. There may, however, be reduced MAKE90 events. No safety concerns were identified. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 3, 2024 Category: Intensive Care Source Type: research
The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations
ConclusionThe specificity of the ERC-ESICM-recommended EEG patterns for predicting poor outcome after CA exceeds 90% but is lower than in previous studies, suggesting that large-scale implementation may reduce their accuracy. Combining HMEP with an unreactive EEG background significantly improved specificity. As in other prognostication studies, a self-fulfilling prophecy bias may have contributed to observed results. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 3, 2024 Category: Intensive Care Source Type: research
Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium
ConclusionsIn acutely admitted adult ICU patients with delirium, haloperidol treatment reduced mortality at 1-year follow-up, but did not statistically significantly improve HRQoL. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 3, 2024 Category: Intensive Care Source Type: research
Venous thromboembolism in critically ill adult patients with hematologic malignancy: a population-based cohort study
ConclusionAmong patients with hematologic malignancy, critical illness and certain baseline characteristics were associated with a higher incidence of VTE. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 3, 2024 Category: Intensive Care Source Type: research
October 7th 2023 attacks in Israel: frontline experience of a single tertiary center
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 3, 2024 Category: Intensive Care Source Type: research
Ten reasons for the presence of pharmacy professionals in the intensive care unit
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 3, 2024 Category: Intensive Care Source Type: research
Ventilator induced lung injury: a case for a larger umbrella?
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 3, 2024 Category: Intensive Care Source Type: research
Selective decontamination of the digestive tract: it ’s all in your mind!
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - December 21, 2023 Category: Intensive Care Source Type: research
Status epilepticus in the ICU
AbstractStatus epilepticus (SE) is a common medical emergency associated with significant morbidity and mortality. Management that follows published guidelines is best suited to improve outcomes, with the most severe cases frequently being managed in the intensive care unit (ICU). Diagnosis of convulsive SE can be made without electroencephalography (EEG), but EEG is required to reliably diagnose nonconvulsive SE. Rapidly narrowing down underlying causes for SE is crucial, as this may guide additional management steps. Causes may range from underlying epilepsy to acute brain injuries such as trauma, cardiac arrest, stroke,...
Source: Intensive Care Medicine - December 20, 2023 Category: Intensive Care Source Type: research
