Validation of a new data-driven SLOSR ICU efficiency measure compared to the traditional SRU
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - November 3, 2023 Category: Intensive Care Source Type: research

Anticoagulation in the ICU: a future for contact pathway inhibition?
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - November 1, 2023 Category: Intensive Care Source Type: research

Inflammatory subphenotypes in patients at risk of ARDS: evidence from the LIPS-A trial
ConclusionHyper- and non-hyper-inflammatory subphenotypes may precede ARDS development, remain identifiable over time, and can be identified upon presentation to the emergency department. A hyper-inflammatory subphenotype predicts worse outcomes. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 31, 2023 Category: Intensive Care Source Type: research

A global perspective on acute kidney injury after major surgery: much needed insights and sobering results
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 31, 2023 Category: Intensive Care Source Type: research

SHAP model explainability in ECMO –PAL mortality prediction: a critical analysis
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 31, 2023 Category: Intensive Care Source Type: research

SHAP Model Explainability in ECMO – PAL mortality prediction: A Critical Analysis. Author’s reply
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 31, 2023 Category: Intensive Care Source Type: research

D-dimer trends in ECMO patients: don ’t shoot the messenger
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 31, 2023 Category: Intensive Care Source Type: research

The EAS(E)IX of predicting sepsis after allogeneic hematopoietic cell transplantation
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 24, 2023 Category: Intensive Care Source Type: research

Effects of an online information tool on post-traumatic stress disorder in relatives of intensive care unit patients: a multicenter double-blind, randomized, placebo-controlled trial (ICU-Families-Study)
ConclusionFamily members of critically ill patients often have significant PTSD symptoms and online information on critical illness did not result in reduced PTSD symptoms. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 23, 2023 Category: Intensive Care Source Type: research

Magnesium sulphate in patients with thrombotic thrombocytopenic purpura (MAGMAT): a randomised, double-blind, superiority trial
ConclusionAmong patients with TTP, the addition of magnesium sulphate to the standard of care did not result in a significant improvement in time to platelet normalisation. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 23, 2023 Category: Intensive Care Source Type: research

Management of supraventricular arrhythmias in the intensive care unit: a step in the right direction
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 23, 2023 Category: Intensive Care Source Type: research

Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes
ConclusionAmong critically ill patients with sepsis, subtype strategies using clinical, biomarker, and transcriptomic data do not identify comparable patient populations and are likely to reflect disparate clinical characteristics and underlying biology. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 18, 2023 Category: Intensive Care Source Type: research

Racial and ethnic minority participants in clinical trials of acute respiratory distress syndrome
ConclusionRepresentation of racial and ethnic minority participants in ARDS trials from North America, published between 2000 and 2019, did not change over time. Black and Hispanic participants with ARDS may have similar mortality as White participants within trials. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 17, 2023 Category: Intensive Care Source Type: research

Size does matter. Sustainable choice of intravenous bags
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 16, 2023 Category: Intensive Care Source Type: research

Association of language concordance and restraint use in adults receiving mechanical ventilation
ConclusionsWe identified a twofold reduction in the odds of restraint use among mechanically ventilated patients for language concordant nurse –patient dyads. Ensuring nurse–patient language concordance may improve ICU delirium, agitation, and restraint use. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 16, 2023 Category: Intensive Care Source Type: research