Management of supraventricular arrhythmias in the intensive care unit: a step in the right direction
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 23, 2023 Category: Intensive Care Source Type: research

Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes
ConclusionAmong critically ill patients with sepsis, subtype strategies using clinical, biomarker, and transcriptomic data do not identify comparable patient populations and are likely to reflect disparate clinical characteristics and underlying biology. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 18, 2023 Category: Intensive Care Source Type: research

Racial and ethnic minority participants in clinical trials of acute respiratory distress syndrome
ConclusionRepresentation of racial and ethnic minority participants in ARDS trials from North America, published between 2000 and 2019, did not change over time. Black and Hispanic participants with ARDS may have similar mortality as White participants within trials. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 17, 2023 Category: Intensive Care Source Type: research

Size does matter. Sustainable choice of intravenous bags
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 16, 2023 Category: Intensive Care Source Type: research

Association of language concordance and restraint use in adults receiving mechanical ventilation
ConclusionsWe identified a twofold reduction in the odds of restraint use among mechanically ventilated patients for language concordant nurse –patient dyads. Ensuring nurse–patient language concordance may improve ICU delirium, agitation, and restraint use. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 16, 2023 Category: Intensive Care Source Type: research

Transitioning to reality: the diary of an ARDS survivor
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 16, 2023 Category: Intensive Care Source Type: research

Putting your trust in ICU clinical trials: the journal ’s role
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 16, 2023 Category: Intensive Care Source Type: research

Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial
ConclusionsIn critically ill patients with severe AKI, initiation of CRRT, as compared to IHD, was associated with a significant reduction in the composite outcome of death or RRT dependence at 90-days. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 10, 2023 Category: Intensive Care Source Type: research

Self-reported symptoms experienced by intensive care unit patients: a prospective observational multicenter study
ConclusionsSelf-reporting ICU patients experienced a high and consistent symptom burden across seven days. Certain variables were associated with the degree of symptom intensity, but further research is required to better understand these associations. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 9, 2023 Category: Intensive Care Source Type: research

Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)
ConclusionThrombocytopenia occurred in 43% of critically ill patients and was associated with worse outcomes including increased mortality. Platelet transfusions were given to 23% of patients with thrombocytopenia and most were prophylactic. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 9, 2023 Category: Intensive Care Source Type: research

The impact of religion on changes in end-of-life practices in European intensive care units: a comparative analysis over 16  years
ConclusionsChanges in end-of-life practices observed over 16  years appear unrelated to religious affiliations of ICU patients or their treating physicians, but the effects of religiosity and/or culture could not be assessed. Shorter time until decision in the ICU and increased numbers of patient and family discussions may indicate increased awareness of the importance of end-of-life decision-making in the ICU. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 9, 2023 Category: Intensive Care Source Type: research

Rose ’s second life after ICU: a tale of post-traumatic growth
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 9, 2023 Category: Intensive Care Source Type: research

A microcirculation-guided trial: never trying is worse than failing
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 9, 2023 Category: Intensive Care Source Type: research

Age and associated outcomes among patients receiving venoarterial extracorporeal membrane oxygenation –analysis of the Extracorporeal Life Support Organization registry
ConclusionsAmong patients receiving V-A ECMO for cardiogenic shock, increasing age is strongly associated with increasing odds of death and complications, and this association emerges as early as 40  years of age. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 4, 2023 Category: Intensive Care Source Type: research

Exploring disease axes as an alternative to distinct clusters for characterizing sepsis heterogeneity
ConclusionsCluster analysis of sepsis patients across various cohorts showed modest reproducibility. Sepsis heterogeneity is better characterized through continuous disease axes that coexist to varying degrees within the same individual instead of mutually exclusive subtypes. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - October 4, 2023 Category: Intensive Care Source Type: research