Mobile telephony radiation exerts genotoxic action and significantly enhances the effects of gamma radiation in human cells
Gen Physiol Biophys. 2023 Dec 8. doi: 10.4149/gpb_2023036. Online ahead of print.ABSTRACTI previously reported induction of chromosomal damage in human peripheral blood lymphocytes (HPBLs) induced by: a) Mobile telephony (MT) electromagnetic fields (EMFs)/electromagnetic radiation (EMR), b) a high caffeine dose, and c) the combination of the two stressors. HPBLs from the same subjects exposed to gamma radiation at doses 0.1, 0.3, or 0.5 Gy, displayed more aberrations than those exposed to MT EMFs or the high caffeine dose in a dose-dependent manner. When the cells exposed to these gamma radiation doses were pre-exposed to ...
Source: General Physiology and Biophysics - December 15, 2023 Category: Physiology Authors: Dimitris J Panagopoulos Source Type: research
Mobile telephony radiation exerts genotoxic action and significantly enhances the effects of gamma radiation in human cells
Gen Physiol Biophys. 2023 Dec 8. doi: 10.4149/gpb_2023036. Online ahead of print.ABSTRACTI previously reported induction of chromosomal damage in human peripheral blood lymphocytes (HPBLs) induced by: a) Mobile telephony (MT) electromagnetic fields (EMFs)/electromagnetic radiation (EMR), b) a high caffeine dose, and c) the combination of the two stressors. HPBLs from the same subjects exposed to gamma radiation at doses 0.1, 0.3, or 0.5 Gy, displayed more aberrations than those exposed to MT EMFs or the high caffeine dose in a dose-dependent manner. When the cells exposed to these gamma radiation doses were pre-exposed to ...
Source: General Physiology and Biophysics - December 15, 2023 Category: Physiology Authors: Dimitris J Panagopoulos Source Type: research
Mobile telephony radiation exerts genotoxic action and significantly enhances the effects of gamma radiation in human cells
Gen Physiol Biophys. 2023 Dec 8. doi: 10.4149/gpb_2023036. Online ahead of print.ABSTRACTI previously reported induction of chromosomal damage in human peripheral blood lymphocytes (HPBLs) induced by: a) Mobile telephony (MT) electromagnetic fields (EMFs)/electromagnetic radiation (EMR), b) a high caffeine dose, and c) the combination of the two stressors. HPBLs from the same subjects exposed to gamma radiation at doses 0.1, 0.3, or 0.5 Gy, displayed more aberrations than those exposed to MT EMFs or the high caffeine dose in a dose-dependent manner. When the cells exposed to these gamma radiation doses were pre-exposed to ...
Source: General Physiology and Biophysics - December 15, 2023 Category: Physiology Authors: Dimitris J Panagopoulos Source Type: research
Mobile telephony radiation exerts genotoxic action and significantly enhances the effects of gamma radiation in human cells
Gen Physiol Biophys. 2023 Dec 8. doi: 10.4149/gpb_2023036. Online ahead of print.ABSTRACTI previously reported induction of chromosomal damage in human peripheral blood lymphocytes (HPBLs) induced by: a) Mobile telephony (MT) electromagnetic fields (EMFs)/electromagnetic radiation (EMR), b) a high caffeine dose, and c) the combination of the two stressors. HPBLs from the same subjects exposed to gamma radiation at doses 0.1, 0.3, or 0.5 Gy, displayed more aberrations than those exposed to MT EMFs or the high caffeine dose in a dose-dependent manner. When the cells exposed to these gamma radiation doses were pre-exposed to ...
Source: General Physiology and Biophysics - December 15, 2023 Category: Physiology Authors: Dimitris J Panagopoulos Source Type: research
Five glycosylation-related gene signatures predict the prognostic risks of lung adenocarcinoma
This study aimed to identify glycosylation-related genes associated with lung adenocarcinoma (LUAD) prognosis through comprehensive bioinformatic analysis. Glycosylation-related genes were identified from the Human Gene Nomenclature Committee, and LUAD prognostic genes were screened from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO)-GSE68465 datasets. Glycosylation risk score (GLRS) was calculated to predict LUAD prognostic risk. Samples were grouped into GLRS-high and GLRS-low and compared. The Tumor Immune Dysfunction and Exclusion (TIDE) score was computed to assess the antitumor immune escape possibi...
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Xiao-Hui Liu Yi-Ming Yang Ming-Ming Zhang Hao-Yu Fu Source Type: research
Early-life maternal deprivation in rats increases sensitivity to the subsequent stressors: a pilot study
This study underscores the utility of a two-stage PSS model for more accurately reflecting the complexities inherent in stress-related disorders, including PTSD.PMID:37994426 | DOI:10.4149/gpb_2023022 (Source: General Physiology and Biophysics)
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Maria Komelkova Boris Yushkov Stanislav Fedorov Roman Ibragimov Pavel Platkovskiy Desheng Hu Shanshan Luo Alexey Sarapultsev Source Type: research
Effects of novel mRNA-VEGF@USPIO nanoparticles on human brain microvascular endothelial cell injury
This study shows that mRNA-VEGF@USPIO nanoparticles can repair HBMECs injury.PMID:37994427 | DOI:10.4149/gpb_2023032 (Source: General Physiology and Biophysics)
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Jiang Zhao Zhiyuan Qian Source Type: research
Polydatin inhibited TNF- α-induced apoptosis of skeletal muscle cells through AKT-mediated p38 MAPK and NF-κB pathways
This study investigated the effects and mechanism of polydatin on TNF-α-induced skeletal muscle cells. The skeletal muscle cell atrophy model was established by inducing C2C12 cells with TNF-α. Cell viability, IL-1β levels and cell apoptosis were assessed. The mRNA and protein expression levels of apoptosis-related proteins were measured. Meanwhile, the binding of polydatin to AKT was analyzed by molecular docking. TNF-α reduced cell fusion and viability while up-regulated IL-1β level and promoted cell apoptosis. TNF-α activated AKT, NF-κB, and p38 MAPK signaling pathways. Polydatin reversed these effects induced by...
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Yongli Liu Fang Xie Changhuai Lu Zongbo Zhou Shudong Li Jia Zhong Qian Li Xianfang Shao Source Type: research
Effects of percutaneous coronary intervention via transradial artery access combined with metoprolol on cardiac function and vascular endothelial function in elderly patients with coronary heart disease
Gen Physiol Biophys. 2023 Nov;42(6):531-538. doi: 10.4149/gpb_2023028.ABSTRACTThis research was designed to unveil the impacts of percutaneous coronary intervention via transradial artery access (TRA-PCI) combined with metoprolol on cardiac function and vascular endothelial function in elderly patients with coronary heart disease (CHD). Collectively, 112 CHD patients were enrolled and allocated into a control group (patients treated with TRA-PCI) and an observation group (patients treated with TRA-PCI and metoprolol) following the random number table method (n = 56 patients). The treatment outcome, cardiac function indi...
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Feng Cheng Juan Xu Source Type: research
The effects of the pulsed magnetic field on sepsis-induced liver tissue injury in rats
Gen Physiol Biophys. 2023 Nov;42(6):539-549. doi: 10.4149/gpb_2023026.ABSTRACTSepsis is the host's response to infection and can lead to severe and life-threatening cases. We aimed to investigate the effects of pulsed magnetic field (PMF) on septic liver tissue injury. A total of 28 adult Wistar albino rats were divided equally into four study groups: Sham, PMF-1, PMF-2, and Sepsis, with seven rats in each. Sepsis was performed using the CLP method. PMF-1 and PMF-2 were exposed to 7.5 Hz and 15 Hz PMF, respectively, for 24 hours. After having their livers removed, liver tissues were analysed using histological techniques. ...
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Fikret Gevrek Serkan Yelli Serkan G ürgül Source Type: research
Five glycosylation-related gene signatures predict the prognostic risks of lung adenocarcinoma
This study aimed to identify glycosylation-related genes associated with lung adenocarcinoma (LUAD) prognosis through comprehensive bioinformatic analysis. Glycosylation-related genes were identified from the Human Gene Nomenclature Committee, and LUAD prognostic genes were screened from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO)-GSE68465 datasets. Glycosylation risk score (GLRS) was calculated to predict LUAD prognostic risk. Samples were grouped into GLRS-high and GLRS-low and compared. The Tumor Immune Dysfunction and Exclusion (TIDE) score was computed to assess the antitumor immune escape possibi...
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Xiao-Hui Liu Yi-Ming Yang Ming-Ming Zhang Hao-Yu Fu Source Type: research
Early-life maternal deprivation in rats increases sensitivity to the subsequent stressors: a pilot study
This study underscores the utility of a two-stage PSS model for more accurately reflecting the complexities inherent in stress-related disorders, including PTSD.PMID:37994426 | DOI:10.4149/gpb_2023022 (Source: General Physiology and Biophysics)
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Maria Komelkova Boris Yushkov Stanislav Fedorov Roman Ibragimov Pavel Platkovskiy Desheng Hu Shanshan Luo Alexey Sarapultsev Source Type: research
Effects of novel mRNA-VEGF@USPIO nanoparticles on human brain microvascular endothelial cell injury
This study shows that mRNA-VEGF@USPIO nanoparticles can repair HBMECs injury.PMID:37994427 | DOI:10.4149/gpb_2023032 (Source: General Physiology and Biophysics)
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Jiang Zhao Zhiyuan Qian Source Type: research
Polydatin inhibited TNF- α-induced apoptosis of skeletal muscle cells through AKT-mediated p38 MAPK and NF-κB pathways
This study investigated the effects and mechanism of polydatin on TNF-α-induced skeletal muscle cells. The skeletal muscle cell atrophy model was established by inducing C2C12 cells with TNF-α. Cell viability, IL-1β levels and cell apoptosis were assessed. The mRNA and protein expression levels of apoptosis-related proteins were measured. Meanwhile, the binding of polydatin to AKT was analyzed by molecular docking. TNF-α reduced cell fusion and viability while up-regulated IL-1β level and promoted cell apoptosis. TNF-α activated AKT, NF-κB, and p38 MAPK signaling pathways. Polydatin reversed these effects induced by...
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Yongli Liu Fang Xie Changhuai Lu Zongbo Zhou Shudong Li Jia Zhong Qian Li Xianfang Shao Source Type: research
Effects of percutaneous coronary intervention via transradial artery access combined with metoprolol on cardiac function and vascular endothelial function in elderly patients with coronary heart disease
Gen Physiol Biophys. 2023 Nov;42(6):531-538. doi: 10.4149/gpb_2023028.ABSTRACTThis research was designed to unveil the impacts of percutaneous coronary intervention via transradial artery access (TRA-PCI) combined with metoprolol on cardiac function and vascular endothelial function in elderly patients with coronary heart disease (CHD). Collectively, 112 CHD patients were enrolled and allocated into a control group (patients treated with TRA-PCI) and an observation group (patients treated with TRA-PCI and metoprolol) following the random number table method (n = 56 patients). The treatment outcome, cardiac function indi...
Source: General Physiology and Biophysics - November 23, 2023 Category: Physiology Authors: Feng Cheng Juan Xu Source Type: research
