[Translated article] Influence of augmented renal clearance in the lower incidence of linezolid-related haematological toxicity
CONCLUSION: Our findings suggest a lower incidence and clinical relevance of haematological toxicity in augmented renal clearance patients. Thrombocytopenia was the major event in both populations. This might be related to a lower exposure to the drug due to the higher clearance and likely lower therapeutic efficiency. These results suggest a potential benefit of therapeutic drug monitoring on high risk patients.PMID:37679220 | DOI:10.1016/j.farma.2023.08.003 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - September 7, 2023 Category: Drugs & Pharmacology Authors: Beatriz S ánchez-Sanz Jos é Manuel Caro-Teller Iv án González-Barrios Pedro Pablo Rodr íguez-Quesada Jos é Antonio Hernández-Ramos Jos é Miguel Ferrari-Piquero Source Type: research
Green hospital pharmacy: A sustainable approach to the medication use process in a tertiary hospital
Farm Hosp. 2023 Sep 4:S1130-6343(23)00108-3. doi: 10.1016/j.farma.2023.08.001. Online ahead of print.ABSTRACTBACKGROUND: Sustainable management of healthcare waste has a positive impact on the global environment. In order to reduce it, the sustainable practice of the pharmacotherapeutic process in all its stages is essential.OBJECTIVE: To analyse the sustainability strategies proposed by the pharmacy service to reduce drug waste derived from the pharmacotherapeutic process.SECONDARY OBJECTIVES: To analyse the stage of the pharmacotherapeutic process and the number and type of drugs involved.METHODS: The study was carried o...
Source: Farmacia Hospitalaria - September 6, 2023 Category: Drugs & Pharmacology Authors: Victoria Luc ía Collada Sánchez Elena Villama ñán Bueno Marta Ayll ón Morales Margarita Ruano Encinar Carmen Sobreino Jimenez C Lara Catedra Ester Perez Andreu Alicia Herrero Ambrosio Source Type: research
Lipid profile changes associated with antiretroviral therapies in a real-world cohort
CONCLUSIONS: The lipid profile among elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide fumarate group worsened throughout the follow-up, both in naïve and experienced patients, not so remarkable in the dolutegravir/abacavir/lamivudine group. Both regimens were well tolerated, with similar rates of cardiovascular events.PMID:37673703 | DOI:10.1016/j.farma.2023.07.005 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - September 6, 2023 Category: Drugs & Pharmacology Authors: Sandra Rotea-Salvo V íctor Giménez-Arufe Alejandro Mart ínez-Pradeda Carla Fern ández-Oliveira Álvaro Mena-de-Cea Luis Margusino-Frami ñán Isabel Mart ín-Herranz Purificaci ón Cid-Silva Source Type: research
Green hospital pharmacy: A sustainable approach to the medication use process in a tertiary hospital
Farm Hosp. 2023 Sep 4:S1130-6343(23)00108-3. doi: 10.1016/j.farma.2023.08.001. Online ahead of print.ABSTRACTBACKGROUND: Sustainable management of healthcare waste has a positive impact on the global environment. In order to reduce it, the sustainable practice of the pharmacotherapeutic process in all its stages is essential.OBJECTIVE: To analyse the sustainability strategies proposed by the pharmacy service to reduce drug waste derived from the pharmacotherapeutic process.SECONDARY OBJECTIVES: To analyse the stage of the pharmacotherapeutic process and the number and type of drugs involved.METHODS: The study was carried o...
Source: Farmacia Hospitalaria - September 6, 2023 Category: Drugs & Pharmacology Authors: Victoria Luc ía Collada Sánchez Elena Villama ñán Bueno Marta Ayll ón Morales Margarita Ruano Encinar Carmen Sobreino Jimenez C Lara Catedra Ester Perez Andreu Alicia Herrero Ambrosio Source Type: research
Lipid profile changes associated with antiretroviral therapies in a real-world cohort
CONCLUSIONS: The lipid profile among elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide fumarate group worsened throughout the follow-up, both in naïve and experienced patients, not so remarkable in the dolutegravir/abacavir/lamivudine group. Both regimens were well tolerated, with similar rates of cardiovascular events.PMID:37673703 | DOI:10.1016/j.farma.2023.07.005 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - September 6, 2023 Category: Drugs & Pharmacology Authors: Sandra Rotea-Salvo V íctor Giménez-Arufe Alejandro Mart ínez-Pradeda Carla Fern ández-Oliveira Álvaro Mena-de-Cea Luis Margusino-Frami ñán Isabel Mart ín-Herranz Purificaci ón Cid-Silva Source Type: research
[Translated article] Medication experience and clinical interventions in patients receiving pharmaceutical care: A scoping review of pharmaceutical care practice
CONCLUSIONS: The MedExp is an extensive concept, which encompasses people's life experience who use medications based on their individual, psychological, and social qualities. This MedExp is corporal, intentional, intersubjective, and relational, expanding to the collective because it implies beliefs, culture, ethics, and the socioeconomic and political reality of each person located in their context.PMID:37659906 | DOI:10.1016/j.farma.2023.07.001 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - September 2, 2023 Category: Drugs & Pharmacology Authors: Sof ía Orozco-Solano Martha Milena Silva-Castro Manuel Machuca Source Type: research
[Translated article] Medication experience and clinical interventions in patients receiving pharmaceutical care: A scoping review of pharmaceutical care practice
CONCLUSIONS: The MedExp is an extensive concept, which encompasses people's life experience who use medications based on their individual, psychological, and social qualities. This MedExp is corporal, intentional, intersubjective, and relational, expanding to the collective because it implies beliefs, culture, ethics, and the socioeconomic and political reality of each person located in their context.PMID:37659906 | DOI:10.1016/j.farma.2023.07.001 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - September 2, 2023 Category: Drugs & Pharmacology Authors: Sof ía Orozco-Solano Martha Milena Silva-Castro Manuel Machuca Source Type: research
[Translated article] Medication experience and clinical interventions in patients receiving pharmaceutical care: A scoping review of pharmaceutical care practice
CONCLUSIONS: The MedExp is an extensive concept, which encompasses people's life experience who use medications based on their individual, psychological, and social qualities. This MedExp is corporal, intentional, intersubjective, and relational, expanding to the collective because it implies beliefs, culture, ethics, and the socioeconomic and political reality of each person located in their context.PMID:37659906 | DOI:10.1016/j.farma.2023.07.001 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - September 2, 2023 Category: Drugs & Pharmacology Authors: Sof ía Orozco-Solano Martha Milena Silva-Castro Manuel Machuca Source Type: research
[Translated article] Medication experience and clinical interventions in patients receiving pharmaceutical care: A scoping review of pharmaceutical care practice
CONCLUSIONS: The MedExp is an extensive concept, which encompasses people's life experience who use medications based on their individual, psychological, and social qualities. This MedExp is corporal, intentional, intersubjective, and relational, expanding to the collective because it implies beliefs, culture, ethics, and the socioeconomic and political reality of each person located in their context.PMID:37659906 | DOI:10.1016/j.farma.2023.07.001 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - September 2, 2023 Category: Drugs & Pharmacology Authors: Sof ía Orozco-Solano Martha Milena Silva-Castro Manuel Machuca Source Type: research
[Translated article] Analysis of the appropriateness of antibiotic prophylaxis in surgical procedures in Spain. Protocol for the "ProA-Q" study
DISCUSSION: The results of this clinical study will allow us to focus on specific surgical areas with higher rates of inappropriateness, identify key points of action and guide future strategies for antimicrobial stewardship programs in the area of antibiotic prophylaxis.PMID:37658007 | DOI:10.1016/j.farma.2023.07.003 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - September 1, 2023 Category: Drugs & Pharmacology Authors: Ana Bel én Guisado-Gil Jos é María Gutiérrez-Urbón Almudena Ribed-S ánchez Sonia Luque-Pardos Abraham S ánchez-Cadena Beatriz Mejuto Didiana Jaramillo-Ruiz Germ án Peñalva Jos é Miguel Cisneros Source Type: research
Characterization and real-live results of nebulized voriconazole: A single-center observational study
CONCLUSION: Voriconazole nebulization is well-tolerated and it is not absorbed into the systemic circulation; further research is needed to assess its efficacy.PMID:37612182 | DOI:10.1016/j.farma.2023.07.010 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - August 23, 2023 Category: Drugs & Pharmacology Authors: Maria Larrosa-Garcia S ònia Terradas Campanario Aurora Fern ández Polo Carme Ca ñete Ramírez Alba Pau Parra David Campany Herrero Source Type: research
Oral vancomycin in a pediatric patient with primary sclerosing cholangitis and inflammatory bowel disease
Farm Hosp. 2023 Aug 21:S1130-6343(23)00090-9. doi: 10.1016/j.farma.2023.06.015. Online ahead of print.NO ABSTRACTPMID:37612183 | DOI:10.1016/j.farma.2023.06.015 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - August 23, 2023 Category: Drugs & Pharmacology Authors: Cristo Yared P érez Martin Jos é Ramón Alberto Alonso Jenifer Gonz ález Chávez Mar ía Pilar Díaz Ruiz Marta Su árez González Javier Merino Alonso Source Type: research
Current situation and evolution of the availability of drugs in the paediatric population in Spain
CONCLUSIONS: Drugs with authorised indications are increasingly available in the paediatric population and the trend is to extend the indication of authorised drugs to the adult population. However, barriers in terms of financing and marketing need to be expedited and overcome to facilitate access to them.PMID:37612184 | DOI:10.1016/j.farma.2023.07.014 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - August 23, 2023 Category: Drugs & Pharmacology Authors: Juan Diego Paradas-Palomo Luc ía Yunquera-Romero Carmen Gallego-Fern ández Source Type: research
Adjusted indirect comparison of zanubrutinib and ibrutinib in first-line treatment of chronic lymphocytic leukemia
CONCLUSIONS: Assuming the uncertainty associated with the adjusted indirect comparison, zanubrutinib could be considered equivalent in efficacy to ibrutinib, however, the presence of differentiating safety features precludes assigning the two alternatives as equivalent therapeutic alternatives.PMID:37612185 | DOI:10.1016/j.farma.2023.07.006 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - August 23, 2023 Category: Drugs & Pharmacology Authors: Francisco Javier Salmer ón-Navas Ester Mar ía Barreiro-Fernández Silvia F énix-Caballero Source Type: research
Pharmacokinetics of eculizumab in adult and pediatric patients with atypical hemolytic uremic syndrome and C3 glomerulopathy
CONCLUSIONS: The present study reports supratherapeutic concentrations of eculizumab in patients with aHUS, and defines higher concentrations than those described in the data sheet to achieve blockade, thus encouraging the personalization of treatment with eculizumab.PMID:37612186 | DOI:10.1016/j.farma.2023.07.009 (Source: Farmacia Hospitalaria)
Source: Farmacia Hospitalaria - August 23, 2023 Category: Drugs & Pharmacology Authors: Alba Pau Parra Natalia Ramos Janire Perurena-Prieto Silvia Manrique-Rodr íguez Monica Climente Laura Garc ía Quintanilla Ángel Escolano Marta Miarons en nombre del grupo PK-ECU-ORPHAR Source Type: research
