European Journal of Gynaecological Oncology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Multidisciplinary management of advanced ovarian cancer for an optimal therapeutic strategy.
Authors: Heudel PE, Devouassoux-Shisheboran M, Taieb S, Genestie C, Selle F, Morice P, Rouzier R, Ray-Coquard I
Abstract
The management of advanced ovarian cancer generally requires specialist multidisciplinary teamwork to achieve optimum outcomes. Preoperative computed tomography scans are the imaging modality of choice in determining the extent of disease and aiding in surgical planning. Histological classification is crucial to define various subtypes with their different behaviour and prognosis and to plan the best therapeutic strategy. Pathological prognostic factors, such as histological type, degree...
Source: European Journal of Gynaecological Oncology - July 1, 2018 Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
Role of cancer stem cells and microRNA in resistance to chemotherapy in patients with ovarian cancer.
Authors: Markowska A, Sajdak S
Abstract
Despite the introduction of "the golden standard" in chemotherapy for ovarian cancer (taxanes/platinum), a relapse of the disease is noted in 80% of women treated in this manner. Studies on ovarian cancer stem cells (CSCs) and attempts at treatment using salinomycin, isolated from Streptonzyces albus and endotoxin of Clostridium peifringens, are promising, in particular because CSC markers have been identified. Resistence of ovarian cancer cells to paclitaxel and cisplatin is associated with a reduced expression of miR-30c, miR-130, and miR335, which results in activ...
Source: European Journal of Gynaecological Oncology - July 1, 2018 Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
Automated breast volume scanner (ABVS) in breast cancer - a review.
Authors: Xiao Y, Wang Z, Chen Z
Abstract
The early detection of breast cancer is essential for its timely diagnosis and treatment. Many imaging modalities are continually being developed to screen and diagnose breast cancer at an early stage. Especially, ultrasound (US) is one of useful diagnostic tools to dis- tinguish benign from malignant masses of the breast. However, the US image has some limitations, such as low resolution and low con- trast, speckle noise, and blurry edges between various organs. Recent technological advancements in the area resulted in development of automated breast volume scanner...
Source: European Journal of Gynaecological Oncology - July 1, 2018 Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
Correlation between the body mass index of patients with breast cancer before and after chemotherapy.
The objective of this work was to show how the influence of the microenvironment in tumor cells and consequently the onset and tumor progression is becoming increasingly more evident. Cancer is the second leading cause of death in the developed world, surpassed only by heart disease and obesity, and is increasingly recognised as an oncogenic factor in the genesis of this tumor. Inflammatory me- diators related to obesity are suspected to play a role in oncogenic modification of substrates metabolism of nutrients, most patients diagnosed with breast cancer underwent chemotherapy treatment, and this may be an aggravating fac...
Source: European Journal of Gynaecological Oncology - July 1, 2018 Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
Expression of IncRNA UCA1 in ovarian cancer and its clinical significance.
CONCLUSION: IncRNA-UCA1 may play a vital role in the metastasis of ovarian cancer and it is expected to be a potential novel biomarker and therapeutic target of ovarian cancer.
PMID: 29953778 [PubMed - in process] (Source: European Journal of Gynaecological Oncology)
Source: European Journal of Gynaecological Oncology - July 1, 2018 Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
Complications following type 3 excision by needle excision of the transformation zone: a case series report.
CONCLUSION: NETZ is associated with a number of complications and recognition of risk factors should be considered when planning type 3 excisional procedures and counseling women.
PMID: 29953779 [PubMed - in process] (Source: European Journal of Gynaecological Oncology)
Source: European Journal of Gynaecological Oncology - July 1, 2018 Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
Defective expression of polarity protein Par3 promotes cervical tumorigenesis and metastasis.
CONCLUSIONS: The reduced Par3 expression in cervical cancer indicates tumor-suppressive properties of Par3 that may be a marker of poor prognosis in cervical cancer patients, and the molecular determinants of epithelial polarity which have tumorigenesis enhancing impact, might through EMT.
PMID: 29953780 [PubMed - in process] (Source: European Journal of Gynaecological Oncology)
Source: European Journal of Gynaecological Oncology - July 1, 2018 Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research
