Yiqi Jiedu Xiaoying Decoction Improves Experimental Autoimmune Thyroiditis in Rats by Regulating Th17/Treg Cell Balance
CONCLUSION: YJXD exerted therapeutic effects on EAT by regulating the Th17/Treg cell balance, modulating the production of Th17- and Treg-related cytokines and the expression of transcriptional factors.PMID:38317460 | DOI:10.2174/0118715303256311231122094516 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 6, 2024 Category: Drugs & Pharmacology Authors: Hui Zhu Shumin Mu Shiyin Liu Yang Cui Jianyu Ren Enquan Yang Lining Wang Xiaoke Cui Ailing Ren Source Type: research

Highlights from the Top 100 Most Influential Articles Regarding the Nuclear Receptor PPAR- γ: A Bibliometric Analysis
CONCLUSION: The present study identified the top 100 most influential articles in the field of PPAR-γ, which help global researchers to better understand research perspectives and develop future research directions of PPAR-γ.PMID:38317461 | DOI:10.2174/0118715303265935231114073638 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 6, 2024 Category: Drugs & Pharmacology Authors: Si Wu Haijiao Dai Xianxiang Bai Zhen Wu Xianglei Wang Bin Xiao Source Type: research

Comorbidity, Eating Behaviors and Smartphone Addiction in Italian Nurses' Characteristics
CONCLUSION: Female nurses, overweight and obese nurses with low physical activity practice, seemed to spend more time with their smartphones. Healthcare organizations should consider findings to prevent unhealthy lifestyles among nurses, which could negatively influence the whole healthcare system.PMID:38317462 | DOI:10.2174/0118715303271067231129103920 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 6, 2024 Category: Drugs & Pharmacology Authors: Elsa Vitale Rocco Mea Source Type: research

Study of MicroRNA-124 in Patients with Lupus Nephritis
Conclusion: In the present study, a comparison of MicroRNA-124 in LN patients with different stages compared to normal control showed a statistically significant decrease in Micro-RNA124 in patients with lupus nephritis p <0.001 with significant correlation to the patients' different clinical and serological findings of SLE. Therefore, it may be used as a new noninvasive therapeutic approach to monitor response to therapy, predict relapses, and identify the degree of the activity of the disease or the progression to the chronic stage.PMID:38317459 | DOI:10.2174/0118715303250919231010073608 (Source: Endocrine, Metabolic ...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 6, 2024 Category: Endocrinology Authors: Mostafa Abdelsalam Maysaa El Sayed Zaki Nermin Youssef Abo El-Kheir Mona Foda Salama Asmaa Osama Bakr Seddik Osman Source Type: research

Yiqi Jiedu Xiaoying Decoction Improves Experimental Autoimmune Thyroiditis in Rats by Regulating Th17/Treg Cell Balance
CONCLUSION: YJXD exerted therapeutic effects on EAT by regulating the Th17/Treg cell balance, modulating the production of Th17- and Treg-related cytokines and the expression of transcriptional factors.PMID:38317460 | DOI:10.2174/0118715303256311231122094516 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 6, 2024 Category: Endocrinology Authors: Hui Zhu Shumin Mu Shiyin Liu Yang Cui Jianyu Ren Enquan Yang Lining Wang Xiaoke Cui Ailing Ren Source Type: research

Highlights from the Top 100 Most Influential Articles Regarding the Nuclear Receptor PPAR- γ: A Bibliometric Analysis
CONCLUSION: The present study identified the top 100 most influential articles in the field of PPAR-γ, which help global researchers to better understand research perspectives and develop future research directions of PPAR-γ.PMID:38317461 | DOI:10.2174/0118715303265935231114073638 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 6, 2024 Category: Endocrinology Authors: Si Wu Haijiao Dai Xianxiang Bai Zhen Wu Xianglei Wang Bin Xiao Source Type: research

Comorbidity, Eating Behaviors and Smartphone Addiction in Italian Nurses' Characteristics
CONCLUSION: Female nurses, overweight and obese nurses with low physical activity practice, seemed to spend more time with their smartphones. Healthcare organizations should consider findings to prevent unhealthy lifestyles among nurses, which could negatively influence the whole healthcare system.PMID:38317462 | DOI:10.2174/0118715303271067231129103920 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 6, 2024 Category: Endocrinology Authors: Elsa Vitale Rocco Mea Source Type: research

A Case of Intractable Hypophosphatemia in a Patient with Guillain-Barr é Syndrome and Encephalitis after SARS-CoV-2 Infection
CONCLUSION: Early diagnosis is important for the management of Guillain-Barré syndrome associated with SARS-CoV-2 infection. Moreover, in order to prevent life-threatening long-term persistent electrolyte disturbances in non-seriously ill patients, clinicians should pay particular attention to their electrolyte status.PMID:38314683 | DOI:10.2174/0118715303261924231117055702 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 5, 2024 Category: Drugs & Pharmacology Authors: Yawen Zheng Yuanyuan Hou Mingzhu Qi Yongxiang Zhang Chao Han Hui Sun Jiang Li Source Type: research

A Case of Intractable Hypophosphatemia in a Patient with Guillain-Barr é Syndrome and Encephalitis after SARS-CoV-2 Infection
CONCLUSION: Early diagnosis is important for the management of Guillain-Barré syndrome associated with SARS-CoV-2 infection. Moreover, in order to prevent life-threatening long-term persistent electrolyte disturbances in non-seriously ill patients, clinicians should pay particular attention to their electrolyte status.PMID:38314683 | DOI:10.2174/0118715303261924231117055702 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 5, 2024 Category: Endocrinology Authors: Yawen Zheng Yuanyuan Hou Mingzhu Qi Yongxiang Zhang Chao Han Hui Sun Jiang Li Source Type: research

Organelle Targeted Drug Delivery: Key Challenges, Recent Advancements and Therapeutic Implications
Endocr Metab Immune Disord Drug Targets. 2024 Jan 31. doi: 10.2174/0118715303282573240112104035. Online ahead of print.ABSTRACTOrganelle-specific targeted drug delivery has emerged as a promising approach in the field of drug delivery and therapeutics. This innovative strategy involves the precise delivery of therapeutic agents to specific organelles within cells, such as the nucleus, mitochondria, endoplasmic reticulum, or lysosomes, with the aim of enhancing drug efficacy while minimizing offtarget effects. Despite its tremendous potential, organelle-specific drug delivery faces several key challenges. One major challeng...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 2, 2024 Category: Drugs & Pharmacology Authors: Dilpreet Singh Source Type: research

A Review on the Role of Inflammation in Coronavirus Disease
Endocr Metab Immune Disord Drug Targets. 2024 Feb 1. doi: 10.2174/0118715303265274231204075802. Online ahead of print.ABSTRACTThe respiratory illness known as COVID-19 is caused by the novel coronavirus, SARS-CoV-2. While the precise pathogenic mechanism of COVID-19 remains unclear, the occurrence of a cytokine storm subsequent to viral infection plays a pivotal role in the initiation and advancement of the disease. The infection of SARS-CoV-2 induces a state of immune system hyperactivity, leading to an excessive production of inflammatory cytokines. Consequently, the identification of the various signaling pathways impli...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 2, 2024 Category: Drugs & Pharmacology Authors: Arezoo Lotfi Pouran Hajian Laleh Abbasi Morad Kohandel Gargari Najmeh Nameh Goshay Fard Delaram Naderi Source Type: research

Organelle Targeted Drug Delivery: Key Challenges, Recent Advancements and Therapeutic Implications
Endocr Metab Immune Disord Drug Targets. 2024 Jan 31. doi: 10.2174/0118715303282573240112104035. Online ahead of print.ABSTRACTOrganelle-specific targeted drug delivery has emerged as a promising approach in the field of drug delivery and therapeutics. This innovative strategy involves the precise delivery of therapeutic agents to specific organelles within cells, such as the nucleus, mitochondria, endoplasmic reticulum, or lysosomes, with the aim of enhancing drug efficacy while minimizing offtarget effects. Despite its tremendous potential, organelle-specific drug delivery faces several key challenges. One major challeng...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 2, 2024 Category: Endocrinology Authors: Dilpreet Singh Source Type: research

A Review on the Role of Inflammation in Coronavirus Disease
Endocr Metab Immune Disord Drug Targets. 2024 Feb 1. doi: 10.2174/0118715303265274231204075802. Online ahead of print.ABSTRACTThe respiratory illness known as COVID-19 is caused by the novel coronavirus, SARS-CoV-2. While the precise pathogenic mechanism of COVID-19 remains unclear, the occurrence of a cytokine storm subsequent to viral infection plays a pivotal role in the initiation and advancement of the disease. The infection of SARS-CoV-2 induces a state of immune system hyperactivity, leading to an excessive production of inflammatory cytokines. Consequently, the identification of the various signaling pathways impli...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 2, 2024 Category: Endocrinology Authors: Arezoo Lotfi Pouran Hajian Laleh Abbasi Morad Kohandel Gargari Najmeh Nameh Goshay Fard Delaram Naderi Source Type: research

Mapping the Landscape of Obesity Effects on Male Reproductive Function: A Bibliometric Study
CONCLUSION: The impact of obesity on male reproductive disorders has been extensively studied. Currently, research in this field primarily focuses on male sperm function, sperm quality, and the effects or mechanisms of cells on male reproduction. Future trends in this field should concentrate on the relationship between male fertility and energy metabolism, as well as the endocrine function of adipose tissue. This study comprehensively analyzes the current research status and global trends in obesity and male reproductive disorders. We also discuss the future developments in this field, making it easier for researchers to ...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 1, 2024 Category: Drugs & Pharmacology Authors: Yanhong Wei Meihua Liao Yiming Lu Xiaocan Lei Junli Wang Linlin Hu Xiaoqiong Luo Source Type: research

Evaluation of Blood Lactate among Different Player Roles: A Pilot Study on Competitive Young Male Soccer Players
CONCLUSION: These results suggest that aerobic mechanisms can also use LA as an energy source, contributing to the reduction of its blood concentration. This effect can be due to reduced maximal work during a soccer match and to the LA removal during exercise at reduced intensity. These data can provide indications for planning suitable training strategies for young male soccer players.PMID:38299283 | DOI:10.2174/0118715303269744231221101401 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - February 1, 2024 Category: Drugs & Pharmacology Authors: Rosaria Arcone Pietro Montesano Maurizio Di Silvestro Antonio D'Errico Rosaria Meccariello Filomena Mazzeo Source Type: research