Comparison of the antifungal effect of voriconazole and fluconazole on oral candidiasis before and during radiotherapy
Conclusion: The current study results showed that voriconazole was not more effective thanfluconazole in the treatment of oral candidiasis in patients undergoing head ‑and‑neck radiotherapy.Key Words: Antifungal agents, candidiasis oral, fluconazole, head ‑and‑neck neoplasms,radiotherapy, voriconazole (Source: Dental Research Journal)
Source: Dental Research Journal - November 9, 2022 Category: Dentistry Source Type: research
Evaluation of the efficacy of Echinacea on clinical indices of Erosive Oral Lichen Planus: A randomized double ‑blind clinical trial
Conclusion: We showed that Echinacea is an effective and complementary therapy for OLP.Furthermore, in short ‑term usage, Echinacea is almost completely tolerable.Key Words: Echinacea purpurea, lichen planus, visual analog scale pain, wound healing (Source: Dental Research Journal)
Source: Dental Research Journal - November 9, 2022 Category: Dentistry Source Type: research
Comparison of subcutaneous inflammatory response induced by elastomeric orthodontic ligatures coated with silver and zinc oxide nanoparticles with control group on rats
Conclusion: There was a significant more inflammation in the groups receiving ZnO and silvernanoparticles compared to the control group in 15 ‑ and 30‑day samples. Silver nanoparticles areprobably safer than zinc nanoparticles for tissue and a better material to choose for antibacterial effects.Key Words: Elastomeric ligatures, silver nanoparticles, subcutaneous inflammation, zinc oxidenanoparticles (Source: Dental Research Journal)
Source: Dental Research Journal - November 9, 2022 Category: Dentistry Source Type: research
Changes in nasal symmetry after presurgical nasoalveolar molding in infants treated with complete unilateral cleft lip and palate: A follow ‑up study
Conclusion: The improvement in the nasal symmetry after cheiloplasty in PNAM ‑treated patientsis maintained till 1 year postsurgically though there is a nonsignificant relapse.Key Words: Cleft lip, cleft palate, follow ‑up studies, nasoalveolar molding (Source: Dental Research Journal)
Source: Dental Research Journal - November 9, 2022 Category: Dentistry Source Type: research
Prosthetic rehabilitation of untailored defects using patient ‑specific implants
The restoration of speech, deglutition, mastication, and respiration in patients with bimaxillary resection involving the maxillae, hard and soft palates, and paranasal sinuses poses a significant challenge. This clinical report describes the prosthodontic management of a patient with bilateral maxillectomy caused due to post ‑COVID‑19 mucormycosis. A patient-specific implants (PSI) that matched the remnants of the zygoma complex was designed to improve the patient’s severely impaired speech and swallowing. The patient’s postsurgical anatomy was first visualized using three‑dimensional computed tomography data. F...
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
Investigation of the effect of bonding factors on strength of porcelain bond to soft metal alloys after application of thermal cycle
This study aimed to investigate the effect of metal conditioner on controlling the oxide layer formed on the surface of the Sintron alloy and the strength of the metal–porcelain bond. Materials and Methods: In this in vitro study, 33 samples were divided into three groups based on surface treatment (n = 11). In all three groups, an oxide layer was created. In the first group, Shofu metal conditioner, in the second group, metal conditioner of Creation, and in the third group, no metal conditioner was a pplied. All samples were then subjected to 3000 heat cycles between 5° and 55°C with a stop time of 5 s. The specimens ...
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
Effect of sintering temperature on translucency parameter of zirconia blocks
This study aimed to assess the effect of sintering temperature on the translucency of Ivoclar e. max ZirCAD (IEZ), and White Peaks Symphony (WPS) zirconia blocks. Materials and Methods: In this in vitro experimental study, 30 IEZ and 30 WPS zirconia blocks measuring 10 mm × 10 mm × 1 mm were prepared and underwent sintering in three subgroups at 1440°C, 1500°C, and 1530°C. The specimens were then photographed against a black and a white background with a standard digital camera. The L*, a*, and b* color parameters were measured using Adobe Photoshop software, an d translucency was calculated. Data were analyzed using ...
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
A comparative evaluation of fracture toughness, flexural strength, and acid buffer capability of a bulk ‑fill alkasite with high‑strength glass‑ionomer cement: An in vitro study
Background: Although glass ‑ionomer cement (GIC) has many unique properties and advantages, it still lacks favorable mechanical properties. Cention N is a recent alkasite material with excellent mechanical properties. The purpose of this study was to compare the mechanical properties (fracture toughness [FT] and flexural st rength [FS]) and acid buffer capability of an alkasite material to GIC. Materials and Methods: In this in vitro study, a total of 60 samples were prepared using Cention N or GIC. Twenty specimens (n = 10) were prepared using beam‑shaped Teflon molds for FS, and twenty specimens (n = 10) were prepa r...
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
Opportunities and threats of e ‑learning in dental education in viewpoints of faculty members: A Mixed method study
Conclusion: The majority o f the faculty members agreed with the use of e‑learning in dental education and considered it as an opportunity. However, educational design for blended learning, creation of appropriate infrastructures, and empowerment of human resources as e‑teacher and e‑student were emphasized as key requi rements for e‑learning development in dental schools. Key Words: Coronavirus disease‑19, dental education, dentistry, e‑learning, experience, mixed‑method, perceptions, qualitative (Source: Dental Research Journal)
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
Comparison of clinical and radiological outcomes using crestal approach sinus kit and piezoelectric surgery for sinus membrane elevation: A prospective clinical trial
Background: To overcome the drawbacks of sinus floor augmentation procedures newer surgical techniques to reduce sinus perforation such as crestal approach sinus kit (CAS) and piezosurgery, which are minimally invasive procedures enabling uncomplicated sinus elevation have evolved. The aim of the present study was to investigate the performance of CAS kit compared to piezosurgery during maxillary sinus membrane elevation. Materials and Methods: A total of 40 subjects requiring maxillary sinus membrane augmentation for rehabilitation with implant prosthesis in posterior maxilla were included in the study. The current study ...
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
Effect of microsurgical technique for root coverage using modified coronally advanced flap with connective tissue graft- Randomized controlled clinical trial
Background: The aim of the study was to compare the root coverage percentage and other clinical outcomes in Millers Class I and Class II gingival recessions (GR) treated with modified coronally advanced flap (MCAF) combined with connective tissue graft (CTG) using macro and microsurgical approaches. Materials and Methods: In this controlled clinical trial, a total of 32 Miller ’s Class I and Class II GR defects were randomly assigned to the control and test groups (16 in each group). All the patients were treated with MCAF with CTG as the root coverage procedure. For the control and test groups, the procedure was perform...
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
Evaluation of CD4+ tumor ‑infiltrating lymphocyte association with some clinicopathological indices of oral squamous cell carcinoma
Background: The delayed diagnosis of oral squamous cell carcinoma (OSCC) affects therapeutic and prognostic strategies, and provides regional recurrence or distant metastasis. The tumor ‑infiltrating lymphocytes (TILs) are known as a critical diagnostic biomarker in antitumor immune response. We evaluated the association between CD4+ T‑lymphocyte marker, some clinicopathological indices, and the impact of TILs on the stage and grade of OSCC. Materials and Methods: In this cross ‑sectional study, 37 OSCC specimens including 16 early and 21 advanced stages (categorized base‑on recent clinical oncology references) and...
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
In vivo comparison of bioceramic putty and mineral trioxide aggregate as pulpotomy medicament in primary molars. A 12 ‑month follow‑up randomized clinical trial
Conclusion: Bioceramic putty exhibited comparable results to MTA. Hence, it can be considered alternative pulpotomy agent. Key Words: Bioceramic, mineral trioxide aggregate, pulpotomy (Source: Dental Research Journal)
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
Association of interleukin ‑17A gene promoter polymorphism with the susceptibility to generalized chronic periodontitis in an Iranian population
Background: Chronic periodontitis (CP) is characterized by an immune response, leading to the destruction of periodontal supporting tissue. The effect of inflammatory and genetic factors on periodontitis has been evaluated previously. The interleukin (IL ‑17) as an inflammation regulator seems to play a critical role in periodontitis pathogenesis. Here, in the current study, we aimed to investigate the association of ‑197 G> A (rs2275913) IL ‑17 gene promoter polymorphism with generalized severe CP in an Iranian population. Materials and Methods: In this case–control study, a total of 54 patients with periodontitis...
Source: Dental Research Journal - October 9, 2022 Category: Dentistry Source Type: research
Design –computer‑aided manufacturing guided implant‑supported prosthesis in a fibular graft reconstructed mandible: A 7‑year follow‑up of a case
Reconstruction of functional occlusion in case of a large surgical defect of the mandibleinvolving partial mandibulectomy remains a significant challenge to the maxillofacial surgeon andprosthodontist. Removable appliances and the conventional implant ‑supported prosthesis areprecluded in this case due to the absence of normal anatomical contours of the bone. In recentyears, due to the advancement of technology, bone graft reconstruction with computer ‑guidedrehabilitation of the functional occlusion has been advocated to reverse the debilitating effectsof the hemimandibulectomy defect. This clinical report describes t...
Source: Dental Research Journal - September 14, 2022 Category: Dentistry Source Type: research
