Effect of adenosine triphosphate on amiodarone-induced optic neuropathy in rats: Biochemical and Histopathological Evaluation
CONCLUSION: The biochemical and histopathological results of this study demonstrated that amiodarone at high doses caused more severe optic neuropathy inducing oxidative damage, but ATP could relatively antagonize these negative effects on the optic nerve. Therefore, we believe that ATP may be beneficial in preventing amiodarone-induced optic neuropathy.PMID:37335833 | DOI:10.1080/15569527.2023.2227265 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - June 19, 2023 Category: Toxicology Authors: Kemal Bayrak çeken Rukiye Kilic Ucgul Taha Coban Gulce Yaz ıcı Halis Suleyman Source Type: research

Cytological and Functional Effect of Complement 3a on Human Scleral Fibroblasts
CONCLUSIONS: These results indicated that C3a-induced complement activation is potentially involved in inducing myopic-associated scleral extracellular matrix remodeling via mediating the proliferation and function of HSFs.PMID:37335830 | DOI:10.1080/15569527.2023.2226711 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - June 19, 2023 Category: Toxicology Authors: Kang Xiao Ying Jie Mingyue Luo Qin Long Source Type: research

Effect of adenosine triphosphate on amiodarone-induced optic neuropathy in rats: Biochemical and Histopathological Evaluation
CONCLUSION: The biochemical and histopathological results of this study demonstrated that amiodarone at high doses caused more severe optic neuropathy inducing oxidative damage, but ATP could relatively antagonize these negative effects on the optic nerve. Therefore, we believe that ATP may be beneficial in preventing amiodarone-induced optic neuropathy.PMID:37335833 | DOI:10.1080/15569527.2023.2227265 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - June 19, 2023 Category: Toxicology Authors: Kemal Bayrak çeken Rukiye Kilic Ucgul Taha Coban Gulce Yaz ıcı Halis Suleyman Source Type: research

Determination of heavy metals and risk assessment in nail cosmetics sold in Seoul, Korea
The objective of this study was to evaluate some toxic levels of nail cosmetics marketed in Seoul, Korea and health risk assessment on human.METHODS: We collected 45 random nail cosmetics and analyzed for lead, cadmium, arsenic and antimony by inductively coupled plasma-optical emission spectrometry (ICP-OES).RESULTS: Four metals concentrations were Pb 0.037 ± 0.083 (<LOD ∼ 0.322) mg/kg, Cd 0.021 ± 0.058 (<LOD ∼0.342) mg/kg, As 0.094 ± 0.278 (<LOD ∼ 1.696) mg/kg and Sb 6.75 ± 17.54 (<LOD∼59.017) mg/kg respectively. The concentrations of antimony were significantly higher than other metal concentrati...
Source: Cutaneous and Ocular Toxicology - June 14, 2023 Category: Toxicology Authors: Suun Kim Chaeman Choi Myeongsook Lee Insook Hwang Source Type: research

Toxicological Evaluation of a Nonlethal Riot Control Combinational Formulation upon Dermal Application Using Animal Models
Cutan Ocul Toxicol. 2023 Jun 14:1-43. doi: 10.1080/15569527.2023.2220393. Online ahead of print.ABSTRACTNumerous adverse effects on human health have been reported in epidemiological studies of oleoresin capsicum (OC) and other riot control agents (RCAs). Importantly, the daunting risk of such RCAs can be neutralized by optimizing the desired concentration of such agents for mob dispersal. Hence, a nonlethal riot control combinational formulation (NCF) was prepared for dispersing rioters without imparting fatal outcomes. However, for desired utilization of NCF, it is essential to recognize its extent of potential toxicity....
Source: Cutaneous and Ocular Toxicology - June 14, 2023 Category: Toxicology Authors: Sanghita Das Achintya Saha Amartya Banerjee Danswrang Goyary Sanjeev Karmakar Sanjai Kumar Dwivedi Pronobesh Chattopadhyay Source Type: research

Determination of heavy metals and risk assessment in nail cosmetics sold in Seoul, Korea
The objective of this study was to evaluate some toxic levels of nail cosmetics marketed in Seoul, Korea and health risk assessment on human.METHODS: We collected 45 random nail cosmetics and analyzed for lead, cadmium, arsenic and antimony by inductively coupled plasma-optical emission spectrometry (ICP-OES).RESULTS: Four metals concentrations were Pb 0.037 ± 0.083 (<LOD ∼ 0.322) mg/kg, Cd 0.021 ± 0.058 (<LOD ∼0.342) mg/kg, As 0.094 ± 0.278 (<LOD ∼ 1.696) mg/kg and Sb 6.75 ± 17.54 (<LOD∼59.017) mg/kg respectively. The concentrations of antimony were significantly higher than other metal concentrati...
Source: Cutaneous and Ocular Toxicology - June 14, 2023 Category: Toxicology Authors: Suun Kim Chaeman Choi Myeongsook Lee Insook Hwang Source Type: research

Toxicological Evaluation of a Nonlethal Riot Control Combinational Formulation upon Dermal Application Using Animal Models
Cutan Ocul Toxicol. 2023 Jun 14:1-43. doi: 10.1080/15569527.2023.2220393. Online ahead of print.ABSTRACTNumerous adverse effects on human health have been reported in epidemiological studies of oleoresin capsicum (OC) and other riot control agents (RCAs). Importantly, the daunting risk of such RCAs can be neutralized by optimizing the desired concentration of such agents for mob dispersal. Hence, a nonlethal riot control combinational formulation (NCF) was prepared for dispersing rioters without imparting fatal outcomes. However, for desired utilization of NCF, it is essential to recognize its extent of potential toxicity....
Source: Cutaneous and Ocular Toxicology - June 14, 2023 Category: Toxicology Authors: Sanghita Das Achintya Saha Amartya Banerjee Danswrang Goyary Sanjeev Karmakar Sanjai Kumar Dwivedi Pronobesh Chattopadhyay Source Type: research

Determination of heavy metals and risk assessment in nail cosmetics sold in Seoul, Korea
The objective of this study was to evaluate some toxic levels of nail cosmetics marketed in Seoul, Korea and health risk assessment on human.METHODS: We collected 45 random nail cosmetics and analyzed for lead, cadmium, arsenic and antimony by inductively coupled plasma-optical emission spectrometry (ICP-OES).RESULTS: Four metals concentrations were Pb 0.037 ± 0.083 (<LOD ∼ 0.322) mg/kg, Cd 0.021 ± 0.058 (<LOD ∼0.342) mg/kg, As 0.094 ± 0.278 (<LOD ∼ 1.696) mg/kg and Sb 6.75 ± 17.54 (<LOD∼59.017) mg/kg respectively. The concentrations of antimony were significantly higher than other metal concentrati...
Source: Cutaneous and Ocular Toxicology - June 14, 2023 Category: Toxicology Authors: Suun Kim Chaeman Choi Myeongsook Lee Insook Hwang Source Type: research

Toxicological Evaluation of a Nonlethal Riot Control Combinational Formulation upon Dermal Application Using Animal Models
Cutan Ocul Toxicol. 2023 Jun 14:1-43. doi: 10.1080/15569527.2023.2220393. Online ahead of print.ABSTRACTNumerous adverse effects on human health have been reported in epidemiological studies of oleoresin capsicum (OC) and other riot control agents (RCAs). Importantly, the daunting risk of such RCAs can be neutralized by optimizing the desired concentration of such agents for mob dispersal. Hence, a nonlethal riot control combinational formulation (NCF) was prepared for dispersing rioters without imparting fatal outcomes. However, for desired utilization of NCF, it is essential to recognize its extent of potential toxicity....
Source: Cutaneous and Ocular Toxicology - June 14, 2023 Category: Toxicology Authors: Sanghita Das Achintya Saha Amartya Banerjee Danswrang Goyary Sanjeev Karmakar Sanjai Kumar Dwivedi Pronobesh Chattopadhyay Source Type: research

Determination of heavy metals and risk assessment in nail cosmetics sold in Seoul, Korea
The objective of this study was to evaluate some toxic levels of nail cosmetics marketed in Seoul, Korea and health risk assessment on human.METHODS: We collected 45 random nail cosmetics and analyzed for lead, cadmium, arsenic and antimony by inductively coupled plasma-optical emission spectrometry (ICP-OES).RESULTS: Four metals concentrations were Pb 0.037 ± 0.083 (<LOD ∼ 0.322) mg/kg, Cd 0.021 ± 0.058 (<LOD ∼0.342) mg/kg, As 0.094 ± 0.278 (<LOD ∼ 1.696) mg/kg and Sb 6.75 ± 17.54 (<LOD∼59.017) mg/kg respectively. The concentrations of antimony were significantly higher than other metal concentrati...
Source: Cutaneous and Ocular Toxicology - June 14, 2023 Category: Toxicology Authors: Suun Kim Chaeman Choi Myeongsook Lee Insook Hwang Source Type: research

Toxicological Evaluation of a Nonlethal Riot Control Combinational Formulation upon Dermal Application Using Animal Models
Cutan Ocul Toxicol. 2023 Jun 14:1-43. doi: 10.1080/15569527.2023.2220393. Online ahead of print.ABSTRACTNumerous adverse effects on human health have been reported in epidemiological studies of oleoresin capsicum (OC) and other riot control agents (RCAs). Importantly, the daunting risk of such RCAs can be neutralized by optimizing the desired concentration of such agents for mob dispersal. Hence, a nonlethal riot control combinational formulation (NCF) was prepared for dispersing rioters without imparting fatal outcomes. However, for desired utilization of NCF, it is essential to recognize its extent of potential toxicity....
Source: Cutaneous and Ocular Toxicology - June 14, 2023 Category: Toxicology Authors: Sanghita Das Achintya Saha Amartya Banerjee Danswrang Goyary Sanjeev Karmakar Sanjai Kumar Dwivedi Pronobesh Chattopadhyay Source Type: research

Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research

Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research

Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research

Tamoxifen related chorioretinal structural changes
CONCLUSIONS: Increased choroidal thickness may be the initial finding of subclinical tamoxifen-induced retinopathy. Patients with breast cancer undergoing tamoxifen therapy may be screened prior to tamoxifen therapy and followed during treatment by SD-OCT.PMID:37272809 | DOI:10.1080/15569527.2023.2220388 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - June 5, 2023 Category: Toxicology Authors: İnci Elif Erbahçeci Timur Vehbi A çıkgöz Nagihan U ğurlu B ülent Yalçın Mehmet Ali Nahit Şendur Mutlu H ızal Halil Kara Source Type: research