Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
CONCLUSION: Our results demonstrate that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
CONCLUSION: Our results demonstrate that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
CONCLUSION: Our results demonstrate that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
Conclusion: Our results demonstrates that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
Conclusion: Our results demonstrates that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
Conclusion: Our results demonstrates that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
Conclusion: Our results demonstrates that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
Conclusion: Our results demonstrates that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
Conclusion: Our results demonstrates that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
Conclusion: Our results demonstrates that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Potential inhibition of 12- < em > O < /em > -tetradecanoylphorbol-13-acetate-induced inflammation, hyperproliferation, and hyperplasiogenic responses by celecoxib in mouse skin
Conclusion: Our results demonstrates that topical celecoxib can reduce the inflammation, hyperproliferation, and hyperplasiogenic events of skin insults suggesting that it may prove to be a valuable management option for cutaneous lesion and associated illnesses such as atopic dermatitis, eczema, and psoriasis, as well as the emergence of non-melanoma cancer.PMID:38127818 | DOI:10.1080/15569527.2023.2295843 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 21, 2023 Category: Toxicology Authors: Shakilur Rahman Rizwanul Haque Sheikh Raisuddin Source Type: research
Ocular irritation reversibility assessment of a laundry detergent using the Porcine Corneal Opacity Reversibility Assay (PorCORA): a focused study
Cutan Ocul Toxicol. 2023 Dec 15:1-12. doi: 10.1080/15569527.2023.2284146. Online ahead of print.ABSTRACTConsumer product manufacturers utilise a spectrum of alternative ocular irritation assays, as these tests do not require the use of live animals. Despite their usefulness, no regulatory-accepted assay assesses the reversibility of ocular damage, a key criterion of GHS ocular classification, like the rabbit eye test (i.e., Draize Rabbit Eye Test [DRET]) . The Porcine Corneal Opacity Reversibility Assay (PorCORA), an ex vivo intact corneal tissue culture model, predicts the reversibility of damage by ocular irritants. Incl...
Source: Cutaneous and Ocular Toxicology - December 15, 2023 Category: Toxicology Authors: Puneet Vij Ashley Brinkman Rachael M Koch George DeGeorge Matthew Wolter Source Type: research
Ocular irritation reversibility assessment of a laundry detergent using the Porcine Corneal Opacity Reversibility Assay (PorCORA): a focused study
Cutan Ocul Toxicol. 2023 Dec 15:1-12. doi: 10.1080/15569527.2023.2284146. Online ahead of print.ABSTRACTConsumer product manufacturers utilise a spectrum of alternative ocular irritation assays, as these tests do not require the use of live animals. Despite their usefulness, no regulatory-accepted assay assesses the reversibility of ocular damage, a key criterion of GHS ocular classification, like the rabbit eye test (i.e., Draize Rabbit Eye Test [DRET]) . The Porcine Corneal Opacity Reversibility Assay (PorCORA), an ex vivo intact corneal tissue culture model, predicts the reversibility of damage by ocular irritants. Incl...
Source: Cutaneous and Ocular Toxicology - December 15, 2023 Category: Toxicology Authors: Puneet Vij Ashley Brinkman Rachael M Koch George DeGeorge Matthew Wolter Source Type: research
Ocular irritation reversibility assessment of a laundry detergent using the Porcine Corneal Opacity Reversibility Assay (PorCORA): a focused study
Cutan Ocul Toxicol. 2023 Dec 15:1-12. doi: 10.1080/15569527.2023.2284146. Online ahead of print.ABSTRACTConsumer product manufacturers utilise a spectrum of alternative ocular irritation assays, as these tests do not require the use of live animals. Despite their usefulness, no regulatory-accepted assay assesses the reversibility of ocular damage, a key criterion of GHS ocular classification, like the rabbit eye test (i.e., Draize Rabbit Eye Test [DRET]) . The Porcine Corneal Opacity Reversibility Assay (PorCORA), an ex vivo intact corneal tissue culture model, predicts the reversibility of damage by ocular irritants. Incl...
Source: Cutaneous and Ocular Toxicology - December 15, 2023 Category: Toxicology Authors: Puneet Vij Ashley Brinkman Rachael M Koch George DeGeorge Matthew Wolter Source Type: research
Ocular irritation reversibility assessment of a laundry detergent using the Porcine Corneal Opacity Reversibility Assay (PorCORA): a focused study
Cutan Ocul Toxicol. 2023 Dec 15:1-12. doi: 10.1080/15569527.2023.2284146. Online ahead of print.ABSTRACTConsumer product manufacturers utilise a spectrum of alternative ocular irritation assays, as these tests do not require the use of live animals. Despite their usefulness, no regulatory-accepted assay assesses the reversibility of ocular damage, a key criterion of GHS ocular classification, like the rabbit eye test (i.e., Draize Rabbit Eye Test [DRET]) . The Porcine Corneal Opacity Reversibility Assay (PorCORA), an ex vivo intact corneal tissue culture model, predicts the reversibility of damage by ocular irritants. Incl...
Source: Cutaneous and Ocular Toxicology - December 15, 2023 Category: Toxicology Authors: Puneet Vij Ashley Brinkman Rachael M Koch George DeGeorge Matthew Wolter Source Type: research
