Current Treatment Options in Cardiovascular Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Advanced Heart Failure Therapies: Specific Considerations for Cardio-Oncology Patients
AbstractPurpose of ReviewHeart failure and cancer share common risk factors. We sought to describe outcomes of advanced heart failure therapies in the cardio-oncology population.Recent FindingsStudies specific to outcomes in patients with either active cancer or chemotherapy-induced cardiomyopathy (CCMP) are limited. Despite this, studies on highly selected cohorts have suggested similar outcomes after heart transplant in those with and without a history of cancer. Conversely, data regarding heart transplant in CCMP have shown mixed outcomes with similar or worse survival. Left ventricular assist device appears to confer s...
Source: Current Treatment Options in Cardiovascular Medicine - September 6, 2022 Category: Cardiology Source Type: research

Strategies for Cardio-Oncology Care During the COVID-19 Pandemic
AbstractPurpose of reviewThe COVID-19 pandemic has disrupted healthcare and has disproportionately affected the marginalized populations. Patients with cancer and cardiovascular disease (cardio-oncology population) are uniquely affected. In this review, we explore the current data on COVID-19 vulnerability and outcomes in these patients and discuss strategies for cardio-oncology care with a focus on healthcare innovation, health equity, and inclusion.Recent findingsThe growing evidence suggest increased morbidity and mortality from COVID-19 in patients with comorbid cancer and cardiovascular disease. Additionally, de novo ...
Source: Current Treatment Options in Cardiovascular Medicine - September 6, 2022 Category: Cardiology Source Type: research

Primary Prevention Implantable Cardioverter-Defibrillators in Ischemic Cardiomyopathy
AbstractPurpose of reviewImplantable cardiac defibrillators have been utilised in ischemic cardiomyopathy patients, in a primary prevention capacity since 1996. The early trials utilised electrophysiology studies to identify high-risk individuals, but contemporary imaging modalities were not widely available when these trials were conducted.Recent findingsThis review assess evidence from previous trials, which contributed to the formulation of current guidelines. There is data demonstrating ventricular arrhythmias occurring in individuals that were not initially eligible for implantable cardiac defibrillators. We investiga...
Source: Current Treatment Options in Cardiovascular Medicine - July 11, 2022 Category: Cardiology Source Type: research

Racial and Ethnic Disparities in the Treatment of Aortic Stenosis: Current Challenges and Future Strategies for Achieving Equity in Care
AbstractPurpose of reviewAortic stenosis (AS) is associated with high morbidity and mortality. Despite the growing prevalence of AS among an aging and increasingly diverse population, racial minorities remain underrepresented in the treatment of severe AS. This review highlights racial and ethnic disparities in the management of AS, associated barriers limiting access to care, and proposed solutions to combat these findings.Recent findingsAortic stenosis appears to be less prevalent among racial and ethnic minorities. Despite these findings, they experience significant disparities in the management of AS. Minorities are le...
Source: Current Treatment Options in Cardiovascular Medicine - April 20, 2022 Category: Cardiology Source Type: research

COVID-19 and Cardiac Arrhythmias: a Contemporary Review
AbstractPurpose of ReviewA significant proportion of patients infected by the severe acute respiratory syndrome-coronavirus (SARS-CoV2) (COVID-19) also have disorders affecting the cardiac rhythm. In this review, we provide an in-depth review of the pathophysiological mechanisms underlying the associated arrhythmic complications of COVID-19 infection and provide pragmatic, evidence-based recommendations for the clinical management of these conditions.Recent FindingsArrhythmic manifestations of COVID-19 include atrial arrhythmias such as atrial fibrillation or atrial flutter, sinus node dysfunction, atrioventricular conduct...
Source: Current Treatment Options in Cardiovascular Medicine - April 19, 2022 Category: Cardiology Source Type: research

Malignant Mitral Valve Prolapse: Risk and Prevention of Sudden Cardiac Death
AbstractPurpose of ReviewThe purpose of this review is to explore the prevalence and risk factors for a malignant phenotype in mitral valve prolapse (MVP) characterized by life-threatening ventricular arrhythmias and sudden cardiac arrest and death (SCD), including mechanistic and pathophysiologic findings and mechanism-based potential therapies.Recent FindingsA malignant phenotype in MVP characterized by life-threatening arrhythmias has long been recognized, although MVP is often benign. Efforts to identify this malignant phenotype have revealed potential risk factors for SCD that include elongated, myxomatous leaflets, E...
Source: Current Treatment Options in Cardiovascular Medicine - March 22, 2022 Category: Cardiology Source Type: research

Anti-tachycardia Pacing: Mechanism, History and Contemporary Implementation
AbstractPurpose of ReviewImplantable cardioverter-defibrillator (ICD) shocks, whether appropriate or inappropriate, are associated with significant morbidity and mortality. Anti-tachycardia pacing (ATP) is a painless treatment for reentrant ventricular tachycardia (VT), and it has been shown to be effective for treating fast VT with low risk of acceleration or syncope. Yet there is substantial difference in the frequency, rate, and mechanism of VT in ICD recipients implanted for primary versus secondary prevention indications and the benefit of ATP differs accordingly. We review the mechanism of ATP, the history of ATP t...
Source: Current Treatment Options in Cardiovascular Medicine - March 1, 2022 Category: Cardiology Source Type: research

Percutaneous Left Atrial Appendage Closure: Review of Anatomy, Imaging, and Outcomes
AbstractPurpose of reviewPercutaneous left atrial appendage closure (LAAC) with WATCHMAN (Boston Scientific Inc.) has emerged as a viable non-pharmacological alternative for stroke prevention in several randomized clinical trials in high-risk AF patients with relative and absolute contraindications to anticoagulation. Several considerations include the proper selection of the patients, type of device, the antithrombotic therapy, and their duration post-procedurally.Recent findingsThe WATCHMAN device and the recently FDA-approved Abbott Amplatzer Amulet for stroke prevention in AF have shown satisfactory outcomes in stroke ...
Source: Current Treatment Options in Cardiovascular Medicine - March 1, 2022 Category: Cardiology Source Type: research

Diagnostic Pacing Maneuvers for Supraventricular Tachycardia Discrimination: a Taxonomic Approach
AbstractPurpose of reviewTo provide a taxonomy for grouping diagnostic maneuvers during an electrophysiology study for supraventricular tachycardia into mechanistic groups.Recent findingsAlthough many diagnostic maneuvers have been described, most rely on a core group of electrophysiologic principles. The taxonomy presented in this review builds around those core principles.SummaryUnderstanding diagnostic electrophysiology maneuvers in the context of underlying core mechanism can make it easier to learn and apply the maneuvers in clinical practice. (Source: Current Treatment Options in Cardiovascular Medicine)
Source: Current Treatment Options in Cardiovascular Medicine - February 24, 2022 Category: Cardiology Source Type: research