Current Opinion in Obstetrics and Gynecology 
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Comprehensive review of pelvic congestion syndrome: causes, symptoms, treatment options
Purpose of review
The purpose of this publication is to review the currently available and most up-to-date information regarding the pathogenesis, diagnosis, and treatment of pelvic congestion syndrome.
Recent findings
The diagnosis of pelvic congestion syndrome is difficult to make; however, it should remain on the differential for chronic pelvic pain. The most recent available research seems to favour endovascular treatment with interventional radiology over surgical management, with high success rate and low occurrence of complications.
Summary
High-level evidence on the diagnosis and management of pelvic conges...
Source: Current Opinion in Obstetrics and Gynecology - July 30, 2020 Category: OBGYN Tags: MINIMALLY INVASIVE GYNECOLOGIC PROCEDURES: Edited by Matthew T. Siedhoff and Nisse V. Clark Source Type: research
Editorial introductions
No abstract available (Source: Current Opinion in Obstetrics and Gynecology)
Source: Current Opinion in Obstetrics and Gynecology - July 30, 2020 Category: OBGYN Tags: EDITORIAL INTRODUCTIONS Source Type: research
Impact of underlying stress in infertility
Purpose of review
To review the latest findings about the impact of women's physiological stress on fertility treatment outcomes and the main biomarkers used.
Recent findings
Women with infertility report high levels of distress that can impact their treatment outcome. The combination of multiple methodologies in psychological stress evaluation result in higher validity, precision and richness in the data. Hair cortisol levels seem to be a promising biomarker to be associated to treatment outcomes.
Summary
The impact of distress on treatment outcome can be assessed with the help of biomarkers. Decreasing burden of ...
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Preconception diet, fertility, and later health in pregnancy
This article summarizes recent literature assessing preconception dietary intake and the association with fertility, time to pregnancy, and also the relationship with polycystic ovary syndrome and gestational diabetes; these conditions associate with each other, and also with infertility. The impact of paternal diet is also reported.
Summary
There is recent interest investigating diet and time to pregnancy, suggesting higher intakes of fruit, minimal intake of fast food and sugar sweetened beverages, and a diet lower in glycemic load, may improve time to pregnancy. There is minimal recent literature on paternal diet and...
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Anti-Müllerian hormone as a qualitative marker – or just quantity?
Purpose of review
In this review, we will summarize research looking into anti-Müllerian hormone (AMH) as a measure of oocyte quality.
Recent findings
AMH is a key factor involved in embryogenesis but also in the development of early follicles. Owing to its relatively small inter and intracycle variability, it has become a widely used method of ovarian reserve testing. In the realm of assisted reproductive technology, it has demonstrated a reliable ability to gauge the number of oocytes obtained during an in-vitro fertilization cycle. For these purposes, AMH is a readily measured quantitative tool. However, its quali...
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Frozen embryo transfer and preeclampsia: where is the link?
This article provides a review of frozen embryo transfer and available protocols, the highest incidence of gestational hypertensive disorders presented by the infertile population and an overview of the possible impact of the absence of corpus luteum on the genesis of this disease. (Source: Current Opinion in Obstetrics and Gynecology)
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Mitochondrial function in women with polycystic ovary syndrome
Purpose of review
To provide an overview of mitochondrial functional alterations in women with polycystic ovary syndrome (PCOS).
Recent findings
Although numerous studies have focused on PCOS, the pathophysiological mechanisms that cause this common disease remain unclear. Mitochondria play a central role in energy production, and mitochondrial dysfunction may underlie several abnormalities observed in women with PCOS. Recent studies associated mtDNA mutations and low mtDNA copy number with PCOS, and set out to characterize the potential protective role of mitochondrial and endoplasmic reticulum unfolded protein respo...
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Determining diagnostic criteria and cause of recurrent implantation failure
Purpose of review
Recurrent implantation failure (RIF) refers to the absence of implantation after repeated transfer of good embryos into a normal uterus. This review discusses the diagnostic criteria and cause of RIF.
Recent findings
Regardless of the advancements in IVF practice, RIF is still a challenge that has to be solved. Exact definition of RIF is lacking today. For the initial evaluation, a rigorous algorithmic evaluation should be compromised with an individualized principle. Factors that might affect the number and quality of the oocyte and sperm cells should be investigated in order to obtain a good-qualit...
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Oocyte activation, oolemma piercing, and real-time viability confirmation in human oocytes using electrophysiological techniques
We describe the potential clinical applications and their advantages such as creation of reliable automated cell injection systems and novel manual intracytoplasmic sperm injection (ICSI) training platforms. We also discuss theoretical adverse effects and ways to mitigate them. (Source: Current Opinion in Obstetrics and Gynecology)
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Testing the endometrium: is there enough evidence to justify clinical use?
Purpose of review
Embryo implantation remains the limiting factor in assisted reproduction outcomes. To date research has mainly focused on improving embryo quality, numbers and selection as the route to improve treatment results. However, with success rates plateauing, interest in the possibility of modulating the endometrial factor is increasing, and a number of biomarkers are now available that offer the possibility of assessing endometrial function.
Recent findings
In this review, we review recent evidence for the efficacy of a number of these biomarkers, with emphasis on those that aim to enable improvement in em...
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Extracellular vesicles as a potential diagnostic tool in assisted reproduction
Purpose of review
Extracellular vesicles have emerged as a promising field of research for their potential to serve as biomarkers. In the pathophysiology of reproduction, they have attracted significant attention because of their diverse roles in gametogenesis and embryo-endometrial cross-talk. Advances in extracellular vesicle translational potential are herein reviewed with a particular focus in oocyte competence, semen quality diagnostics, embryo selection and detection of endometrial receptivity.
Recent findings
Specific miRNAs present in follicular fluid-derived extracellular vesicles have been associated with fo...
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
The vaginal microbiome as a tool to predict IVF success
Purpose of review
Herein, we present an overview of the recent microbiome research and findings within the field of reproductive medicine and its relation with the outcome of Assisted reproductive technology (ART). Analyses of the microbiome composition all throughout the female reproductive trace during the process of assisted reproductive techniques are discussed.
Recent findings
Only the vaginal microbiome can be sampled without possible risks of contamination. Although this also seems to apply to the cervical microbiome, collection has to be performed with extreme caution. Because of the high risk of cross contami...
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Editorial: Challenges in ART diagnostics
No abstract available (Source: Current Opinion in Obstetrics and Gynecology)
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. García Velasco Source Type: research
Editorial introductions
No abstract available (Source: Current Opinion in Obstetrics and Gynecology)
Source: Current Opinion in Obstetrics and Gynecology - May 7, 2020 Category: OBGYN Tags: EDITORIAL INTRODUCTIONS Source Type: research
Hysteroscopic endometrial resection vs. hysterectomy for abnormal uterine bleeding: impact on quality of life and sexuality. Evidence from a systematic review of randomized controlled trials
Purpose of review
The aim of this systematic review is to summarize the current evidence regarding the effectiveness of hysterectomy and hysteroscopic endometrial resection in improving quality of life (QoL), sexual function and psychological wellbeing of women abnormal uterine bleeding.
Recent findings
We performed a systematic literature search in PubMed/MEDLINE and Embase for original studies written in English (registered in PROSPERO 2019 CRD42019133632), using the terms ‘endometrial ablation’, ‘endometrial destruction’, ‘endometrial resection’, ‘hysterectomy’, ‘menorrhagia’, ‘dysfunctional u...
Source: Current Opinion in Obstetrics and Gynecology - March 3, 2020 Category: OBGYN Tags: SPECIAL COMMENTARY Source Type: research
