Dopaminergic Drugs and Valproate-associated Refractory Hyponatremia Over Levosulpiride-induced Parkinsonism in an Elderly Female Patient When Deprescribing was the Only Therapy
CONCLUSION: The case highlights the need to be vigilant for adverse consequences of the prescribing cascade, especially for antiemetic drugs, such as levosulpiride, because of its propensity to induce extrapyramidal reactions in older patients. In cases of refractory hyponatremia, a trial of de-challenge of valproate and dopaminergic drugs should be considered. In addition, the identification and removal of the culprit drugs can rescue the patient from a disabling cycle of adverse drug reactions.PMID:38523545 | DOI:10.2174/0115748863288106240313042127 (Source: Current Drug Safety)
Source: Current Drug Safety - March 25, 2024 Category: Drugs & Pharmacology Authors: Amol Dehade Sankha Shubhra Chakrabarti Not Taruni Srija Reddy Upinder Kaur Source Type: research
Dopaminergic Drugs and Valproate-associated Refractory Hyponatremia Over Levosulpiride-induced Parkinsonism in an Elderly Female Patient When Deprescribing was the Only Therapy
CONCLUSION: The case highlights the need to be vigilant for adverse consequences of the prescribing cascade, especially for antiemetic drugs, such as levosulpiride, because of its propensity to induce extrapyramidal reactions in older patients. In cases of refractory hyponatremia, a trial of de-challenge of valproate and dopaminergic drugs should be considered. In addition, the identification and removal of the culprit drugs can rescue the patient from a disabling cycle of adverse drug reactions.PMID:38523545 | DOI:10.2174/0115748863288106240313042127 (Source: Current Drug Safety)
Source: Current Drug Safety - March 25, 2024 Category: Drugs & Pharmacology Authors: Amol Dehade Sankha Shubhra Chakrabarti Not Taruni Srija Reddy Upinder Kaur Source Type: research
Dopaminergic Drugs and Valproate-associated Refractory Hyponatremia Over Levosulpiride-induced Parkinsonism in an Elderly Female Patient When Deprescribing was the Only Therapy
CONCLUSION: The case highlights the need to be vigilant for adverse consequences of the prescribing cascade, especially for antiemetic drugs, such as levosulpiride, because of its propensity to induce extrapyramidal reactions in older patients. In cases of refractory hyponatremia, a trial of de-challenge of valproate and dopaminergic drugs should be considered. In addition, the identification and removal of the culprit drugs can rescue the patient from a disabling cycle of adverse drug reactions.PMID:38523545 | DOI:10.2174/0115748863288106240313042127 (Source: Current Drug Safety)
Source: Current Drug Safety - March 25, 2024 Category: Drugs & Pharmacology Authors: Amol Dehade Sankha Shubhra Chakrabarti Not Taruni Srija Reddy Upinder Kaur Source Type: research
Dopaminergic Drugs and Valproate-associated Refractory Hyponatremia Over Levosulpiride-induced Parkinsonism in an Elderly Female Patient When Deprescribing was the Only Therapy
CONCLUSION: The case highlights the need to be vigilant for adverse consequences of the prescribing cascade, especially for antiemetic drugs, such as levosulpiride, because of its propensity to induce extrapyramidal reactions in older patients. In cases of refractory hyponatremia, a trial of de-challenge of valproate and dopaminergic drugs should be considered. In addition, the identification and removal of the culprit drugs can rescue the patient from a disabling cycle of adverse drug reactions.PMID:38523545 | DOI:10.2174/0115748863288106240313042127 (Source: Current Drug Safety)
Source: Current Drug Safety - March 25, 2024 Category: Drugs & Pharmacology Authors: Amol Dehade Sankha Shubhra Chakrabarti Not Taruni Srija Reddy Upinder Kaur Source Type: research
Dopaminergic Drugs and Valproate-associated Refractory Hyponatremia Over Levosulpiride-induced Parkinsonism in an Elderly Female Patient When Deprescribing was the Only Therapy
CONCLUSION: The case highlights the need to be vigilant for adverse consequences of the prescribing cascade, especially for antiemetic drugs, such as levosulpiride, because of its propensity to induce extrapyramidal reactions in older patients. In cases of refractory hyponatremia, a trial of de-challenge of valproate and dopaminergic drugs should be considered. In addition, the identification and removal of the culprit drugs can rescue the patient from a disabling cycle of adverse drug reactions.PMID:38523545 | DOI:10.2174/0115748863288106240313042127 (Source: Current Drug Safety)
Source: Current Drug Safety - March 25, 2024 Category: Drugs & Pharmacology Authors: Amol Dehade Sankha Shubhra Chakrabarti Not Taruni Srija Reddy Upinder Kaur Source Type: research
Hand Foot Syndrome Induced by Lenvatinib - A Case Report
CONCLUSION: Hand-foot syndrome is one of the commonest ADRs due to the use of lenvatinib. Lenvatinib is an oral formulation that patients can take at their homes. Hence, educating patients regarding the HFS is important so that they report it to the treating physicians on time. It is also essential to educate patients regarding the precautions to be taken to avoid hand-foot syndrome. This will help the physicians with the early discontinuation and appropriate treatment with corticosteroids, which will help in improving the quality of life of the patients already suffering from cancer.PMID:38486391 | DOI:10.2174/01157488632...
Source: Current Drug Safety - March 15, 2024 Category: Drugs & Pharmacology Authors: Kiran Rangshahi Siddhartha Nanda Meenalotchini Prakash Gurunthalingam Vikas Katiyara Pugazhenthan Thangaraju Nitin R Gaikwad Source Type: research
Hand Foot Syndrome Induced by Lenvatinib - A Case Report
CONCLUSION: Hand-foot syndrome is one of the commonest ADRs due to the use of lenvatinib. Lenvatinib is an oral formulation that patients can take at their homes. Hence, educating patients regarding the HFS is important so that they report it to the treating physicians on time. It is also essential to educate patients regarding the precautions to be taken to avoid hand-foot syndrome. This will help the physicians with the early discontinuation and appropriate treatment with corticosteroids, which will help in improving the quality of life of the patients already suffering from cancer.PMID:38486391 | DOI:10.2174/01157488632...
Source: Current Drug Safety - March 15, 2024 Category: Drugs & Pharmacology Authors: Kiran Rangshahi Siddhartha Nanda Meenalotchini Prakash Gurunthalingam Vikas Katiyara Pugazhenthan Thangaraju Nitin R Gaikwad Source Type: research
Hand Foot Syndrome Induced by Lenvatinib - A Case Report
CONCLUSION: Hand-foot syndrome is one of the commonest ADRs due to the use of lenvatinib. Lenvatinib is an oral formulation that patients can take at their homes. Hence, educating patients regarding the HFS is important so that they report it to the treating physicians on time. It is also essential to educate patients regarding the precautions to be taken to avoid hand-foot syndrome. This will help the physicians with the early discontinuation and appropriate treatment with corticosteroids, which will help in improving the quality of life of the patients already suffering from cancer.PMID:38486391 | DOI:10.2174/01157488632...
Source: Current Drug Safety - March 15, 2024 Category: Drugs & Pharmacology Authors: Kiran Rangshahi Siddhartha Nanda Meenalotchini Prakash Gurunthalingam Vikas Katiyara Pugazhenthan Thangaraju Nitin R Gaikwad Source Type: research
Hand Foot Syndrome Induced by Lenvatinib - A Case Report
CONCLUSION: Hand-foot syndrome is one of the commonest ADRs due to the use of lenvatinib. Lenvatinib is an oral formulation that patients can take at their homes. Hence, educating patients regarding the HFS is important so that they report it to the treating physicians on time. It is also essential to educate patients regarding the precautions to be taken to avoid hand-foot syndrome. This will help the physicians with the early discontinuation and appropriate treatment with corticosteroids, which will help in improving the quality of life of the patients already suffering from cancer.PMID:38486391 | DOI:10.2174/01157488632...
Source: Current Drug Safety - March 15, 2024 Category: Drugs & Pharmacology Authors: Kiran Rangshahi Siddhartha Nanda Meenalotchini Prakash Gurunthalingam Vikas Katiyara Pugazhenthan Thangaraju Nitin R Gaikwad Source Type: research
Hand Foot Syndrome Induced by Lenvatinib - A Case Report
CONCLUSION: Hand-foot syndrome is one of the commonest ADRs due to the use of lenvatinib. Lenvatinib is an oral formulation that patients can take at their homes. Hence, educating patients regarding the HFS is important so that they report it to the treating physicians on time. It is also essential to educate patients regarding the precautions to be taken to avoid hand-foot syndrome. This will help the physicians with the early discontinuation and appropriate treatment with corticosteroids, which will help in improving the quality of life of the patients already suffering from cancer.PMID:38486391 | DOI:10.2174/01157488632...
Source: Current Drug Safety - March 15, 2024 Category: Drugs & Pharmacology Authors: Kiran Rangshahi Siddhartha Nanda Meenalotchini Prakash Gurunthalingam Vikas Katiyara Pugazhenthan Thangaraju Nitin R Gaikwad Source Type: research
Hand Foot Syndrome Induced by Lenvatinib - A Case Report
CONCLUSION: Hand-foot syndrome is one of the commonest ADRs due to the use of lenvatinib. Lenvatinib is an oral formulation that patients can take at their homes. Hence, educating patients regarding the HFS is important so that they report it to the treating physicians on time. It is also essential to educate patients regarding the precautions to be taken to avoid hand-foot syndrome. This will help the physicians with the early discontinuation and appropriate treatment with corticosteroids, which will help in improving the quality of life of the patients already suffering from cancer.PMID:38486391 | DOI:10.2174/01157488632...
Source: Current Drug Safety - March 15, 2024 Category: Drugs & Pharmacology Authors: Kiran Rangshahi Siddhartha Nanda Meenalotchini Prakash Gurunthalingam Vikas Katiyara Pugazhenthan Thangaraju Nitin R Gaikwad Source Type: research
Hand Foot Syndrome Induced by Lenvatinib - A Case Report
CONCLUSION: Hand-foot syndrome is one of the commonest ADRs due to the use of lenvatinib. Lenvatinib is an oral formulation that patients can take at their homes. Hence, educating patients regarding the HFS is important so that they report it to the treating physicians on time. It is also essential to educate patients regarding the precautions to be taken to avoid hand-foot syndrome. This will help the physicians with the early discontinuation and appropriate treatment with corticosteroids, which will help in improving the quality of life of the patients already suffering from cancer.PMID:38486391 | DOI:10.2174/01157488632...
Source: Current Drug Safety - March 15, 2024 Category: Drugs & Pharmacology Authors: Kiran Rangshahi Siddhartha Nanda Meenalotchini Prakash Gurunthalingam Vikas Katiyara Pugazhenthan Thangaraju Nitin R Gaikwad Source Type: research
Hand Foot Syndrome Induced by Lenvatinib - A Case Report
CONCLUSION: Hand-foot syndrome is one of the commonest ADRs due to the use of lenvatinib. Lenvatinib is an oral formulation that patients can take at their homes. Hence, educating patients regarding the HFS is important so that they report it to the treating physicians on time. It is also essential to educate patients regarding the precautions to be taken to avoid hand-foot syndrome. This will help the physicians with the early discontinuation and appropriate treatment with corticosteroids, which will help in improving the quality of life of the patients already suffering from cancer.PMID:38486391 | DOI:10.2174/01157488632...
Source: Current Drug Safety - March 15, 2024 Category: Drugs & Pharmacology Authors: Kiran Rangshahi Siddhartha Nanda Meenalotchini Prakash Gurunthalingam Vikas Katiyara Pugazhenthan Thangaraju Nitin R Gaikwad Source Type: research
Assessment of Monitoring and Management Practices of Antipsychotic-Induced Hyperprolactinemia at a Medical City in Riyadh, Saudi Arabia: A Retrospective Cohort Study
CONCLUSION: It is imperative to conduct a baseline check of prolactin levels before commencing any antipsychotic therapy. Similarly, routine prolactin level monitoring is recommended regardless of symptoms in patients treated with antipsychotics with a possible prolactin-raising effect. Adherence to evidence-based treatment guidelines can improve patient quality of life and therapeutic compliance.PMID:38485677 | DOI:10.2174/0115748863280407240305070905 (Source: Current Drug Safety)
Source: Current Drug Safety - March 14, 2024 Category: Drugs & Pharmacology Authors: Zahra Hussain Alshabeeb Bashayr Alsuwayni Omar Alshargi Ahmed H Abdelazeem Source Type: research
Assessment of Monitoring and Management Practices of Antipsychotic-Induced Hyperprolactinemia at a Medical City in Riyadh, Saudi Arabia: A Retrospective Cohort Study
CONCLUSION: It is imperative to conduct a baseline check of prolactin levels before commencing any antipsychotic therapy. Similarly, routine prolactin level monitoring is recommended regardless of symptoms in patients treated with antipsychotics with a possible prolactin-raising effect. Adherence to evidence-based treatment guidelines can improve patient quality of life and therapeutic compliance.PMID:38485677 | DOI:10.2174/0115748863280407240305070905 (Source: Current Drug Safety)
Source: Current Drug Safety - March 14, 2024 Category: Drugs & Pharmacology Authors: Zahra Hussain Alshabeeb Bashayr Alsuwayni Omar Alshargi Ahmed H Abdelazeem Source Type: research
