Amphotericin-b-induced chronic kidney disease in a post-covid-19 patient with widespread rhinocerebral mucormycosis and pneumonia: A CASE REPORT
CONCLUSION: While COVID-19 has presented challenges and uncertainties, it has also provided valuable insights into the interactions between infectious agents and the human body. Continued research and vigilance are necessary to mitigate the impact of co-infections and improve outcomes for patients.PMID:37537934 | DOI:10.2174/1574886318666230804101539 (Source: Current Drug Safety)
Source: Current Drug Safety - August 4, 2023 Category: Drugs & Pharmacology Authors: Nishant Johri Ambika Choudhary Ujjawal Rawat Maheshwari Vengat Source Type: research

Enhancing the Efficiency of the Individual Case Safety Report (ICSR) Quality and Compliance through Automation
CONCLUSION: CMM tool enhanced the efficiency of both Retro-QC and late submission analyses by increasing productivity along with time and cost savings. It also reduced the number of errors, thereby enhancing the accuracy of the process and overall compliance.PMID:37533250 | DOI:10.2174/1574886318666230801162002 (Source: Current Drug Safety)
Source: Current Drug Safety - August 3, 2023 Category: Drugs & Pharmacology Authors: Shannon Link Adam Kammler Ritu Gupta Mahendra Hembade Retesh Kumar Vinu George Source Type: research

Enhancing the Efficiency of the Individual Case Safety Report (ICSR) Quality and Compliance through Automation
CONCLUSION: CMM tool enhanced the efficiency of both Retro-QC and late submission analyses by increasing productivity along with time and cost savings. It also reduced the number of errors, thereby enhancing the accuracy of the process and overall compliance.PMID:37533250 | DOI:10.2174/1574886318666230801162002 (Source: Current Drug Safety)
Source: Current Drug Safety - August 3, 2023 Category: Drugs & Pharmacology Authors: Shannon Link Adam Kammler Ritu Gupta Mahendra Hembade Retesh Kumar Vinu George Source Type: research

Dental Disorders Reported to the FDA Adverse Event Reporting System in Association with Buprenorphine: An Analysis by Ingredient Composition and Route of Administration
CONCLUSION: Subject to the limitations of spontaneous adverse event data, this study identified significantly disproportionate reporting of dental disorders to FAERS among patients treated with buprenorphine-containing medications, including formulations administered by sublingual, buccal and oral routes. These findings are consistent with prior data and suggest that regular oral care and proper dental hygiene be emphasized for patients undergoing therapy with orally dissolving buprenorphine.PMID:37526182 | DOI:10.2174/1574886318666230731151447 (Source: Current Drug Safety)
Source: Current Drug Safety - August 1, 2023 Category: Drugs & Pharmacology Authors: Richard H Woods Source Type: research

Dental Disorders Reported to the FDA Adverse Event Reporting System in Association with Buprenorphine: An Analysis by Ingredient Composition and Route of Administration
CONCLUSION: Subject to the limitations of spontaneous adverse event data, this study identified significantly disproportionate reporting of dental disorders to FAERS among patients treated with buprenorphine-containing medications, including formulations administered by sublingual, buccal and oral routes. These findings are consistent with prior data and suggest that regular oral care and proper dental hygiene be emphasized for patients undergoing therapy with orally dissolving buprenorphine.PMID:37526182 | DOI:10.2174/1574886318666230731151447 (Source: Current Drug Safety)
Source: Current Drug Safety - August 1, 2023 Category: Drugs & Pharmacology Authors: Richard H Woods Source Type: research

The Gambia death story: 66 children died!
Curr Drug Saf. 2023 Jul 26. doi: 10.2174/1574886318666230726161911. Online ahead of print.NO ABSTRACTPMID:37496139 | DOI:10.2174/1574886318666230726161911 (Source: Current Drug Safety)
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Sumel Ashique Source Type: research

Inappropriate use of proton pump inhibitor among elderly patients in British Columbia: what are the long-term adverse events?
CONCLUSION: This study revealed a high prevalence of PPI use among elderly populations in BC, Canada. The overutilization of PPIs is often a result of failure to re-evaluate the need for continuation of therapy. Published studies identified signals of serious harm from long-term PPI exposure. Healthcare providers with patients can reverse the relentless expansion of long-term PPI exposure by discussing the expected benefits and potential harms.PMID:37496243 | DOI:10.2174/1574886318666230726124540 (Source: Current Drug Safety)
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Mohamed Ben-Eltriki Manik Chhabra Alan Cassels James M Wright Source Type: research

Multiple sclerosis risk among anti-tumor necrosis factor alpha users: A methodological review of observational studies based on real-world data
This article demonstrates how cDAGs can be used to determine whether there is a confounder, a mediator or collider-stratification bias and when to adjust for them appropriately. We also use a case study to show how to control for potential biases by drawing a cDAG depicting anti-TNFαalpha; use and its potential to contribute to MS onset. Finally, we describe potential biases that might have led to contradictory results in previous studies that examined the effect of anti-TNFαalpha; and MS, including confounding, confounding by contraindication, and bias due to measurement error. Clinicians and researchers should be cogni...
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Lingyi Li Mahyar Etminan Gilaad G Kaplan Helen Tremlett Hui Xie J Antonio Avi ña-Zubieta Source Type: research

The Gambia death story: 66 children died!
Curr Drug Saf. 2023 Jul 26. doi: 10.2174/1574886318666230726161911. Online ahead of print.NO ABSTRACTPMID:37496139 | DOI:10.2174/1574886318666230726161911 (Source: Current Drug Safety)
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Sumel Ashique Source Type: research

Inappropriate use of proton pump inhibitor among elderly patients in British Columbia: what are the long-term adverse events?
CONCLUSION: This study revealed a high prevalence of PPI use among elderly populations in BC, Canada. The overutilization of PPIs is often a result of failure to re-evaluate the need for continuation of therapy. Published studies identified signals of serious harm from long-term PPI exposure. Healthcare providers with patients can reverse the relentless expansion of long-term PPI exposure by discussing the expected benefits and potential harms.PMID:37496243 | DOI:10.2174/1574886318666230726124540 (Source: Current Drug Safety)
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Mohamed Ben-Eltriki Manik Chhabra Alan Cassels James M Wright Source Type: research

Multiple sclerosis risk among anti-tumor necrosis factor alpha users: A methodological review of observational studies based on real-world data
This article demonstrates how cDAGs can be used to determine whether there is a confounder, a mediator or collider-stratification bias and when to adjust for them appropriately. We also use a case study to show how to control for potential biases by drawing a cDAG depicting anti-TNFαalpha; use and its potential to contribute to MS onset. Finally, we describe potential biases that might have led to contradictory results in previous studies that examined the effect of anti-TNFαalpha; and MS, including confounding, confounding by contraindication, and bias due to measurement error. Clinicians and researchers should be cogni...
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Lingyi Li Mahyar Etminan Gilaad G Kaplan Helen Tremlett Hui Xie J Antonio Avi ña-Zubieta Source Type: research

The Gambia death story: 66 children died!
Curr Drug Saf. 2023 Jul 26. doi: 10.2174/1574886318666230726161911. Online ahead of print.NO ABSTRACTPMID:37496139 | DOI:10.2174/1574886318666230726161911 (Source: Current Drug Safety)
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Sumel Ashique Source Type: research

Inappropriate use of proton pump inhibitor among elderly patients in British Columbia: what are the long-term adverse events?
CONCLUSION: This study revealed a high prevalence of PPI use among elderly populations in BC, Canada. The overutilization of PPIs is often a result of failure to re-evaluate the need for continuation of therapy. Published studies identified signals of serious harm from long-term PPI exposure. Healthcare providers with patients can reverse the relentless expansion of long-term PPI exposure by discussing the expected benefits and potential harms.PMID:37496243 | DOI:10.2174/1574886318666230726124540 (Source: Current Drug Safety)
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Mohamed Ben-Eltriki Manik Chhabra Alan Cassels James M Wright Source Type: research

Multiple sclerosis risk among anti-tumor necrosis factor alpha users: A methodological review of observational studies based on real-world data
This article demonstrates how cDAGs can be used to determine whether there is a confounder, a mediator or collider-stratification bias and when to adjust for them appropriately. We also use a case study to show how to control for potential biases by drawing a cDAG depicting anti-TNFαalpha; use and its potential to contribute to MS onset. Finally, we describe potential biases that might have led to contradictory results in previous studies that examined the effect of anti-TNFαalpha; and MS, including confounding, confounding by contraindication, and bias due to measurement error. Clinicians and researchers should be cogni...
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Lingyi Li Mahyar Etminan Gilaad G Kaplan Helen Tremlett Hui Xie J Antonio Avi ña-Zubieta Source Type: research

The Gambia death story: 66 children died!
Curr Drug Saf. 2023 Jul 26. doi: 10.2174/1574886318666230726161911. Online ahead of print.NO ABSTRACTPMID:37496139 | DOI:10.2174/1574886318666230726161911 (Source: Current Drug Safety)
Source: Current Drug Safety - July 27, 2023 Category: Drugs & Pharmacology Authors: Sumel Ashique Source Type: research