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Correction to: Molecular Imaging of Inflammation in Ischemic Heart Disease
The original version of this article unfortunately contained mistakes in the abbreviations and body of the text. The Authors had correctly pointed out these errors at the proof stage but were regretfully not implemented at the production level. (Source: Current Cardiovascular Imaging Reports)
Source: Current Cardiovascular Imaging Reports - May 16, 2018 Category: Radiology Source Type: research

Molecular Imaging of Inflammation in Ischemic Heart Disease
AbstractPurpose of ReviewIschemic heart disease is caused by atherosclerosis, the build-up of plaque in the coronary arteries, which can lead to the development of heart attacks and heart muscle damage. Despite the advent of medical and surgical therapy to prevent and treat atherosclerosis and its adverse clinical effects, ischemic heart disease remains a leading cause of morbidity and mortality. Recent studies have suggested that the immune system may play a greater role in the development of plaque rupture and adverse left ventricular remodeling after myocardial infarction. Understanding the molecular processes by which ...
Source: Current Cardiovascular Imaging Reports - April 26, 2018 Category: Radiology Source Type: research

Application of Artificial Intelligence in Coronary Computed Tomography Angiography
This article summarizes the currently available published literature with regard to the applications of artificial intelligence in cardiac computed tomography angiography.Recent FindingsRecent studies and emerging data demonstrate feasibility of artificial intelligence-based high-level image analysis and interpretation tools that will likely enable medical practitioners to achieve more accurate diagnosis of coronary artery disease. Emerging artificial intelligence-based computational modeling methods will assist with pre-operative planning for valve disease. Finally, early but significant work is also being performed in re...
Source: Current Cardiovascular Imaging Reports - April 20, 2018 Category: Radiology Source Type: research

Towards the Clinical Management of Cardiac Involvement in Systemic Inflammatory Conditions —a Central Role for CMR
AbstractPurpose of ReviewAnti-inflammatory therapies in systemic inflammatory diseases (SID) improve disease-associated disability and may also reduce cardiovascular events. Further optimization of treatment to directly target the inflammation affecting the cardiovascular system represents a potential goal of contemporary treatment. Yet, lack of non-invasive means to detect cardiovascular involvement and to monitor the response to treatment limit such advancements. This is also reflected in the recent 2017 ESC position paper on clinical management of cardiac involvement in SIDs, whose recommendations continue to rely on in...
Source: Current Cardiovascular Imaging Reports - April 7, 2018 Category: Radiology Source Type: research

Role of Cardiac Magnetic Resonance in Heart Failure with Preserved Ejection Fraction
AbstractPurpose of ReviewApproximately half of the patients presenting with heart failure have preserved ejection fraction. These patients usually have a combination of underlying etiologies and may profit from individualized treatment. Failure of clinical trials without adequate understanding of the underlying problem highlights the need for an in-depth assessment of this complex clinical syndrome. This review seeks to discuss the role of cardiovascular magnetic resonance imaging (CMR) in improving diagnosis and targeted management of heart failure with preserved ejection fraction (HFpEF).Recent FindingsTechnical advances...
Source: Current Cardiovascular Imaging Reports - March 23, 2018 Category: Radiology Source Type: research

Advanced Cardiovascular Magnetic Resonance Techniques in Grown-Up Congenital Heart Disease
AbstractPurposeCongenital heart diseases comprise a complex population in which functional and anatomic evaluation with cardiac magnetic resonance (CMR) acquires utmost importance in the decision-making process. The use of new CMR technologies can help us understand the physiopathology and improve risk stratification.Recent FindingsEfforts towards a better understanding of the processes that underlie the occurrence of adverse events in these patients, mainly heart failure and arrhythmia, have been made in the last years. Early identification of subclinical myocardial involvement by means of detection of changes at the cell...
Source: Current Cardiovascular Imaging Reports - February 24, 2018 Category: Radiology Source Type: research

Myocardial Salvage Imaging: Where Are We and Where Are We Heading? A Cardiac Magnetic Resonance Perspective
AbstractPurpose of ReviewCardiac magnetic resonance (CMR) has emerged in recent years as a reliable tool to assess, in a single examination after a reperfused myocardial infarction, the initially area at risk (AAR), the final infarct size (IS), and from their difference the salvaged myocardium (SM). The aim of the present review is to summarize recent advances in the CMR imaging of SM.Recent FindingsWhile there is consensus on the use of late gadolinium enhancement (LGE) to calculate IS, how to assess the AAR is a debated topic. The use of T2-weighted short-TI inversion recovery (T2W-STIR) is to date supported by a large a...
Source: Current Cardiovascular Imaging Reports - February 24, 2018 Category: Radiology Source Type: research

PET Imaging of Cardiac Hypoxia: Hitting Hypoxia Where It Hurts
We describe the lead hypoxia PET radiotracers currently in development and propose a rationale for how they should most appropriately be screened and validated.Recent FindingsWhile the majority of hypoxia imaging agents has been developed for oncology, the requirements for hypoxia imaging in cardiology are different. Recent work suggests that the bis(thiosemicarbazone) family of compounds may be capable of detecting the subtle degrees of hypoxia associated with cardiovascular syndromes, and that they have the potential to be “tuned” to provide different tracers for different applications.SummaryNew tracers currently in...
Source: Current Cardiovascular Imaging Reports - February 23, 2018 Category: Radiology Source Type: research

Molecular Imaging of Cardiac Sarcoidosis
AbstractPurpose of ReviewCardiac involvement is increasingly being recognized as a cause of significant morbidity and mortality in patients with sarcoidosis. Unfortunately, imaging cardiac sarcoidosis (CS) remains a challenge and often relies on advanced imaging modalities. The aim of this review is to provide an up-to-date overview of the role of molecular imaging for the diagnosis of cardiac sarcoidosis, with particular emphasis on the use of FDG and non-FDG PET.Recent FindingsIn the last few years, FDG-PET has established itself as an accurate imaging study for the assessment of CS. New diagnostic criteria have recently...
Source: Current Cardiovascular Imaging Reports - February 20, 2018 Category: Radiology Source Type: research