Creating the Future of (Endoluminal) GI Interventions
We describe the development of “hybrid” procedure rooms for GI interventions and rationale for their use. We also emphasize the importance of collaborating with interventional radiologists, software engineers, and data specialists. We predict major improvement in outcomes in both diagnosis and treatment will follow. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Clinics in Colon and Rectal Surgery)
Source: Clinics in Colon and Rectal Surgery - July 17, 2023 Category: Surgery Authors: Milsom, Jeffrey W. Pua, Bradley P. Sedrakyan, Art Lowenfeld, Lea Yeo, Heather L. Tags: Review Article Source Type: research

Barriers to Implementation of Advanced Endoscopic Procedures
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1770948Advanced endoscopy has been shown to be useful in the diagnosis and treatment of both benign and low-grade malignant colorectal lesions. In fact, advanced endoscopic procedures are being adopted as standard approaches to these lesions in many places around the world; however, their implementation in the United States has not been as widespread. We ascribe the difficulty in implementation to two reasons: (1) lack of advanced endoscopic training and (2) failure in reimbursement models as they relate to endoscopy. In this article, we hope to describe these barriers and inspire...
Source: Clinics in Colon and Rectal Surgery - July 17, 2023 Category: Surgery Authors: Gupta, Abhinav Wlodarczyk, Jordan Cologne, Kyle G. Tags: Review Article Source Type: research

Introduction to Endoluminal Surgery
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1770939 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Clinics in Colon and Rectal Surgery)
Source: Clinics in Colon and Rectal Surgery - July 17, 2023 Category: Surgery Authors: Abelson, Jonathan S. Tags: Preface Source Type: research

Introduction to the Guest EditorJonathan S. Abelson, MD, MS
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1770938 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Clinics in Colon and Rectal Surgery)
Source: Clinics in Colon and Rectal Surgery - July 17, 2023 Category: Surgery Authors: Steele, Scott R. Tags: Introduction to the Guest Editor Source Type: research

An Argument for State-Driven Quality Collaboratives
Clin Colon Rectal Surg 2023; 36: 287-289 DOI: 10.1055/s-0043-1768710 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Clinics in Colon and Rectal Surgery)
Source: Clinics in Colon and Rectal Surgery - May 22, 2023 Category: Surgery Authors: Kanters, Arielle Tags: Perspective Source Type: research

Screening and Management of Lynch Syndrome: The Chinese Experience
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1767706Lynch syndrome (LS), caused by germline mutations in the mismatch repair genes, is the most common hereditary colorectal cancer. While LS is also associated with various cancers, early detection of the proband is meaningful for tumor prevention, treatment, and familial management. It has been a dramatic shift on the screening approaches for LS. As the rapid development of the molecular biological methods, a comprehensive understanding of the LS screening strategies will help to improve the clinical care for this systematic disease. The current screening strategies have been...
Source: Clinics in Colon and Rectal Surgery - May 3, 2023 Category: Surgery Authors: Yu, Jiehai Ding, Pei-Rong Jiang, Wu Tags: Review Article Source Type: research

Cancer Risk of Peutz –Jeghers Syndrome and Treatment Experience: A Chinese Medical Center
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1767704Peutz–Jeghers syndrome (PJS), also known as hereditary mucocutaneous pigmented gastrointestinal polyposis, is a clinically rare autosomal dominant genetic disease, which falls into the category of hereditary colorectal cancer. There are ∼7,000 new cases of PJS in China every year, and 170,000 PJS patients may survive for a long time in society. PJS polyps are characterized by an early age of onset, difficult diagnosis and treatment, and easy recurrence. With repeated growth, polyps can lead to serious complications such as intestinal obstruction, intussusception, gastro...
Source: Clinics in Colon and Rectal Surgery - May 3, 2023 Category: Surgery Authors: Xu, Zuxin Gu, Guoli Tags: Review Article Source Type: research

Update on Surgical Management of FAP
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1767707Familial adenomatous polyposis (FAP) is an autosomal dominant disease caused by pathogenic germline adenomatous polyposis coli mutation, and characterized with multiple adenomas in the colon and the rectum. Various genetic variants have been confirmed to be associated with corresponding FAP phenotypes, which play important roles in the diagnosis and surgical treatment of FAP. Generally, proctocolectomy is recommended for FAP patients at the age of 20s. Exceptionally, for patients with attenuated FAP, high-risk of desmoid, chemoprevention therapy, or other circumstances, sur...
Source: Clinics in Colon and Rectal Surgery - April 17, 2023 Category: Surgery Authors: Zhang, Tianqi Xu, Ye Tags: Review Article Source Type: research

Update on Familial Adenomatous Polyposis-Associated Desmoid Tumors
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1767709Desmoid tumors (DT) represent the second high risk of tumor in familial adenomatous polyposis (FAP) patients. Although FAP-associated DTs (FAP-DT) are caused by germline mutations in the adenomatous polyposis coli (APC) gene, extracolonic manifestations, sex, family history, genotype, and the ileal pouch anal anastomosis procedure are all linked to the development of DTs in FAP patients. Multidisciplinary management has replaced aggressive surgery as the preferred treatment of DTs. There is growing evidence to support the use of active surveillance strategy as first-line tr...
Source: Clinics in Colon and Rectal Surgery - April 17, 2023 Category: Surgery Authors: Yang, Wanjun Ding, Pei-Rong Tags: Review Article Source Type: research

Application of Molecular Profiling in Colorectal Cancer Surgery
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1767702 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Clinics in Colon and Rectal Surgery)
Source: Clinics in Colon and Rectal Surgery - April 17, 2023 Category: Surgery Authors: Ding, Pei-Rong Tags: Preface Source Type: research

Impact of Molecular Status on Cytoreductive Surgery for Peritoneal Metastases from Colorectal Cancer
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1767705Colorectal cancer peritoneal metastases (CRC-PM) are present in 5 to 15% of instances of CRC, and the overall survival (OS) of patients with CRC-PM is much lower than that of patients with other isolated metastatic locations. In recent years, the introduction of cytoreductive surgery (CRS) in conjunction with hyperthermic intraperitoneal chemotherapy has resulted in a significant improvement in CRC-PM patients' OS. Despite this, a significant proportion of CRS patients continue to suffer complications of grades III to V or even die during the perioperative period. Early dia...
Source: Clinics in Colon and Rectal Surgery - April 16, 2023 Category: Surgery Authors: Zhong, Yun Yang, Keli Qin, Xiusen Luo, Rui Wang, Hui Tags: Review Article Source Type: research

The Quality Dilemma
Clin Colon Rectal Surg DOI: 10.1055/s-0043-57232 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: Clinics in Colon and Rectal Surgery)
Source: Clinics in Colon and Rectal Surgery - April 16, 2023 Category: Surgery Authors: Steele, Scott R. Tags: Review Article Source Type: research

Stage IV Colorectal Cancer at Initial Presentation versus Progression during and after Treatment, Differences in Management: Management Differences for Initial Presentation versus Progression of Disease after Initial Treatment
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1761626Stage IV colorectal cancer is a prevalent disease and understanding the appropriate treatment options is important. Medical oncologic treatment remains the mainstay of treatment in cases where curative resection is not possible. Surgical intervention is indicated if the primary tumor and associated metastases are amenable to curative resection or if obstructive, bleeding, or perforative complications arise from the tumor. New endoscopic techniques can provide palliation and benefit for patients who cannot undergo surgery and may speed time to chemotherapy initiation. Recent...
Source: Clinics in Colon and Rectal Surgery - April 16, 2023 Category: Surgery Authors: Monahan, Brian V. Patel, Takshaka Poggio, Juan Lucas Tags: Review Article Source Type: research

Organ Preservation in MSS Rectal Cancer
Clin Colon Rectal Surg DOI: 10.1055/s-0043-1767710Rectal cancer is a heterogeneous disease with complex genetic and molecular subtypes. Emerging progress of neoadjuvant therapy has led to increased pathological and clinical complete response (cCR) rates for microsatellite stable (MSS) rectal cancer, which responds poorly to immune checkpoint inhibitor alone. As a result, organ preservation of MSS rectal cancer as an alternative to radical surgery has gradually become a feasible option. For patients with cCR or near-cCR after neoadjuvant treatment, organ preservation can be implemented safely with less morbidity. Patient se...
Source: Clinics in Colon and Rectal Surgery - April 16, 2023 Category: Surgery Authors: Gao, Yuye Wu, Aiwen Tags: Review Article Source Type: research

The Progress of Colorectal Polyposis Syndrome in Chinese Population
This article mainly introduces the research progress and related work of colorectal polyposis syndrome in China. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Clinics in Colon and Rectal Surgery)
Source: Clinics in Colon and Rectal Surgery - April 9, 2023 Category: Surgery Authors: Yuan, Zhijun Yang, Mengyuan Yuan, Ying Tags: Review Article Source Type: research