Integration of Clinical and Molecular Features into Prediction Models for Outcomes in Endometrial Cancer
Endometrial cancer recurrence carries a poor prognosis. The rising incidence of endometrial cancer calls for improvements in treatment of advanced and recurrent diseases. Efforts have been made to molecularly characterize endometrial cancer with the goal of improving therapies. The study presented here describes the utilization of molecular features of endometrial cancer tumors that are likely to recur, along with clinical characteristics utilized together to predict recurrence. This work further studies recurrent endometrial cancers to group them into “clusters” based on the tumor’s molecular makeups with the ultima...
Source: Clinical Obstetrics and Gynecology - January 25, 2020 Category: OBGYN Tags: New and Novel Treatments for Gynecologic Cancer Source Type: research
Gynecologic Oncology: Challenges of Minimally Invasive Surgery In a Field of Maximal Complexities
Minimally invasive surgery has become a standard in the surgical treatment for many women with gynecologic cancers. Within the scope of minimally invasive surgery, several techniques exist. Here, we provide an overview of the challenging and controversial aspects of minimally invasive surgery in the field of gynecologic oncology, including single-site surgery, operating on morbidly obese patients, sentinel lymph node mapping, and recent trials and controversy of treating gynecologic cancer patients with a minimally invasive surgical approach. (Source: Clinical Obstetrics and Gynecology)
Source: Clinical Obstetrics and Gynecology - January 25, 2020 Category: OBGYN Tags: New and Novel Treatments for Gynecologic Cancer Source Type: research
Minimally Invasive Robotic Surgery for Gynecologic Cancers: A Review
This article reviews the current utilization of robotic surgery and its role for future treatment in gynecologic oncology. (Source: Clinical Obstetrics and Gynecology)
Source: Clinical Obstetrics and Gynecology - January 25, 2020 Category: OBGYN Tags: New and Novel Treatments for Gynecologic Cancer Source Type: research
Sentinel Lymph Nodes and Precision Surgery in Gynecologic Cancer
Besides histologic features, the presence of nodal metastasis is the most crucial prognostic factor for recurrence and survival for patients with gynecologic cancer. Conventionally, lymphadenectomy has been performed routinely to assess lymphatic metastasis. However, lymphadenectomy may be unnecessary in early-stage gynecologic cancer, because the percentage of patients with lymph node involvement is very low. The recent use of sentinel lymph node mapping has provided high feasibility, safety, and accuracy in the assessment of nodal metastasis. The National Comprehensive Cancer Network Clinical Practice Guidelines have inc...
Source: Clinical Obstetrics and Gynecology - January 25, 2020 Category: OBGYN Tags: New and Novel Treatments for Gynecologic Cancer Source Type: research
Updates in Cervical Cancer Treatment
Although rates of cervical cancer in the United States have been declining due to vaccination and screening efforts, it remains the fourth most common cancer in women worldwide and is still far from being eradicated, even in developed nations. This review discusses recent developments in cervical cancer treatment and reviews the literature supporting recent practice changes encompassing staging, surgical management, radiation, chemotherapy, targeted agents including immunotherapy, and imaging. (Source: Clinical Obstetrics and Gynecology)
Source: Clinical Obstetrics and Gynecology - January 25, 2020 Category: OBGYN Tags: New and Novel Treatments for Gynecologic Cancer Source Type: research
