Subcutaneous fat predicts bone metastasis in breast cancer: A novel multimodality-based deep learning model
CONCLUSION: Subcutaneous fat index could predict bone metastasis in BC patients. Deep learning multimodal algorithm demonstrates superior performance in assessing bone metastases in BC patients.PMID:38043007 | DOI:10.3233/CBM-230219 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - December 3, 2023 Category: Cancer & Oncology Authors: Shidi Miao Haobo Jia Wenjuan Huang Ke Cheng Wenjin Zhou Ruitao Wang Source Type: research

Correlation between IL3 signaling pathway-related genes and immune checkpoint inhibitor efficacy in patients with renal cell carcinoma
CONCLUSION: The IL3 pathway-related genes can be used as a predictor of the efficacy of ICIs in KIRC. The IL3 pathway-related genes may affect the therapeutic efficacy of ICIs by affecting the expression of immune-related molecules, immune cell infiltration, and the level of immune response pathways.PMID:38043008 | DOI:10.3233/CBM-230226 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - December 3, 2023 Category: Cancer & Oncology Authors: Shuang Hou Tianqi Gu Ying Shi Yushan Huang Jiarong Yao Peng Luo Manming Cao Jian Zhang Anqi Lin Weiliang Zhu Source Type: research

Integrative analysis of histone acetyltransferase KAT2A in human cancer
Cancer Biomark. 2023 Oct 24. doi: 10.3233/CBM-220464. Online ahead of print.ABSTRACTThe high incidence of mutations and the crucial roles of KAT2A in cancer development have received increased attention. Nevertheless, a systematic comparison of the heterogeneity and dynamics across different cancer types has not been conducted. Hence, a deep analysis using public databases was performed to clarify the contributions of KAT2A and its correlation with tumorigenesis. The raw data regarding KAT2A expression in cancer patients and healthy controls were obtained from The Cancer Genome Atlas (TCGA). Sexually dimorphic manner, geno...
Source: Cancer Biomarkers : Section A of Disease Markers - November 26, 2023 Category: Cancer & Oncology Authors: Hua Li Chun Li Lu-Zong Yang Ji Liu Source Type: research

The identification of N6-methyladenosine-related miRNAs predictive of hepatocellular carcinoma prognosis and immunotherapy efficacy
CONCLUSION: The clinical innovation is the use of m6A-miRNAs as biomarkers for predicting prognosis regarding immunotherapy response in HCC patients.PMID:38007640 | DOI:10.3233/CBM-230263 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - November 26, 2023 Category: Cancer & Oncology Authors: Renrui Zou Yaqian Liu Sangsang Qiu Ya Lu Yan Chen Hui Yu Hangju Zhu Wenbo Zhu Longbiao Zhu Jifeng Feng Jing Han Source Type: research

Integrative analysis of histone acetyltransferase KAT2A in human cancer
Cancer Biomark. 2023 Oct 24. doi: 10.3233/CBM-220464. Online ahead of print.ABSTRACTThe high incidence of mutations and the crucial roles of KAT2A in cancer development have received increased attention. Nevertheless, a systematic comparison of the heterogeneity and dynamics across different cancer types has not been conducted. Hence, a deep analysis using public databases was performed to clarify the contributions of KAT2A and its correlation with tumorigenesis. The raw data regarding KAT2A expression in cancer patients and healthy controls were obtained from The Cancer Genome Atlas (TCGA). Sexually dimorphic manner, geno...
Source: Cancer Biomarkers : Section A of Disease Markers - November 26, 2023 Category: Cancer & Oncology Authors: Hua Li Chun Li Lu-Zong Yang Ji Liu Source Type: research