Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?
Cancer Biomark. 2024 Feb 6. doi: 10.3233/CBM-230360. Online ahead of print.ABSTRACTPulmonary nodules are ubiquitously found on computed tomography (CT) imaging either incidentally or via lung cancer screening and require careful diagnostic evaluation and management to both diagnose malignancy when present and avoid unnecessary biopsy of benign lesions. To engage in this complex decision-making, clinicians must first risk stratify pulmonary nodules to determine what the best course of action should be. Recent developments in imaging technology, computer processing power, and artificial intelligence algorithms have yielded r...
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Roger Y Kim Source Type: research

KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification
CONCLUSION: Our findings confirmed that the KIAA1429/RXFP1 axis promotes NSCLC tumorigenesis. This is the first study to reveal the inhibitory function of RXFP1 in NSCLC via KIAA1429-mediated m6A-modification. These findings may help identify new biomarkers for targeted NSCLC therapy.PMID:38427468 | DOI:10.3233/CBM-230188 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Zhixiang Zhang Jipeng Guo Chongwen Gong Sai Wu Yanlei Sun Source Type: research

Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach
CONCLUSION: Among 8 hub genes, only the expression levels of VEGFA, LOX, CCND1, and EGF showed a unique expression pattern exclusively in ccRCC on compared to other type of cancers.PMID:38427469 | DOI:10.3233/CBM-230271 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Vinoth S Satheeswaran Balasubramanian Ekambaram Perumal Kirankumar Santhakumar Source Type: research

Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?
Cancer Biomark. 2024 Feb 6. doi: 10.3233/CBM-230360. Online ahead of print.ABSTRACTPulmonary nodules are ubiquitously found on computed tomography (CT) imaging either incidentally or via lung cancer screening and require careful diagnostic evaluation and management to both diagnose malignancy when present and avoid unnecessary biopsy of benign lesions. To engage in this complex decision-making, clinicians must first risk stratify pulmonary nodules to determine what the best course of action should be. Recent developments in imaging technology, computer processing power, and artificial intelligence algorithms have yielded r...
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Roger Y Kim Source Type: research

KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification
CONCLUSION: Our findings confirmed that the KIAA1429/RXFP1 axis promotes NSCLC tumorigenesis. This is the first study to reveal the inhibitory function of RXFP1 in NSCLC via KIAA1429-mediated m6A-modification. These findings may help identify new biomarkers for targeted NSCLC therapy.PMID:38427468 | DOI:10.3233/CBM-230188 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Zhixiang Zhang Jipeng Guo Chongwen Gong Sai Wu Yanlei Sun Source Type: research

Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach
CONCLUSION: Among 8 hub genes, only the expression levels of VEGFA, LOX, CCND1, and EGF showed a unique expression pattern exclusively in ccRCC on compared to other type of cancers.PMID:38427469 | DOI:10.3233/CBM-230271 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Vinoth S Satheeswaran Balasubramanian Ekambaram Perumal Kirankumar Santhakumar Source Type: research

Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?
Cancer Biomark. 2024 Feb 6. doi: 10.3233/CBM-230360. Online ahead of print.ABSTRACTPulmonary nodules are ubiquitously found on computed tomography (CT) imaging either incidentally or via lung cancer screening and require careful diagnostic evaluation and management to both diagnose malignancy when present and avoid unnecessary biopsy of benign lesions. To engage in this complex decision-making, clinicians must first risk stratify pulmonary nodules to determine what the best course of action should be. Recent developments in imaging technology, computer processing power, and artificial intelligence algorithms have yielded r...
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Roger Y Kim Source Type: research

KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification
CONCLUSION: Our findings confirmed that the KIAA1429/RXFP1 axis promotes NSCLC tumorigenesis. This is the first study to reveal the inhibitory function of RXFP1 in NSCLC via KIAA1429-mediated m6A-modification. These findings may help identify new biomarkers for targeted NSCLC therapy.PMID:38427468 | DOI:10.3233/CBM-230188 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Zhixiang Zhang Jipeng Guo Chongwen Gong Sai Wu Yanlei Sun Source Type: research

Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach
CONCLUSION: Among 8 hub genes, only the expression levels of VEGFA, LOX, CCND1, and EGF showed a unique expression pattern exclusively in ccRCC on compared to other type of cancers.PMID:38427469 | DOI:10.3233/CBM-230271 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Vinoth S Satheeswaran Balasubramanian Ekambaram Perumal Kirankumar Santhakumar Source Type: research

Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?
Cancer Biomark. 2024 Feb 6. doi: 10.3233/CBM-230360. Online ahead of print.ABSTRACTPulmonary nodules are ubiquitously found on computed tomography (CT) imaging either incidentally or via lung cancer screening and require careful diagnostic evaluation and management to both diagnose malignancy when present and avoid unnecessary biopsy of benign lesions. To engage in this complex decision-making, clinicians must first risk stratify pulmonary nodules to determine what the best course of action should be. Recent developments in imaging technology, computer processing power, and artificial intelligence algorithms have yielded r...
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Roger Y Kim Source Type: research

KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification
CONCLUSION: Our findings confirmed that the KIAA1429/RXFP1 axis promotes NSCLC tumorigenesis. This is the first study to reveal the inhibitory function of RXFP1 in NSCLC via KIAA1429-mediated m6A-modification. These findings may help identify new biomarkers for targeted NSCLC therapy.PMID:38427468 | DOI:10.3233/CBM-230188 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Zhixiang Zhang Jipeng Guo Chongwen Gong Sai Wu Yanlei Sun Source Type: research

Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach
CONCLUSION: Among 8 hub genes, only the expression levels of VEGFA, LOX, CCND1, and EGF showed a unique expression pattern exclusively in ccRCC on compared to other type of cancers.PMID:38427469 | DOI:10.3233/CBM-230271 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Vinoth S Satheeswaran Balasubramanian Ekambaram Perumal Kirankumar Santhakumar Source Type: research

Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?
Cancer Biomark. 2024 Feb 6. doi: 10.3233/CBM-230360. Online ahead of print.ABSTRACTPulmonary nodules are ubiquitously found on computed tomography (CT) imaging either incidentally or via lung cancer screening and require careful diagnostic evaluation and management to both diagnose malignancy when present and avoid unnecessary biopsy of benign lesions. To engage in this complex decision-making, clinicians must first risk stratify pulmonary nodules to determine what the best course of action should be. Recent developments in imaging technology, computer processing power, and artificial intelligence algorithms have yielded r...
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Roger Y Kim Source Type: research

KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification
CONCLUSION: Our findings confirmed that the KIAA1429/RXFP1 axis promotes NSCLC tumorigenesis. This is the first study to reveal the inhibitory function of RXFP1 in NSCLC via KIAA1429-mediated m6A-modification. These findings may help identify new biomarkers for targeted NSCLC therapy.PMID:38427468 | DOI:10.3233/CBM-230188 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Zhixiang Zhang Jipeng Guo Chongwen Gong Sai Wu Yanlei Sun Source Type: research

Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach
CONCLUSION: Among 8 hub genes, only the expression levels of VEGFA, LOX, CCND1, and EGF showed a unique expression pattern exclusively in ccRCC on compared to other type of cancers.PMID:38427469 | DOI:10.3233/CBM-230271 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - March 1, 2024 Category: Cancer & Oncology Authors: Vinoth S Satheeswaran Balasubramanian Ekambaram Perumal Kirankumar Santhakumar Source Type: research