Influence of < em > CYP2C19 < /em > , < em > CYP2D6 < /em > , and < em > ABCB1 < /em > Gene Variants and Serum Levels of Escitalopram and Aripiprazole on Treatment-Emergent Sexual Dysfunction: A Canadian Biomarker Integration Network in Depression 1 (CAN-BIND 1) Study
CONCLUSIONS: CYP2C19 metabolizer phenotypes may be influencing changes in sexual arousal related to ESC monotherapy. Thus, preemptive genotyping of CYP2C19 may help to guide selection of treatment that circumvents selective serotonin reuptake inhibitor-related sexual dysfunction thereby improving outcomes for patients. Additionally, further research is warranted to clarify the role of S-DCT in the mechanisms underlying ESC-related changes in SF and SS. This CAN-BIND-1 study was registered on clinicaltrials.gov (Identifier: NCT01655706) on 27 July 2012.PMID:37796764 | DOI:10.1177/07067437231203433 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - October 5, 2023 Category: Psychiatry Authors: Farhana Islam Leen Magarbeh Samar S M Elsheikh Stefan Kloiber Caroline W Espinola Venkat Bhat Benicio N Frey Roumen Milev Claudio N Soares Sagar V Parikh Franca Placenza Stefanie Hassel Valerie H Taylor Francesco Leri Pierre Blier Rudolf Uher Faranak Farz Source Type: research

Influence of < em > CYP2C19 < /em > , < em > CYP2D6 < /em > , and < em > ABCB1 < /em > Gene Variants and Serum Levels of Escitalopram and Aripiprazole on Treatment-Emergent Sexual Dysfunction: A Canadian Biomarker Integration Network in Depression 1 (CAN-BIND 1) Study
CONCLUSIONS: CYP2C19 metabolizer phenotypes may be influencing changes in sexual arousal related to ESC monotherapy. Thus, preemptive genotyping of CYP2C19 may help to guide selection of treatment that circumvents selective serotonin reuptake inhibitor-related sexual dysfunction thereby improving outcomes for patients. Additionally, further research is warranted to clarify the role of S-DCT in the mechanisms underlying ESC-related changes in SF and SS. This CAN-BIND-1 study was registered on clinicaltrials.gov (Identifier: NCT01655706) on 27 July 2012.PMID:37796764 | DOI:10.1177/07067437231203433 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - October 5, 2023 Category: Psychiatry Authors: Farhana Islam Leen Magarbeh Samar S M Elsheikh Stefan Kloiber Caroline W Espinola Venkat Bhat Benicio N Frey Roumen Milev Claudio N Soares Sagar V Parikh Franca Placenza Stefanie Hassel Valerie H Taylor Francesco Leri Pierre Blier Rudolf Uher Faranak Farz Source Type: research

Guide canadien sur l ’expertise et la rédaction de rapports en psychiatrie légale : résumé
Can J Psychiatry. 2023 Sep 28:7067437231200843. doi: 10.1177/07067437231200843. Online ahead of print.NO ABSTRACTPMID:37769295 | DOI:10.1177/07067437231200843 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 28, 2023 Category: Psychiatry Authors: Lisa A L Ramshaw Sumeeta Chatterjee Todd Tomita Graham D Glancy Treena D Wilkie Source Type: research

Guide canadien sur l ’expertise et la rédaction de rapports en psychiatrie légale : résumé
Can J Psychiatry. 2023 Sep 28:7067437231200843. doi: 10.1177/07067437231200843. Online ahead of print.NO ABSTRACTPMID:37769295 | DOI:10.1177/07067437231200843 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 28, 2023 Category: Psychiatry Authors: Lisa A L Ramshaw Sumeeta Chatterjee Todd Tomita Graham D Glancy Treena D Wilkie Source Type: research

Guide canadien sur l ’expertise et la rédaction de rapports en psychiatrie légale : résumé
Can J Psychiatry. 2023 Sep 28:7067437231200843. doi: 10.1177/07067437231200843. Online ahead of print.NO ABSTRACTPMID:37769295 | DOI:10.1177/07067437231200843 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 28, 2023 Category: Psychiatry Authors: Lisa A L Ramshaw Sumeeta Chatterjee Todd Tomita Graham D Glancy Treena D Wilkie Source Type: research

Guide canadien sur l ’expertise et la rédaction de rapports en psychiatrie légale : résumé
Can J Psychiatry. 2023 Sep 28:7067437231200843. doi: 10.1177/07067437231200843. Online ahead of print.NO ABSTRACTPMID:37769295 | DOI:10.1177/07067437231200843 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 28, 2023 Category: Psychiatry Authors: Lisa A L Ramshaw Sumeeta Chatterjee Todd Tomita Graham D Glancy Treena D Wilkie Source Type: research

Guide canadien sur l ’expertise et la rédaction de rapports en psychiatrie légale : résumé
Can J Psychiatry. 2023 Sep 28:7067437231200843. doi: 10.1177/07067437231200843. Online ahead of print.NO ABSTRACTPMID:37769295 | DOI:10.1177/07067437231200843 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 28, 2023 Category: Psychiatry Authors: Lisa A L Ramshaw Sumeeta Chatterjee Todd Tomita Graham D Glancy Treena D Wilkie Source Type: research

Guide canadien sur l ’expertise et la rédaction de rapports en psychiatrie légale : résumé
Can J Psychiatry. 2023 Sep 28:7067437231200843. doi: 10.1177/07067437231200843. Online ahead of print.NO ABSTRACTPMID:37769295 | DOI:10.1177/07067437231200843 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 28, 2023 Category: Psychiatry Authors: Lisa A L Ramshaw Sumeeta Chatterjee Todd Tomita Graham D Glancy Treena D Wilkie Source Type: research

Obstacles and practical perspectives of the consultation in general medicine of migrants with psychological disorders. Qualitative study among French general practitioners
CONCLUSION: This study highlights the difficulties encountered by general practitioner (GPs) dealing with migrant patients in France. They feel helpless in the face of the nature of the disorders encountered and experience a disparity between the connections that are difficult to establish and those in their usual practice, even when professional experience with this population is acquired. They point to the need for coordinated models of care, financed by public policy.PMID:37743560 | DOI:10.1177/07067437231200842 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 25, 2023 Category: Psychiatry Authors: Marie Lerigoleur Aur élie Urena-Dores Bourrel G érard Cyril Jaume Mathilde Minet Élodie Million Bernard Clary Agn ès Oude Engberink B éatrice Lognos Folco Source Type: research

Obstacles and practical perspectives of the consultation in general medicine of migrants with psychological disorders. Qualitative study among French general practitioners
CONCLUSION: This study highlights the difficulties encountered by general practitioner (GPs) dealing with migrant patients in France. They feel helpless in the face of the nature of the disorders encountered and experience a disparity between the connections that are difficult to establish and those in their usual practice, even when professional experience with this population is acquired. They point to the need for coordinated models of care, financed by public policy.PMID:37743560 | DOI:10.1177/07067437231200842 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 25, 2023 Category: Psychiatry Authors: Marie Lerigoleur Aur élie Urena-Dores Bourrel G érard Cyril Jaume Mathilde Minet Élodie Million Bernard Clary Agn ès Oude Engberink B éatrice Lognos Folco Source Type: research

Obstacles and practical perspectives of the consultation in general medicine of migrants with psychological disorders. Qualitative study among French general practitioners
CONCLUSION: This study highlights the difficulties encountered by general practitioner (GPs) dealing with migrant patients in France. They feel helpless in the face of the nature of the disorders encountered and experience a disparity between the connections that are difficult to establish and those in their usual practice, even when professional experience with this population is acquired. They point to the need for coordinated models of care, financed by public policy.PMID:37743560 | DOI:10.1177/07067437231200842 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 25, 2023 Category: Psychiatry Authors: Marie Lerigoleur Aur élie Urena-Dores Bourrel G érard Cyril Jaume Mathilde Minet Élodie Million Bernard Clary Agn ès Oude Engberink B éatrice Lognos Folco Source Type: research

Obstacles and practical perspectives of the consultation in general medicine of migrants with psychological disorders. Qualitative study among French general practitioners
CONCLUSION: This study highlights the difficulties encountered by general practitioner (GPs) dealing with migrant patients in France. They feel helpless in the face of the nature of the disorders encountered and experience a disparity between the connections that are difficult to establish and those in their usual practice, even when professional experience with this population is acquired. They point to the need for coordinated models of care, financed by public policy.PMID:37743560 | DOI:10.1177/07067437231200842 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 25, 2023 Category: Psychiatry Authors: Marie Lerigoleur Aur élie Urena-Dores Bourrel G érard Cyril Jaume Mathilde Minet Élodie Million Bernard Clary Agn ès Oude Engberink B éatrice Lognos Folco Source Type: research

The Association Between Self-Reported Anxiety and Retention in Opioid Agonist Therapy: Findings From a Canadian Pragmatic Trial
CONCLUSIONS: Baseline anxiety severity did not significantly impact retention in OAT for adults with POUD, and there was no significant effect modification by OAT type. However, the overall retention rates were low, highlighting the need to develop new strategies to minimize the risk of attrition from treatment.CLINICAL TRIAL REGISTRATION: This study was registered in ClinicalTrials.gov (NCT03033732).PMID:37697811 | DOI:10.1177/07067437231194385 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 12, 2023 Category: Psychiatry Authors: Anees Bahji Gabriel Bastien Paxton Bach JinCheol Choi Bernard Le Foll Ron Lim Didier Jutras-Aswad M Eugenia Socias Source Type: research

The Association Between Self-Reported Anxiety and Retention in Opioid Agonist Therapy: Findings From a Canadian Pragmatic Trial
CONCLUSIONS: Baseline anxiety severity did not significantly impact retention in OAT for adults with POUD, and there was no significant effect modification by OAT type. However, the overall retention rates were low, highlighting the need to develop new strategies to minimize the risk of attrition from treatment.CLINICAL TRIAL REGISTRATION: This study was registered in ClinicalTrials.gov (NCT03033732).PMID:37697811 | DOI:10.1177/07067437231194385 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 12, 2023 Category: Psychiatry Authors: Anees Bahji Gabriel Bastien Paxton Bach JinCheol Choi Bernard Le Foll Ron Lim Didier Jutras-Aswad M Eugenia Socias Source Type: research

The Association Between Self-Reported Anxiety and Retention in Opioid Agonist Therapy: Findings From a Canadian Pragmatic Trial
CONCLUSIONS: Baseline anxiety severity did not significantly impact retention in OAT for adults with POUD, and there was no significant effect modification by OAT type. However, the overall retention rates were low, highlighting the need to develop new strategies to minimize the risk of attrition from treatment.CLINICAL TRIAL REGISTRATION: This study was registered in ClinicalTrials.gov (NCT03033732).PMID:37697811 | DOI:10.1177/07067437231194385 (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - September 12, 2023 Category: Psychiatry Authors: Anees Bahji Gabriel Bastien Paxton Bach JinCheol Choi Bernard Le Foll Ron Lim Didier Jutras-Aswad M Eugenia Socias Source Type: research