Ghrelin/GHSR Axis Induced M2 Macrophage and Alleviated Intestinal Barrier Dysfunction in a Sepsis Rat Model by Inactivating E2F1/NF- < em > κ < /em > B Signaling
Can J Gastroenterol Hepatol. 2023 Dec 29;2023:1629777. doi: 10.1155/2023/1629777. eCollection 2023.ABSTRACTSepsis is an inflammatory reaction disorder state that is induced by infection. The activation and regulation of the immune system play an essential role in the development of sepsis. Our previous studies have shown that ghrelin ameliorates intestinal dysfunction in sepsis. Very little is known about the mechanism of ghrelin and its receptor (GHSR) on the intestinal barrier and the immune function of macrophage regulation. Our research is to investigate the regulatory effect and molecular mechanism of the ghrelin/GHSR...
Source: Canadian Journal of Gastroenterology - January 8, 2024 Category: Gastroenterology Authors: Lei Zhu Zhimin Dou Wei Wu Qiliang Hou Sen Wang Ziqian Yuan Bin Li Jian Liu Source Type: research

Prevalence of Hepatitis B and Hepatitis C Viral Infections and Their Associated Factors among Diabetic Patients Visiting Debre Tabor Referral Hospital, Northwest Ethiopia, 2021: A Cross-Sectional Study
CONCLUSION: In this study, no association was obtained between sociodemographic, clinical, and behavioural factors and the prevalence of hepatitis B and C viruses. Furthermore, there is no significant association detected between HBV or potential HCV infection and DM. Despite these results, continuing professional training programs on HBV and HCV infection, including increased vaccination coverage rates for HBV, are required.PMID:38021268 | PMC:PMC10673667 | DOI:10.1155/2023/5077706 (Source: Canadian Journal of Gastroenterology)
Source: Canadian Journal of Gastroenterology - November 29, 2023 Category: Gastroenterology Authors: Debaka Belete Dessie Kassaw Tesfaye Andualem Source Type: research

Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Liver Failure Undergoing Plasma Exchange: A Single-Center Retrospective Study
CONCLUSION: Combined age with mean decrease rates of total bilirubin and MELD score as a novel and simple clinical predictor can accurately predict 90-day transplant-free mortality in adult patients with ALF undergoing PE, which is worthy of application and promotion in clinical practice, especially in the identification of potential transplant candidates.PMID:38021269 | PMC:PMC10645502 | DOI:10.1155/2023/6115499 (Source: Canadian Journal of Gastroenterology)
Source: Canadian Journal of Gastroenterology - November 29, 2023 Category: Gastroenterology Authors: Di Jin Kai Kang Bing-Zhu Yan Jian-Nan Zhang Jun-Bo Zheng Zhi-Hui Wang Di Wu Yu-Jia Tang Xin-Tong Wang Qi-Qi Lai Yang Cao Hong-Liang Wang Yang Gao Source Type: research

Prevalence of Hepatitis B and Hepatitis C Viral Infections and Their Associated Factors among Diabetic Patients Visiting Debre Tabor Referral Hospital, Northwest Ethiopia, 2021: A Cross-Sectional Study
CONCLUSION: In this study, no association was obtained between sociodemographic, clinical, and behavioural factors and the prevalence of hepatitis B and C viruses. Furthermore, there is no significant association detected between HBV or potential HCV infection and DM. Despite these results, continuing professional training programs on HBV and HCV infection, including increased vaccination coverage rates for HBV, are required.PMID:38021268 | PMC:PMC10673667 | DOI:10.1155/2023/5077706 (Source: Canadian Journal of Gastroenterology)
Source: Canadian Journal of Gastroenterology - November 29, 2023 Category: Gastroenterology Authors: Debaka Belete Dessie Kassaw Tesfaye Andualem Source Type: research

Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Liver Failure Undergoing Plasma Exchange: A Single-Center Retrospective Study
CONCLUSION: Combined age with mean decrease rates of total bilirubin and MELD score as a novel and simple clinical predictor can accurately predict 90-day transplant-free mortality in adult patients with ALF undergoing PE, which is worthy of application and promotion in clinical practice, especially in the identification of potential transplant candidates.PMID:38021269 | PMC:PMC10645502 | DOI:10.1155/2023/6115499 (Source: Canadian Journal of Gastroenterology)
Source: Canadian Journal of Gastroenterology - November 29, 2023 Category: Gastroenterology Authors: Di Jin Kai Kang Bing-Zhu Yan Jian-Nan Zhang Jun-Bo Zheng Zhi-Hui Wang Di Wu Yu-Jia Tang Xin-Tong Wang Qi-Qi Lai Yang Cao Hong-Liang Wang Yang Gao Source Type: research

Prevalence of Hepatitis B and Hepatitis C Viral Infections and Their Associated Factors among Diabetic Patients Visiting Debre Tabor Referral Hospital, Northwest Ethiopia, 2021: A Cross-Sectional Study
CONCLUSION: In this study, no association was obtained between sociodemographic, clinical, and behavioural factors and the prevalence of hepatitis B and C viruses. Furthermore, there is no significant association detected between HBV or potential HCV infection and DM. Despite these results, continuing professional training programs on HBV and HCV infection, including increased vaccination coverage rates for HBV, are required.PMID:38021268 | PMC:PMC10673667 | DOI:10.1155/2023/5077706 (Source: Canadian Journal of Gastroenterology)
Source: Canadian Journal of Gastroenterology - November 29, 2023 Category: Gastroenterology Authors: Debaka Belete Dessie Kassaw Tesfaye Andualem Source Type: research