Canadian Journal of Gastroenterology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Gambogic Acid Inhibits Gastric Cancer Cell Proliferation through Necroptosis
Can J Gastroenterol Hepatol. 2023 Aug 8;2023:7532367. doi: 10.1155/2023/7532367. eCollection 2023.ABSTRACTGambogic acid (GA) is a natural xanthonoid secreted by Garcinia hanburyi tree. It possesses anti-cancer activity in various types of cancers. In gastric cancer, it inhibits cell proliferation through increasing apoptosis. However, whether necroptosis is involved in the GA-induced proliferation inhibited in gastric cancer is unknown. In the present study, we found that RIPK1 specific inhibitor necrostatin-1 (Nec-1) attenuated GA-induced proliferation inhibition. GA treatment increased the phosphorylation of necroptosis-...
Source: Canadian Journal of Gastroenterology - August 17, 2023 Category: Gastroenterology Authors: Shujun Wang Yiping Wang Hui Zhu Miaohui Chen Liang Zhang Source Type: research

Platelet-to-Monocyte Ratio as a Novel Promising Agent for the Prognosis of Hepatitis B Virus-Associated Decompensated Cirrhosis
CONCLUSIONS: Our results demonstrate that low PMR may be an independent predictor of 30-day mortality in patients with HBV-DeCi, and combined with the MELD score, it may be useful to complement other conventional measures to enable effective management of these patients.PMID:37485072 | PMC:PMC10361825 | DOI:10.1155/2023/6646156 (Source: Canadian Journal of Gastroenterology)
Source: Canadian Journal of Gastroenterology - July 24, 2023 Category: Gastroenterology Authors: Jun Zhou Xin Li Min Wang Chunrong Gu Jingping Liu Source Type: research