Natural history of anti-PF4 antibodies in patients with vaccine-induced immune thrombocytopenia and thrombosis
Blood Transfus. 2024 Jan 29. doi: 10.2450/BloodTransfus.544. Online ahead of print.NO ABSTRACTPMID:38315531 | DOI:10.2450/BloodTransfus.544 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Elena Lotti Anna M Gori Martina Berteotti Angela Rogolino Francesca Cesari Daniela Poli Francesco Vannini Alessia Bertelli Betti Giusti Rossella Marcucci Source Type: research

Noninvasive fetal blood group antigen genotyping
Blood Transfus. 2024 Jan 29. doi: 10.2450/BloodTransfus.712. Online ahead of print.ABSTRACTNoninvasive fetal blood group antigen genotyping serves as a diagnostic tool to predict the risk of hemolytic disease of the fetus and newborn in pregnancies of immunized women. In addition, fetal RHD genotyping is used as an antenatal screening to guide targeted use of immunoglobulin prophylaxis in non-immunized RhD negative, pregnant women. Based on testing of cell-free DNA extracted from maternal plasma, these noninvasive assays demonstrate high performance accuracies. Consequently, noninvasive fetal blood group antigen genotyping...
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Frederik B Clausen C Ellen van der Schoot Source Type: research

The effects of pathogen reduction technology on apheresis platelet concentrates stored in PAS
DISCUSSION: The results of this study indicate that increased PSL induced by PRT treatment leads to a decreased in vitro platelet hemostatic efficacy and increased metabolic activity. However, the clinical impact of these alternations needs further investigation.PMID:38315533 | DOI:10.2450/BloodTransfus.600 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Stavros Tsalas Andreas G Tsantes Eleni Petrou Sofia Mellou Rozeta Sokou Electra Loukopoulou Anastasios G Kriebardis Sotirios P Fortis Dimitrios V Papadopoulos Aristeidis G Vaiopoulos Styliani Kokoris Argirios E Tsantes Source Type: research

Evaluation of an automated platelet aggregation method for detection of congenital or acquired platelet function defects
DISCUSSION: Thanks to this LTA technology, CS-2400, a routine coagulation analyzer widely available in routine laboratories, could prove useful for initial assessment of patients with a suspected PFD. Moreover, the PAL scores were a fairly accurate reflection of the platelet response to APT.PMID:38315534 | DOI:10.2450/BloodTransfus.601 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Anna Lecchi Marco Capecchi Lidia Padovan Andrea Artoni Nobuo Arai Sho Shinohara Silvia La Marca Flora Peyvandi Source Type: research

HLA class I expression on human platelets is highly variable and correlates with distinct allele group frequencies
DISCUSSION: Our data suggest an allele-dependent expression of HLA class I molecules on human platelets with distinct HLA allele group frequencies and different platelet subpopulation frequencies among blood donors.PMID:38315535 | DOI:10.2450/BloodTransfus.571 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Rocco Cantisani Valeria Del Re Francesca Toraldo Silvia Cantara Simone Pozzessere Giuseppe Marotta Adriano Spreafico Source Type: research