Development and evaluation of trigger tools to identify pediatric blood management errors
DISCUSSION: It is feasible to automatically detect pediatric PBM errors using existing data captured in the EHR that enable active surveillance systems. Over-transfusions may be one of the most frequent causes of harm in the pediatric environment.PMID:38557324 | DOI:10.2450/BloodTransfus.606 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Swaminathan Kandaswamy Cassandra D Josephson Margo R Rollins Jennifer Jones Patricia Zerra Ruchika Goel Jennifer Andrews Jeanne E Hendrickson Lani Lieberman Evan W Orenstein Source Type: research

Types of plasma exchange solution in the new scenario of thrombotic thrombocytopenic purpura treatment
Blood Transfus. 2024 Mar 4. doi: 10.2450/BloodTransfus.744. Online ahead of print.NO ABSTRACTPMID:38557325 | DOI:10.2450/BloodTransfus.744 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Nadia Garc ía Muñoz Sandra Ortega S ánchez Joan R Grifols Source Type: research

Patients with red cell antibodies: registries improve patient care by increasing patient safety, reducing costs, and enabling health information exchange
Blood Transfus. 2024 Mar 15. doi: 10.2450/BloodTransfus.753. Online ahead of print.NO ABSTRACTPMID:38557326 | DOI:10.2450/BloodTransfus.753 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Willy Albert Flegel Source Type: research

Thrombotic thrombocytopenic purpura: optimal management of plasma exchange, platelets and infection prevention
Blood Transfus. 2024 Mar 4. doi: 10.2450/BloodTransfus.710. Online ahead of print.NO ABSTRACTPMID:38557318 | DOI:10.2450/BloodTransfus.710 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Ingrid Parra-Salinas Juan Rodr íguez-García Saioa Zalba-Marcos Jos é A García-Erce Source Type: research

Why might cord blood be a better source of platelets for transfusion to neonates?
Blood Transfus. 2024 Mar 27. doi: 10.2450/BloodTransfus.566. Online ahead of print.ABSTRACTThrombocytopenia (defined as a platelet count <150×109/L) is a common condition in preterm neonates and may occur in 18-35% of all infants admitted to the Neonatal Intensive Care Unit (NICU). Neonatal platelet functionality in terms of reactivity is often described as reduced compared to adults, even in healthy, term neonates. However, this platelet "hyporeactivity" does not correspond to a global functional impairment of the normal delicately balanced neonatal hemostatic system. The extent to which neonatal thrombocytopenia and ...
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Valeria Cortesi Giacomo Cavallaro Genny Raffaeli Stefano Ghirardello Fabio Mosca Thomas R L Klei Suzanne Fustolo-Gunnink Simon Stanworth Helen V New Em öke Deschmann Enrico Lopriore Source Type: research

Identification of the novel c.300C & gt;G variation on the ABO*A1.02 allele associated with an A weak B phenotype
Blood Transfus. 2024 Feb 28. doi: 10.2450/BloodTransfus.642. Online ahead of print.NO ABSTRACTPMID:38557320 | DOI:10.2450/BloodTransfus.642 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Yuqing Shen Junshun Gong Yuyu Zhang Naizhu Su Lou Can Jiaming Li Dong Xiang Xiaohong Cai Hang Lei Source Type: research

A survey on the implementation of Patient Blood Management programs in Italy
DISCUSSION: The first national survey on the level of PBM implementation in Italy shows widespread adoption of diagnostic-therapeutic care pathways aimed at the diagnosis and treatment of anemia in the perioperative setting.PMID:38557321 | DOI:10.2450/BloodTransfus.724 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Vanessa Agostini Francesca Masiello Stefania Vaglio Eva Veropalumbo Ursula La Rocca Simonetta Pupella Vincenzo De Angelis Source Type: research

Platelet rich plasma for facial rejuvenation: an overview of systematic reviews
This article aims to review the literature and critically appraise the available evidence regarding the efficacy and safety of PRP for facial rejuvenation.MATERIAL AND METHODS: An overview of systematic reviews (SRs) of PRP use for facial rejuvenation. The methodological quality of the SRs was assessed using the AMSTAR-2 checklist; quality of the evidence from the trials included in each SR was appraised following the GRADE approach.RESULTS: Thirteen SRs published between 2015 and 2023, reporting data from 114 overlapping reports, based on 28 individual primary studies (18 uncontrolled reports), were included in this umbre...
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Mario Cruciani Francesca Masiello Ilaria Pati Simonetta Pupella Vincenzo De Angelis Source Type: research

Genomic characterisation of clinically significant blood group variants in Aboriginal Australians
In this study, we applied next-generation sequencing and analysis to 245 samples obtained from Aboriginal Australians from South-East Queensland, to predict antigen phenotypes for 36 blood group systems.RESULTS: We report potential weak antigens in blood group systems RH, FY and JR that have potential clinical implications in transfusion and pregnancy settings. These include partial DIII type 4, weak D type 33, and Del RHD (IVS2-2delA). The rare Rh phenotypes D+ C+ E+ c- e+ and D+ C+ E+ c+ e- were also detected.DISCUSSION: The comprehensive analyses of blood group genetic variant profiles identified in this study will prov...
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Sudhir Jadhao Candice Davison Eileen Roulis Simon Lee Tamika Campbell Reece Griffin Maree Toombs Alex Brown Maree Perry Bushra Nasir David O Irving Catherine A Hyland Robert L Flower Shivashankar H Nagaraj Source Type: research

Development and evaluation of trigger tools to identify pediatric blood management errors
DISCUSSION: It is feasible to automatically detect pediatric PBM errors using existing data captured in the EHR that enable active surveillance systems. Over-transfusions may be one of the most frequent causes of harm in the pediatric environment.PMID:38557324 | DOI:10.2450/BloodTransfus.606 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Swaminathan Kandaswamy Cassandra D Josephson Margo R Rollins Jennifer Jones Patricia Zerra Ruchika Goel Jennifer Andrews Jeanne E Hendrickson Lani Lieberman Evan W Orenstein Source Type: research

Types of plasma exchange solution in the new scenario of thrombotic thrombocytopenic purpura treatment
Blood Transfus. 2024 Mar 4. doi: 10.2450/BloodTransfus.744. Online ahead of print.NO ABSTRACTPMID:38557325 | DOI:10.2450/BloodTransfus.744 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Nadia Garc ía Muñoz Sandra Ortega S ánchez Joan R Grifols Source Type: research

Patients with red cell antibodies: registries improve patient care by increasing patient safety, reducing costs, and enabling health information exchange
Blood Transfus. 2024 Mar 15. doi: 10.2450/BloodTransfus.753. Online ahead of print.NO ABSTRACTPMID:38557326 | DOI:10.2450/BloodTransfus.753 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Willy Albert Flegel Source Type: research

A systematic review of indications when and how a military walking Blood Bank could bridge blood product unavailability
DISCUSSION: This unusual protocol needs to be integrated into the medical support plan until conventional transfusion support can take over, and should include on-site blood collection from a donor, whether a WBB or an emergency donor panel. The benefits of such a protocol outweigh the risks in a life-threatening situation, especially since these risks can be anticipated and minimised by planning to pre-screen all potential donors before their deployment. Finally, educating and training the staff who must implement this unusual procedure can also improve the safety and survival rate of future patients.PMID:38315529 | DOI:1...
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Julie Degueldre Emilie Dessy France T'Sas V éronique Deneys Source Type: research

Anti-CD38 monoclonal antibody impairs CD34+ mobilization and affects clonogenic potential in multiple myeloma patients
DISCUSSION: Our findings underscore the impact of daratumumab-based treatment on CD34+ mobilization in a real-life, upfront plerixafor-free population of NDMM patients. Higher probability of requiring multiple apheresis occurred among daratumumab-treated patients. Interestingly, the observation that daratumumab might negatively impact BFU-E colony formation, independent of CD34+ cell count, offers novel biological perspectives. Appropriate strategies should be adopted by the Apheresis teams to mitigate these potential negative effects.PMID:38315530 | DOI:10.2450/BloodTransfus.667 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Arianna Zappaterra Ivan Civettini Anna Maria Cafro Laura Pezzetti Silvia Pierini Michela Anghilieri Laura Bellio Paola Bertazzoni Giovanni Grillo Periana Minga Maria L Pioltelli Emanuele Ravano Marianna Sassone Clara V Vigan ò Elisabetta B Volpato Carlo Source Type: research

Natural history of anti-PF4 antibodies in patients with vaccine-induced immune thrombocytopenia and thrombosis
Blood Transfus. 2024 Jan 29. doi: 10.2450/BloodTransfus.544. Online ahead of print.NO ABSTRACTPMID:38315531 | DOI:10.2450/BloodTransfus.544 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Elena Lotti Anna M Gori Martina Berteotti Angela Rogolino Francesca Cesari Daniela Poli Francesco Vannini Alessia Bertelli Betti Giusti Rossella Marcucci Source Type: research