HLA class I expression on human platelets is highly variable and correlates with distinct allele group frequencies
DISCUSSION: Our data suggest an allele-dependent expression of HLA class I molecules on human platelets with distinct HLA allele group frequencies and different platelet subpopulation frequencies among blood donors.PMID:38315535 | DOI:10.2450/BloodTransfus.571 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Rocco Cantisani Valeria Del Re Francesca Toraldo Silvia Cantara Simone Pozzessere Giuseppe Marotta Adriano Spreafico Source Type: research

Establishment of a case registry that collaborates with a reference laboratory for blood group immunogenetics in Korea
Blood Transfus. 2023 Dec 19. doi: 10.2450/BloodTransfus.689. Online ahead of print.NO ABSTRACTPMID:38315536 | DOI:10.2450/BloodTransfus.689 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Dong Woo Shin Yun Ji Hong Kyoung Un Park Source Type: research

The role of erythropoietin to prevent red blood cell transfusion in a 2018-2020 two-center cohort of preterm infants
DISCUSSION: No benefit of rHu-EPO in preventing pRBCT was observed in our cohort. The place of rHu-EPO in future requires careful consideration of the population concerned, adjustment of the therapeutic schedule and evolution of the indications for pRBCT.PMID:38315537 | DOI:10.2450/BloodTransfus.641 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: No émie Bailly Roselyne Brat Geraldine Favrais Source Type: research

The -72G & gt;A nucleotide substitution impairs transcription of the ABO gene via reduction of promoter activity
Blood Transfus. 2023 Dec 21. doi: 10.2450/BloodTransfus.637. Online ahead of print.NO ABSTRACTPMID:38315538 | DOI:10.2450/BloodTransfus.637 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Hang Lei Jiewei Zheng Dong Xiang Hui Zhang Xuefeng Wang Xiaohong Cai Source Type: research

Inclusion of cryoprecipitate, pathogen-reduced, in the WHO model lists of essential medicines for adults and children: a call for action
Blood Transfus. 2024 Jan 31. doi: 10.2450/BloodTransfus.687. Online ahead of print.NO ABSTRACTPMID:38315539 | DOI:10.2450/BloodTransfus.687 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Jay S Epstein Yuyun Maryuningsih Jean-Claude Faber W Martin Smid Thierry Burnouf Source Type: research

First investigation of RH gene polymorphism in patients with sickle cell disease and associated blood donors in Cameroon, Central Africa
DISCUSSION: Beyond the comprehensive report of the nature and distribution of RH variant alleles in a subset of Cameroonian patients treated by transfusion therapy, this work highlights the need for an extensive review of current practice, including routine serologic typing procedures, preferably in the near future.PMID:38315540 | DOI:10.2450/BloodTransfus.660 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Jeanne Manga Messina Mbeti Caroline B énech Fran çoise Ngo Sack Estelle Wete Hortense Ngegni Pangetha Simon No ël Ateba Jules Tchatchueng Alexandre Njan Nloga Yann Fichou Source Type: research

Red blood cell transfusion in patients undergoing elective primary glioblastoma resection
This study aims to identify the clinical outcome of transfused glioblastoma patients undergoing primary surgical tumor resection and identify risk factors for RBC transfusion.MATERIAL AND METHODS: Between 2009 and 2019, 406 patients underwent elective primary glioblastoma resection. For multivariate analysis to assess risk factors for RBC transfusion, logistic regression was conducted. The impact of RBC transfusion on overall survival was assessed using Kaplan-Meier analysis.RESULTS: In total, 36 (8.9%) patients received RBC transfusion. Preoperative anemia rate was significantly higher in transfused patients compared to p...
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Vanessa Neef Sven K önig Hendrik Becker Daniel Dubinski Armin Flinspach Florian J Raimann Katharina Weber Michael W Ronellenfitsch Juergen Konczalla Elke Hattingen Marcus Czabanka Christian Senft Kai Zacharowski Peter Baumgarten Source Type: research

A systematic review of indications when and how a military walking Blood Bank could bridge blood product unavailability
DISCUSSION: This unusual protocol needs to be integrated into the medical support plan until conventional transfusion support can take over, and should include on-site blood collection from a donor, whether a WBB or an emergency donor panel. The benefits of such a protocol outweigh the risks in a life-threatening situation, especially since these risks can be anticipated and minimised by planning to pre-screen all potential donors before their deployment. Finally, educating and training the staff who must implement this unusual procedure can also improve the safety and survival rate of future patients.PMID:38315529 | DOI:1...
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Julie Degueldre Emilie Dessy France T'Sas V éronique Deneys Source Type: research

Anti-CD38 monoclonal antibody impairs CD34+ mobilization and affects clonogenic potential in multiple myeloma patients
DISCUSSION: Our findings underscore the impact of daratumumab-based treatment on CD34+ mobilization in a real-life, upfront plerixafor-free population of NDMM patients. Higher probability of requiring multiple apheresis occurred among daratumumab-treated patients. Interestingly, the observation that daratumumab might negatively impact BFU-E colony formation, independent of CD34+ cell count, offers novel biological perspectives. Appropriate strategies should be adopted by the Apheresis teams to mitigate these potential negative effects.PMID:38315530 | DOI:10.2450/BloodTransfus.667 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Arianna Zappaterra Ivan Civettini Anna Maria Cafro Laura Pezzetti Silvia Pierini Michela Anghilieri Laura Bellio Paola Bertazzoni Giovanni Grillo Periana Minga Maria L Pioltelli Emanuele Ravano Marianna Sassone Clara V Vigan ò Elisabetta B Volpato Carlo Source Type: research

Natural history of anti-PF4 antibodies in patients with vaccine-induced immune thrombocytopenia and thrombosis
Blood Transfus. 2024 Jan 29. doi: 10.2450/BloodTransfus.544. Online ahead of print.NO ABSTRACTPMID:38315531 | DOI:10.2450/BloodTransfus.544 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Elena Lotti Anna M Gori Martina Berteotti Angela Rogolino Francesca Cesari Daniela Poli Francesco Vannini Alessia Bertelli Betti Giusti Rossella Marcucci Source Type: research

Noninvasive fetal blood group antigen genotyping
Blood Transfus. 2024 Jan 29. doi: 10.2450/BloodTransfus.712. Online ahead of print.ABSTRACTNoninvasive fetal blood group antigen genotyping serves as a diagnostic tool to predict the risk of hemolytic disease of the fetus and newborn in pregnancies of immunized women. In addition, fetal RHD genotyping is used as an antenatal screening to guide targeted use of immunoglobulin prophylaxis in non-immunized RhD negative, pregnant women. Based on testing of cell-free DNA extracted from maternal plasma, these noninvasive assays demonstrate high performance accuracies. Consequently, noninvasive fetal blood group antigen genotyping...
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Frederik B Clausen C Ellen van der Schoot Source Type: research

The effects of pathogen reduction technology on apheresis platelet concentrates stored in PAS
DISCUSSION: The results of this study indicate that increased PSL induced by PRT treatment leads to a decreased in vitro platelet hemostatic efficacy and increased metabolic activity. However, the clinical impact of these alternations needs further investigation.PMID:38315533 | DOI:10.2450/BloodTransfus.600 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Stavros Tsalas Andreas G Tsantes Eleni Petrou Sofia Mellou Rozeta Sokou Electra Loukopoulou Anastasios G Kriebardis Sotirios P Fortis Dimitrios V Papadopoulos Aristeidis G Vaiopoulos Styliani Kokoris Argirios E Tsantes Source Type: research

Evaluation of an automated platelet aggregation method for detection of congenital or acquired platelet function defects
DISCUSSION: Thanks to this LTA technology, CS-2400, a routine coagulation analyzer widely available in routine laboratories, could prove useful for initial assessment of patients with a suspected PFD. Moreover, the PAL scores were a fairly accurate reflection of the platelet response to APT.PMID:38315534 | DOI:10.2450/BloodTransfus.601 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Anna Lecchi Marco Capecchi Lidia Padovan Andrea Artoni Nobuo Arai Sho Shinohara Silvia La Marca Flora Peyvandi Source Type: research

HLA class I expression on human platelets is highly variable and correlates with distinct allele group frequencies
DISCUSSION: Our data suggest an allele-dependent expression of HLA class I molecules on human platelets with distinct HLA allele group frequencies and different platelet subpopulation frequencies among blood donors.PMID:38315535 | DOI:10.2450/BloodTransfus.571 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Rocco Cantisani Valeria Del Re Francesca Toraldo Silvia Cantara Simone Pozzessere Giuseppe Marotta Adriano Spreafico Source Type: research

Establishment of a case registry that collaborates with a reference laboratory for blood group immunogenetics in Korea
Blood Transfus. 2023 Dec 19. doi: 10.2450/BloodTransfus.689. Online ahead of print.NO ABSTRACTPMID:38315536 | DOI:10.2450/BloodTransfus.689 (Source: Blood Transfusion)
Source: Blood Transfusion - February 5, 2024 Category: Hematology Authors: Dong Woo Shin Yun Ji Hong Kyoung Un Park Source Type: research