Interactions Between Genetic, Prenatal Substance Use, Puberty, and Parenting are Less Important for Understanding Adolescents' Internalizing, Externalizing, and Substance Use than Developmental Cascades in Multifactorial Models
This study tested interactions among puberty-related genetic risk, prenatal substance use, harsh discipline, and pubertal timing for the severity and directionality (i.e., differentiation) of externalizing and internalizing problems and adolescent substance use. This is a companion paper to Marceau et al. (2021) which examined the same influences in developmental cascade models. Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (n = 4504 White boys, n = 4287 White girls assessed from the prenatal period through 18.5 years). We hypothesized generally that later predictors would strengthen th...
Source: Behavior Genetics - October 15, 2023 Category: Genetics & Stem Cells Authors: Kristine Marceau Amy M Loviska Gregor Horvath Valerie S Knopik Source Type: research
Interactions Between Genetic, Prenatal Substance Use, Puberty, and Parenting are Less Important for Understanding Adolescents' Internalizing, Externalizing, and Substance Use than Developmental Cascades in Multifactorial Models
This study tested interactions among puberty-related genetic risk, prenatal substance use, harsh discipline, and pubertal timing for the severity and directionality (i.e., differentiation) of externalizing and internalizing problems and adolescent substance use. This is a companion paper to Marceau et al. (2021) which examined the same influences in developmental cascade models. Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (n = 4504 White boys, n = 4287 White girls assessed from the prenatal period through 18.5 years). We hypothesized generally that later predictors would strengthen th...
Source: Behavior Genetics - October 15, 2023 Category: Genetics & Stem Cells Authors: Kristine Marceau Amy M Loviska Gregor Horvath Valerie S Knopik Source Type: research
Interactions Between Genetic, Prenatal Substance Use, Puberty, and Parenting are Less Important for Understanding Adolescents' Internalizing, Externalizing, and Substance Use than Developmental Cascades in Multifactorial Models
This study tested interactions among puberty-related genetic risk, prenatal substance use, harsh discipline, and pubertal timing for the severity and directionality (i.e., differentiation) of externalizing and internalizing problems and adolescent substance use. This is a companion paper to Marceau et al. (2021) which examined the same influences in developmental cascade models. Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (n = 4504 White boys, n = 4287 White girls assessed from the prenatal period through 18.5 years). We hypothesized generally that later predictors would strengthen th...
Source: Behavior Genetics - October 15, 2023 Category: Genetics & Stem Cells Authors: Kristine Marceau Amy M Loviska Gregor Horvath Valerie S Knopik Source Type: research
Interactions Between Genetic, Prenatal Substance Use, Puberty, and Parenting are Less Important for Understanding Adolescents' Internalizing, Externalizing, and Substance Use than Developmental Cascades in Multifactorial Models
This study tested interactions among puberty-related genetic risk, prenatal substance use, harsh discipline, and pubertal timing for the severity and directionality (i.e., differentiation) of externalizing and internalizing problems and adolescent substance use. This is a companion paper to Marceau et al. (2021) which examined the same influences in developmental cascade models. Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (n = 4504 White boys, n = 4287 White girls assessed from the prenatal period through 18.5 years). We hypothesized generally that later predictors would strengthen th...
Source: Behavior Genetics - October 15, 2023 Category: Genetics & Stem Cells Authors: Kristine Marceau Amy M Loviska Gregor Horvath Valerie S Knopik Source Type: research
Interactions Between Genetic, Prenatal Substance Use, Puberty, and Parenting are Less Important for Understanding Adolescents' Internalizing, Externalizing, and Substance Use than Developmental Cascades in Multifactorial Models
This study tested interactions among puberty-related genetic risk, prenatal substance use, harsh discipline, and pubertal timing for the severity and directionality (i.e., differentiation) of externalizing and internalizing problems and adolescent substance use. This is a companion paper to Marceau et al. (2021) which examined the same influences in developmental cascade models. Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (n = 4504 White boys, n = 4287 White girls assessed from the prenatal period through 18.5 years). We hypothesized generally that later predictors would strengthen th...
Source: Behavior Genetics - October 15, 2023 Category: Genetics & Stem Cells Authors: Kristine Marceau Amy M Loviska Gregor Horvath Valerie S Knopik Source Type: research
Interactions Between Genetic, Prenatal Substance Use, Puberty, and Parenting are Less Important for Understanding Adolescents' Internalizing, Externalizing, and Substance Use than Developmental Cascades in Multifactorial Models
This study tested interactions among puberty-related genetic risk, prenatal substance use, harsh discipline, and pubertal timing for the severity and directionality (i.e., differentiation) of externalizing and internalizing problems and adolescent substance use. This is a companion paper to Marceau et al. (2021) which examined the same influences in developmental cascade models. Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (n = 4504 White boys, n = 4287 White girls assessed from the prenatal period through 18.5 years). We hypothesized generally that later predictors would strengthen th...
Source: Behavior Genetics - October 15, 2023 Category: Genetics & Stem Cells Authors: Kristine Marceau Amy M Loviska Gregor Horvath Valerie S Knopik Source Type: research
Interactions Between Genetic, Prenatal Substance Use, Puberty, and Parenting are Less Important for Understanding Adolescents' Internalizing, Externalizing, and Substance Use than Developmental Cascades in Multifactorial Models
This study tested interactions among puberty-related genetic risk, prenatal substance use, harsh discipline, and pubertal timing for the severity and directionality (i.e., differentiation) of externalizing and internalizing problems and adolescent substance use. This is a companion paper to Marceau et al. (2021) which examined the same influences in developmental cascade models. Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (n = 4504 White boys, n = 4287 White girls assessed from the prenatal period through 18.5 years). We hypothesized generally that later predictors would strengthen th...
Source: Behavior Genetics - October 15, 2023 Category: Genetics & Stem Cells Authors: Kristine Marceau Amy M Loviska Gregor Horvath Valerie S Knopik Source Type: research
Interactions Between Genetic, Prenatal Substance Use, Puberty, and Parenting are Less Important for Understanding Adolescents' Internalizing, Externalizing, and Substance Use than Developmental Cascades in Multifactorial Models
This study tested interactions among puberty-related genetic risk, prenatal substance use, harsh discipline, and pubertal timing for the severity and directionality (i.e., differentiation) of externalizing and internalizing problems and adolescent substance use. This is a companion paper to Marceau et al. (2021) which examined the same influences in developmental cascade models. Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (n = 4504 White boys, n = 4287 White girls assessed from the prenatal period through 18.5 years). We hypothesized generally that later predictors would strengthen th...
Source: Behavior Genetics - October 15, 2023 Category: Genetics & Stem Cells Authors: Kristine Marceau Amy M Loviska Gregor Horvath Valerie S Knopik Source Type: research
Interactions Between Genetic, Prenatal Substance Use, Puberty, and Parenting are Less Important for Understanding Adolescents' Internalizing, Externalizing, and Substance Use than Developmental Cascades in Multifactorial Models
This study tested interactions among puberty-related genetic risk, prenatal substance use, harsh discipline, and pubertal timing for the severity and directionality (i.e., differentiation) of externalizing and internalizing problems and adolescent substance use. This is a companion paper to Marceau et al. (2021) which examined the same influences in developmental cascade models. Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (n = 4504 White boys, n = 4287 White girls assessed from the prenatal period through 18.5 years). We hypothesized generally that later predictors would strengthen th...
Source: Behavior Genetics - October 15, 2023 Category: Genetics & Stem Cells Authors: Kristine Marceau Amy M Loviska Gregor Horvath Valerie S Knopik Source Type: research
Behavior Genetics Association 53rd Annual Meeting Abstracts
Behav Genet. 2023 Oct 12. doi: 10.1007/s10519-023-10156-9. Online ahead of print.NO ABSTRACTPMID:37828244 | DOI:10.1007/s10519-023-10156-9 (Source: Behavior Genetics)
Source: Behavior Genetics - October 12, 2023 Category: Genetics & Stem Cells Source Type: research
Behavior Genetics Association 53rd Annual Meeting Abstracts
Behav Genet. 2023 Oct 12. doi: 10.1007/s10519-023-10156-9. Online ahead of print.NO ABSTRACTPMID:37828244 | DOI:10.1007/s10519-023-10156-9 (Source: Behavior Genetics)
Source: Behavior Genetics - October 12, 2023 Category: Genetics & Stem Cells Source Type: research
Reviewers for Volume 53
Behav Genet. 2023 Oct 12. doi: 10.1007/s10519-023-10163-w. Online ahead of print.NO ABSTRACTPMID:37828243 | DOI:10.1007/s10519-023-10163-w (Source: Behavior Genetics)
Source: Behavior Genetics - October 12, 2023 Category: Genetics & Stem Cells Source Type: research
Behavior Genetics Association 53rd Annual Meeting Abstracts
Behav Genet. 2023 Oct 12. doi: 10.1007/s10519-023-10156-9. Online ahead of print.NO ABSTRACTPMID:37828244 | DOI:10.1007/s10519-023-10156-9 (Source: Behavior Genetics)
Source: Behavior Genetics - October 12, 2023 Category: Genetics & Stem Cells Source Type: research
Considerations, Caveats, and Suggestions for the Use of Polygenic Scores for Social and Behavioral Traits
Behav Genet. 2023 Oct 6. doi: 10.1007/s10519-023-10162-x. Online ahead of print.ABSTRACTPolygenic scores (PGS) are increasingly being used for prediction of social and behavioral traits, but suffer from many methodological, theoretical, and ethical concerns that profoundly limit their value. Primarily, these scores are derived from statistical correlations, carrying no inherent biological meaning, and thus may capture indirect effects. Further, the performance of these scores depends upon the diversity of the reference populations and the genomic panels from which they were derived, which consistently underrepresent minori...
Source: Behavior Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Amy L Non Jessica P Cerde ña Source Type: research
Considerations, Caveats, and Suggestions for the Use of Polygenic Scores for Social and Behavioral Traits
Behav Genet. 2023 Oct 6. doi: 10.1007/s10519-023-10162-x. Online ahead of print.ABSTRACTPolygenic scores (PGS) are increasingly being used for prediction of social and behavioral traits, but suffer from many methodological, theoretical, and ethical concerns that profoundly limit their value. Primarily, these scores are derived from statistical correlations, carrying no inherent biological meaning, and thus may capture indirect effects. Further, the performance of these scores depends upon the diversity of the reference populations and the genomic panels from which they were derived, which consistently underrepresent minori...
Source: Behavior Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Amy L Non Jessica P Cerde ña Source Type: research
