Exploring Relationships Between Internalizing Problems and Risky Sexual Behavior: A Twin Study
Behav Genet. 2023 May 11. doi: 10.1007/s10519-023-10146-x. Online ahead of print.ABSTRACTPrevious research links risky sexual behavior (RSB) to externalizing problems and to substance use, but little research has been conducted on relationships between internalizing problems (INT) and RSB. The current study addresses that literature gap, using both a twin sample from Colorado (N = 2567) and a second twin sample from Minnesota (N = 1131) in attempt to replicate initial results. We explored the hypothesis that the latent variable INT would be more strongly associated with the latent variable RSB for females than for males, e...
Source: Behavior Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Katie N Paulich Samantha M Freis Deepika R Dokuru Jordan D Alexander Scott I Vrieze Robin P Corley Matt McGue John K Hewitt Michael C Stallings Source Type: research
Exploring Relationships Between Internalizing Problems and Risky Sexual Behavior: A Twin Study
Behav Genet. 2023 May 11. doi: 10.1007/s10519-023-10146-x. Online ahead of print.ABSTRACTPrevious research links risky sexual behavior (RSB) to externalizing problems and to substance use, but little research has been conducted on relationships between internalizing problems (INT) and RSB. The current study addresses that literature gap, using both a twin sample from Colorado (N = 2567) and a second twin sample from Minnesota (N = 1131) in attempt to replicate initial results. We explored the hypothesis that the latent variable INT would be more strongly associated with the latent variable RSB for females than for males, e...
Source: Behavior Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Katie N Paulich Samantha M Freis Deepika R Dokuru Jordan D Alexander Scott I Vrieze Robin P Corley Matt McGue John K Hewitt Michael C Stallings Source Type: research
Genetic and Environmental Contributions to Subcortical Gray Matter Microstructure and Volume in the Developing Brain
Behav Genet. 2023 May;53(3):208-218. doi: 10.1007/s10519-023-10142-1. Epub 2023 Apr 26.ABSTRACTUsing baseline (ages 9-10) and two-year follow-up (ages 11-12) data from monozygotic and dizygotic twins enrolled in the longitudinal Adolescent Brain Cognitive DevelopmentSM Study, we investigated the genetic and environmental contributions to microstructure and volume of nine subcortical gray matter regions. Microstructure was assessed using diffusion MRI data analyzed using restriction spectrum imaging (RSI) and diffusion tensor imaging (DTI) models. The highest heritability estimates (estimate [95% confidence interval]) for m...
Source: Behavior Genetics - May 2, 2023 Category: Genetics & Stem Cells Authors: Richard Watts Lydia Rader Justin Grant Christopher G Filippi Source Type: research
Genetic and Environmental Contributions to Subcortical Gray Matter Microstructure and Volume in the Developing Brain
Behav Genet. 2023 May;53(3):208-218. doi: 10.1007/s10519-023-10142-1. Epub 2023 Apr 26.ABSTRACTUsing baseline (ages 9-10) and two-year follow-up (ages 11-12) data from monozygotic and dizygotic twins enrolled in the longitudinal Adolescent Brain Cognitive DevelopmentSM Study, we investigated the genetic and environmental contributions to microstructure and volume of nine subcortical gray matter regions. Microstructure was assessed using diffusion MRI data analyzed using restriction spectrum imaging (RSI) and diffusion tensor imaging (DTI) models. The highest heritability estimates (estimate [95% confidence interval]) for m...
Source: Behavior Genetics - May 2, 2023 Category: Genetics & Stem Cells Authors: Richard Watts Lydia Rader Justin Grant Christopher G Filippi Source Type: research
Genetic and Environmental Contributions to Subcortical Gray Matter Microstructure and Volume in the Developing Brain
Behav Genet. 2023 May;53(3):208-218. doi: 10.1007/s10519-023-10142-1. Epub 2023 Apr 26.ABSTRACTUsing baseline (ages 9-10) and two-year follow-up (ages 11-12) data from monozygotic and dizygotic twins enrolled in the longitudinal Adolescent Brain Cognitive DevelopmentSM Study, we investigated the genetic and environmental contributions to microstructure and volume of nine subcortical gray matter regions. Microstructure was assessed using diffusion MRI data analyzed using restriction spectrum imaging (RSI) and diffusion tensor imaging (DTI) models. The highest heritability estimates (estimate [95% confidence interval]) for m...
Source: Behavior Genetics - May 2, 2023 Category: Genetics & Stem Cells Authors: Richard Watts Lydia Rader Justin Grant Christopher G Filippi Source Type: research
Genetic and Environmental Contributions to Subcortical Gray Matter Microstructure and Volume in the Developing Brain
Behav Genet. 2023 May;53(3):208-218. doi: 10.1007/s10519-023-10142-1. Epub 2023 Apr 26.ABSTRACTUsing baseline (ages 9-10) and two-year follow-up (ages 11-12) data from monozygotic and dizygotic twins enrolled in the longitudinal Adolescent Brain Cognitive DevelopmentSM Study, we investigated the genetic and environmental contributions to microstructure and volume of nine subcortical gray matter regions. Microstructure was assessed using diffusion MRI data analyzed using restriction spectrum imaging (RSI) and diffusion tensor imaging (DTI) models. The highest heritability estimates (estimate [95% confidence interval]) for m...
Source: Behavior Genetics - May 2, 2023 Category: Genetics & Stem Cells Authors: Richard Watts Lydia Rader Justin Grant Christopher G Filippi Source Type: research
Genetic and Environmental Contributions to Subcortical Gray Matter Microstructure and Volume in the Developing Brain
Behav Genet. 2023 May;53(3):208-218. doi: 10.1007/s10519-023-10142-1. Epub 2023 Apr 26.ABSTRACTUsing baseline (ages 9-10) and two-year follow-up (ages 11-12) data from monozygotic and dizygotic twins enrolled in the longitudinal Adolescent Brain Cognitive DevelopmentSM Study, we investigated the genetic and environmental contributions to microstructure and volume of nine subcortical gray matter regions. Microstructure was assessed using diffusion MRI data analyzed using restriction spectrum imaging (RSI) and diffusion tensor imaging (DTI) models. The highest heritability estimates (estimate [95% confidence interval]) for m...
Source: Behavior Genetics - May 2, 2023 Category: Genetics & Stem Cells Authors: Richard Watts Lydia Rader Justin Grant Christopher G Filippi Source Type: research
Genetic and Environmental Contributions to Subcortical Gray Matter Microstructure and Volume in the Developing Brain
Behav Genet. 2023 May;53(3):208-218. doi: 10.1007/s10519-023-10142-1. Epub 2023 Apr 26.ABSTRACTUsing baseline (ages 9-10) and two-year follow-up (ages 11-12) data from monozygotic and dizygotic twins enrolled in the longitudinal Adolescent Brain Cognitive DevelopmentSM Study, we investigated the genetic and environmental contributions to microstructure and volume of nine subcortical gray matter regions. Microstructure was assessed using diffusion MRI data analyzed using restriction spectrum imaging (RSI) and diffusion tensor imaging (DTI) models. The highest heritability estimates (estimate [95% confidence interval]) for m...
Source: Behavior Genetics - May 2, 2023 Category: Genetics & Stem Cells Authors: Richard Watts Lydia Rader Justin Grant Christopher G Filippi Source Type: research
Genetic and Environmental Contributions to Subcortical Gray Matter Microstructure and Volume in the Developing Brain
Behav Genet. 2023 May;53(3):208-218. doi: 10.1007/s10519-023-10142-1. Epub 2023 Apr 26.ABSTRACTUsing baseline (ages 9-10) and two-year follow-up (ages 11-12) data from monozygotic and dizygotic twins enrolled in the longitudinal Adolescent Brain Cognitive DevelopmentSM Study, we investigated the genetic and environmental contributions to microstructure and volume of nine subcortical gray matter regions. Microstructure was assessed using diffusion MRI data analyzed using restriction spectrum imaging (RSI) and diffusion tensor imaging (DTI) models. The highest heritability estimates (estimate [95% confidence interval]) for m...
Source: Behavior Genetics - May 2, 2023 Category: Genetics & Stem Cells Authors: Richard Watts Lydia Rader Justin Grant Christopher G Filippi Source Type: research
ABCD Behavior Genetics: Twin, Family, and Genomic Studies Using the Adolescent Brain Cognitive Development (ABCD) Study Dataset
Behav Genet. 2023 Apr 25. doi: 10.1007/s10519-023-10144-z. Online ahead of print.NO ABSTRACTPMID:37095243 | DOI:10.1007/s10519-023-10144-z (Source: Behavior Genetics)
Source: Behavior Genetics - April 25, 2023 Category: Genetics & Stem Cells Authors: Sylia Wilson Chun Chieh Fan John Hewitt Source Type: research
Genotype Data and Derived Genetic Instruments of Adolescent Brain Cognitive Development Study < sup > ® < /sup > for Better Understanding of Human Brain Development
Behav Genet. 2023 Apr 24. doi: 10.1007/s10519-023-10143-0. Online ahead of print.ABSTRACTThe data release of Adolescent Brain Cognitive Development® (ABCD) Study represents an extensive resource for investigating factors relating to child development and mental wellbeing. The genotype data of ABCD has been used extensively in the context of genetic analysis, including genome-wide association studies and polygenic score predictions. However, there are unique opportunities provided by ABCD genetic data that have not yet been fully tapped. The diverse genomic variability, the enriched relatedness among ABCD subsets, and the ...
Source: Behavior Genetics - April 24, 2023 Category: Genetics & Stem Cells Authors: Chun Chieh Fan Robert Loughnan Sylia Wilson John K Hewitt ABCD Genetic Working Group Source Type: research
A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study
Behav Genet. 2023 Apr 18. doi: 10.1007/s10519-023-10140-3. Online ahead of print.ABSTRACTGenetic risk for Late Onset Alzheimer Disease (AD) has been associated with lower cognition and smaller hippocampal volume in healthy young adults. However, whether these and other associations are present during childhood remains unclear. Using data from 5556 genomically-confirmed European ancestry youth who completed the baseline session of the ongoing the Adolescent Brain Cognitive DevelopmentSM Study (ABCD Study®), our phenome-wide association study estimating associations between four indices of genetic risk for late-onset AD (i....
Source: Behavior Genetics - April 18, 2023 Category: Genetics & Stem Cells Authors: Aaron J Gorelik Sarah E Paul Nicole R Karcher Emma C Johnson Isha Nagella Lauren Blaydon Hailey Modi Isabella S Hansen Sarah M C Colbert David A A Baranger Sara A Norton Isaiah Spears Brian Gordon Wei Zhang Patrick L Hill Thomas F Oltmanns Janine D Bijste Source Type: research
A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study
Behav Genet. 2023 Apr 18. doi: 10.1007/s10519-023-10140-3. Online ahead of print.ABSTRACTGenetic risk for Late Onset Alzheimer Disease (AD) has been associated with lower cognition and smaller hippocampal volume in healthy young adults. However, whether these and other associations are present during childhood remains unclear. Using data from 5556 genomically-confirmed European ancestry youth who completed the baseline session of the ongoing the Adolescent Brain Cognitive DevelopmentSM Study (ABCD Study®), our phenome-wide association study estimating associations between four indices of genetic risk for late-onset AD (i....
Source: Behavior Genetics - April 18, 2023 Category: Genetics & Stem Cells Authors: Aaron J Gorelik Sarah E Paul Nicole R Karcher Emma C Johnson Isha Nagella Lauren Blaydon Hailey Modi Isabella S Hansen Sarah M C Colbert David A A Baranger Sara A Norton Isaiah Spears Brian Gordon Wei Zhang Patrick L Hill Thomas F Oltmanns Janine D Bijste Source Type: research
A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study
Behav Genet. 2023 Apr 18. doi: 10.1007/s10519-023-10140-3. Online ahead of print.ABSTRACTGenetic risk for Late Onset Alzheimer Disease (AD) has been associated with lower cognition and smaller hippocampal volume in healthy young adults. However, whether these and other associations are present during childhood remains unclear. Using data from 5556 genomically-confirmed European ancestry youth who completed the baseline session of the ongoing the Adolescent Brain Cognitive DevelopmentSM Study (ABCD Study®), our phenome-wide association study estimating associations between four indices of genetic risk for late-onset AD (i....
Source: Behavior Genetics - April 18, 2023 Category: Genetics & Stem Cells Authors: Aaron J Gorelik Sarah E Paul Nicole R Karcher Emma C Johnson Isha Nagella Lauren Blaydon Hailey Modi Isabella S Hansen Sarah M C Colbert David A A Baranger Sara A Norton Isaiah Spears Brian Gordon Wei Zhang Patrick L Hill Thomas F Oltmanns Janine D Bijste Source Type: research
A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study
Behav Genet. 2023 Apr 18. doi: 10.1007/s10519-023-10140-3. Online ahead of print.ABSTRACTGenetic risk for Late Onset Alzheimer Disease (AD) has been associated with lower cognition and smaller hippocampal volume in healthy young adults. However, whether these and other associations are present during childhood remains unclear. Using data from 5556 genomically-confirmed European ancestry youth who completed the baseline session of the ongoing the Adolescent Brain Cognitive DevelopmentSM Study (ABCD Study®), our phenome-wide association study estimating associations between four indices of genetic risk for late-onset AD (i....
Source: Behavior Genetics - April 18, 2023 Category: Genetics & Stem Cells Authors: Aaron J Gorelik Sarah E Paul Nicole R Karcher Emma C Johnson Isha Nagella Lauren Blaydon Hailey Modi Isabella S Hansen Sarah M C Colbert David A A Baranger Sara A Norton Isaiah Spears Brian Gordon Wei Zhang Patrick L Hill Thomas F Oltmanns Janine D Bijste Source Type: research
