Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
Behav Genet. 2024 Feb 14. doi: 10.1007/s10519-023-10174-7. Online ahead of print.ABSTRACTThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psy...
Source: Behavior Genetics - February 14, 2024 Category: Genetics & Stem Cells Authors: Susanne Bruins Elsje van Bergen Maurits W Masselink Stefania A Barzeva Catharina A Hartman Roy Otten Nanda N J Rommelse Conor V Dolan Dorret I Boomsma Source Type: research
A Genetically Informed Study of the Association Between Perceived Stress and Loneliness
Behav Genet. 2024 Feb 11. doi: 10.1007/s10519-023-10176-5. Online ahead of print.ABSTRACTAlthough research shows a strong positive association between perceived stress and loneliness, the genetic and environmental etiology underlying their association remains unknown. People with a genetic predisposition to perceived stress, for example, may be more prone to feeling lonely and vice versa. Conversely, unique factors in people's lives may explain differences in perceived stress levels that, in turn, affect feelings of loneliness. We tested whether genetic factors, environmental factors, or both account for the association be...
Source: Behavior Genetics - February 11, 2024 Category: Genetics & Stem Cells Authors: Ryan Moshtael Morgan E Lynch Glen E Duncan Christopher R Beam Source Type: research
Statistical and Machine Learning Analysis in Brain-Imaging Genetics: A Review of Methods
Behav Genet. 2024 Feb 10. doi: 10.1007/s10519-024-10177-y. Online ahead of print.ABSTRACTBrain-imaging-genetic analysis is an emerging field of research that aims at aggregating data from neuroimaging modalities, which characterize brain structure or function, and genetic data, which capture the structure and function of the genome, to explain or predict normal (or abnormal) brain performance. Brain-imaging-genetic studies offer great potential for understanding complex brain-related diseases/disorders of genetic etiology. Still, a combined brain-wide genome-wide analysis is difficult to perform as typical datasets fuse mu...
Source: Behavior Genetics - February 9, 2024 Category: Genetics & Stem Cells Authors: Connor L Cheek Peggy Lindner Elena L Grigorenko Source Type: research
Genotype-Environment Interaction in ADHD: Genetic Predisposition Determines the Extent to Which Environmental Influences Explain Variability in the Symptom Dimensions Hyperactivity and Inattention
This study investigated whether a genetic predisposition [Note that the term 'genetic predisposition' was used in this manuscript to refer to an estimate based on twin modeling (an individual's score on the latent trait that resembles additive genetic influences) in the particular population being examined.] for the symptom dimensions hyperactivity and inattention determines the extent to which unique-environmental influences explain variability in these symptoms. To this purpose, we analysed a sample drawn from the Twins Early Development Study (TEDS) that consisted of item-level scores of 2168 16-year-old twin pairs who ...
Source: Behavior Genetics - January 25, 2024 Category: Genetics & Stem Cells Authors: Inga Schwabe Miljan Jovi ć Kaili Rimfeld Andrea G Allegrini St éphanie M van den Berg Source Type: research
Advancing Diversity in Behavior Genetics: Strategies for Incorporating Undergraduates into Student-Driven Research
Behav Genet. 2024 Jan;54(1):4-23. doi: 10.1007/s10519-023-10172-9. Epub 2024 Jan 22.ABSTRACTUndergraduate research experiences are crucial for fostering the next generation of behavior genetics researchers. However, incorporating undergraduates into research can be challenging for faculty mentors. In this article, we provide strategies for successfully integrating undergraduates into behavior genetics research based on our experiences mentoring undergraduates in our lab. These strategies include: (1) Practicing reflexivity, specifically an ongoing self-examination and critical self-awareness of personal biases, beliefs, an...
Source: Behavior Genetics - January 22, 2024 Category: Genetics & Stem Cells Authors: S Mason Garrison Emma E Webster Rachel Good Source Type: research
Key Grazing Behaviours of Beef Cattle Identify Specific Genotypes of the Glutamate Metabotropic Receptor 5 Gene (GRM5)
Behav Genet. 2024 Mar;54(2):212-229. doi: 10.1007/s10519-023-10169-4. Epub 2024 Jan 16.ABSTRACTGenotype-phenotype associations between the bovine genome and grazing behaviours measured over time and across contexts have been reported in the past decade, with these suggesting the potential for genetic control over grazing personalities in beef cattle. From the large array of metrics used to describe grazing personality behaviours (GP-behaviours), it is still unclear which ones are linked to specific genes. Our prior observational study has reported associations and trends towards associations between genotypes of the glutam...
Source: Behavior Genetics - January 15, 2024 Category: Genetics & Stem Cells Authors: Cristian Anibal Moreno Garc ía Susana Beatr íz Perelman Robyn Dynes Thomas M R Maxwell Huitong Zhou Jonathan Hickford Source Type: research
