Developing a diagnostic model for predicting prostate cancer: a retrospective study based on Chinese multicenter clinical data
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202342. Online ahead of print.ABSTRACTThe overdiagnosis of prostate cancer (PCa) caused by nonspecific elevation serum prostate-specific antigen (PSA) and the overtreatment of indolent PCa have become a global problem that needs to be solved urgently. We aimed to construct a prediction model and provide a risk stratification system to reduce unnecessary biopsies. In this retrospective study, clinical data of 1807 patients from three Chinese hospitals were used. The final model was built using stepwise logistic regression analysis. The apparent performance of the model was assess...
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Chang-Ming Wang Lei Yuan Xue-Han Liu Shu-Qiu Chen Hai-Feng Wang Qi-Fei Dong Bin Zhang Ming-Shuo Huang Zhi-Yong Zhang Jun Xiao Tao Tao Source Type: research
Corrigendum to "MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients"
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202348. Online ahead of print.NO ABSTRACTPMID:37750804 | DOI:10.4103/aja202348 (Source: Asian Journal of Andrology)
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Jun-Hao Zhou Qi-Zhao Zhou Jian-Kun Yang Xiao-Ming Lyu Jun Bian Wen-Bin Guo Zi-Jian Chen Ming Xia Hui Xia Tao Qi Xin Li Cun-Dong Liu Source Type: research
Developing a diagnostic model for predicting prostate cancer: a retrospective study based on Chinese multicenter clinical data
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202342. Online ahead of print.ABSTRACTThe overdiagnosis of prostate cancer (PCa) caused by nonspecific elevation serum prostate-specific antigen (PSA) and the overtreatment of indolent PCa have become a global problem that needs to be solved urgently. We aimed to construct a prediction model and provide a risk stratification system to reduce unnecessary biopsies. In this retrospective study, clinical data of 1807 patients from three Chinese hospitals were used. The final model was built using stepwise logistic regression analysis. The apparent performance of the model was assess...
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Chang-Ming Wang Lei Yuan Xue-Han Liu Shu-Qiu Chen Hai-Feng Wang Qi-Fei Dong Bin Zhang Ming-Shuo Huang Zhi-Yong Zhang Jun Xiao Tao Tao Source Type: research
Corrigendum to "MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients"
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202348. Online ahead of print.NO ABSTRACTPMID:37750804 | DOI:10.4103/aja202348 (Source: Asian Journal of Andrology)
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Jun-Hao Zhou Qi-Zhao Zhou Jian-Kun Yang Xiao-Ming Lyu Jun Bian Wen-Bin Guo Zi-Jian Chen Ming Xia Hui Xia Tao Qi Xin Li Cun-Dong Liu Source Type: research
Developing a diagnostic model for predicting prostate cancer: a retrospective study based on Chinese multicenter clinical data
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202342. Online ahead of print.ABSTRACTThe overdiagnosis of prostate cancer (PCa) caused by nonspecific elevation serum prostate-specific antigen (PSA) and the overtreatment of indolent PCa have become a global problem that needs to be solved urgently. We aimed to construct a prediction model and provide a risk stratification system to reduce unnecessary biopsies. In this retrospective study, clinical data of 1807 patients from three Chinese hospitals were used. The final model was built using stepwise logistic regression analysis. The apparent performance of the model was assess...
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Chang-Ming Wang Lei Yuan Xue-Han Liu Shu-Qiu Chen Hai-Feng Wang Qi-Fei Dong Bin Zhang Ming-Shuo Huang Zhi-Yong Zhang Jun Xiao Tao Tao Source Type: research
Corrigendum to "MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients"
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202348. Online ahead of print.NO ABSTRACTPMID:37750804 | DOI:10.4103/aja202348 (Source: Asian Journal of Andrology)
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Jun-Hao Zhou Qi-Zhao Zhou Jian-Kun Yang Xiao-Ming Lyu Jun Bian Wen-Bin Guo Zi-Jian Chen Ming Xia Hui Xia Tao Qi Xin Li Cun-Dong Liu Source Type: research
Developing a diagnostic model for predicting prostate cancer: a retrospective study based on Chinese multicenter clinical data
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202342. Online ahead of print.ABSTRACTThe overdiagnosis of prostate cancer (PCa) caused by nonspecific elevation serum prostate-specific antigen (PSA) and the overtreatment of indolent PCa have become a global problem that needs to be solved urgently. We aimed to construct a prediction model and provide a risk stratification system to reduce unnecessary biopsies. In this retrospective study, clinical data of 1807 patients from three Chinese hospitals were used. The final model was built using stepwise logistic regression analysis. The apparent performance of the model was assess...
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Chang-Ming Wang Lei Yuan Xue-Han Liu Shu-Qiu Chen Hai-Feng Wang Qi-Fei Dong Bin Zhang Ming-Shuo Huang Zhi-Yong Zhang Jun Xiao Tao Tao Source Type: research
Corrigendum to "MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients"
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202348. Online ahead of print.NO ABSTRACTPMID:37750804 | DOI:10.4103/aja202348 (Source: Asian Journal of Andrology)
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Jun-Hao Zhou Qi-Zhao Zhou Jian-Kun Yang Xiao-Ming Lyu Jun Bian Wen-Bin Guo Zi-Jian Chen Ming Xia Hui Xia Tao Qi Xin Li Cun-Dong Liu Source Type: research
Developing a diagnostic model for predicting prostate cancer: a retrospective study based on Chinese multicenter clinical data
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202342. Online ahead of print.ABSTRACTThe overdiagnosis of prostate cancer (PCa) caused by nonspecific elevation serum prostate-specific antigen (PSA) and the overtreatment of indolent PCa have become a global problem that needs to be solved urgently. We aimed to construct a prediction model and provide a risk stratification system to reduce unnecessary biopsies. In this retrospective study, clinical data of 1807 patients from three Chinese hospitals were used. The final model was built using stepwise logistic regression analysis. The apparent performance of the model was assess...
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Chang-Ming Wang Lei Yuan Xue-Han Liu Shu-Qiu Chen Hai-Feng Wang Qi-Fei Dong Bin Zhang Ming-Shuo Huang Zhi-Yong Zhang Jun Xiao Tao Tao Source Type: research
Corrigendum to "MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients"
Asian J Androl. 2023 Sep 22. doi: 10.4103/aja202348. Online ahead of print.NO ABSTRACTPMID:37750804 | DOI:10.4103/aja202348 (Source: Asian Journal of Andrology)
Source: Asian Journal of Andrology - September 26, 2023 Category: Urology & Nephrology Authors: Jun-Hao Zhou Qi-Zhao Zhou Jian-Kun Yang Xiao-Ming Lyu Jun Bian Wen-Bin Guo Zi-Jian Chen Ming Xia Hui Xia Tao Qi Xin Li Cun-Dong Liu Source Type: research
Detection and evaluation of different morphological forms of Mycoplasma hominis in human semen
Asian J Androl. 2023 Sep 15. doi: 10.4103/aja202333. Online ahead of print.ABSTRACTRecently discovered microcolonial forms of Mycoplasma hominis (M. hominis) and their impact on human spermatogenesis are studied. The spermatozoa of 125 fertile men (sperm donors; from Reprobank [Reproductive Tissue Bank, Moscow, Russia]) and of 93 patients with fertility problems (from the Federal State Budgetary Institution "Research Centre for Medical Genetics [RCMG]", Moscow, Russia) were used. Classical colonies of M. hominis and microcolonies were detected by molecular biological methods, culture of bacteria, and transmission electron ...
Source: Asian Journal of Andrology - September 22, 2023 Category: Urology & Nephrology Authors: Elizaveta Bragina Tatyana Sorokina Avtandil Chogovadze Yulia Shevchenko Vyacheslav Chernykh Olga Barkhatova Irina Rakovskaya Source Type: research
Association between MTHFR c.677C & gt;T variant and erectile dysfunction among males attending fertility clinic
In this study, we recruited 1254 participants who underwent ED assessed by the International Index of Erectile Function-5. The MTHFR c.677C>T variant was also measured by fluorescence polymerase chain reaction (PCR). No significant difference in the genotypic frequency of the MTHFR C677T polymorphism (CC, CT, and TT) was observed between men from the ED and non-ED groups. In addition, on binary logistic regression analysis, both crude and adjusted models showed that the risk of ED was not significantly associated with the C677T polymorphism. Interestingly, a significantly higher frequency of the 677TT polymorphism was f...
Source: Asian Journal of Andrology - September 22, 2023 Category: Urology & Nephrology Authors: Shun Bai Ming-Zhen Li Yang-Yang Wan Xue-Chun Hu Yi-Xun Liu Xian-Hong Tong Tong-Hang Guo Lu Zong Ran Liu Yuan-Qi Zhao Ping Xiang Bo Xu Xiao-Hua Jiang Source Type: research
Pharmacotherapy of urethral stricture
Asian J Androl. 2023 Sep 15. doi: 10.4103/aja202341. Online ahead of print.ABSTRACTUrethral stricture is characterized by the chronic formation of fibrous tissue, leading to the narrowing of the urethral lumen. Despite the availability of various endoscopic treatments, the recurrence of urethral strictures remains a common challenge. Postsurgery pharmacotherapy targeting tissue fibrosis is a promising option for reducing recurrence rates. Although drugs cannot replace surgery, they can be used as adjuvant therapies to improve outcomes. In this regard, many drugs have been proposed based on the mechanisms underlying the pat...
Source: Asian Journal of Andrology - September 22, 2023 Category: Urology & Nephrology Authors: Hui Luo Ke-Cheng Lou Ling-Yu Xie Fei Zeng Jun-Rong Zou Source Type: research
Detection and evaluation of different morphological forms of Mycoplasma hominis in human semen
Asian J Androl. 2023 Sep 15. doi: 10.4103/aja202333. Online ahead of print.ABSTRACTRecently discovered microcolonial forms of Mycoplasma hominis (M. hominis) and their impact on human spermatogenesis are studied. The spermatozoa of 125 fertile men (sperm donors; from Reprobank [Reproductive Tissue Bank, Moscow, Russia]) and of 93 patients with fertility problems (from the Federal State Budgetary Institution "Research Centre for Medical Genetics [RCMG]", Moscow, Russia) were used. Classical colonies of M. hominis and microcolonies were detected by molecular biological methods, culture of bacteria, and transmission electron ...
Source: Asian Journal of Andrology - September 22, 2023 Category: Urology & Nephrology Authors: Elizaveta Bragina Tatyana Sorokina Avtandil Chogovadze Yulia Shevchenko Vyacheslav Chernykh Olga Barkhatova Irina Rakovskaya Source Type: research
Association between MTHFR c.677C & gt;T variant and erectile dysfunction among males attending fertility clinic
In this study, we recruited 1254 participants who underwent ED assessed by the International Index of Erectile Function-5. The MTHFR c.677C>T variant was also measured by fluorescence polymerase chain reaction (PCR). No significant difference in the genotypic frequency of the MTHFR C677T polymorphism (CC, CT, and TT) was observed between men from the ED and non-ED groups. In addition, on binary logistic regression analysis, both crude and adjusted models showed that the risk of ED was not significantly associated with the C677T polymorphism. Interestingly, a significantly higher frequency of the 677TT polymorphism was f...
Source: Asian Journal of Andrology - September 22, 2023 Category: Urology & Nephrology Authors: Shun Bai Ming-Zhen Li Yang-Yang Wan Xue-Chun Hu Yi-Xun Liu Xian-Hong Tong Tong-Hang Guo Lu Zong Ran Liu Yuan-Qi Zhao Ping Xiang Bo Xu Xiao-Hua Jiang Source Type: research
