Recommendations of the Experts of the Polish Cardiac Society (PCS) and the Polish Lipid Association (PoLA) on the diagnosis and management of elevated lipoprotein(a) levels
Arch Med Sci. 2024 Jan 31;20(1):8-27. doi: 10.5114/aoms/183522. eCollection 2024.ABSTRACTLipoprotein(a) [Lp(a)] is made up of a low-density lipoprotein (LDL) particle and a specific apolipoprotein(a). The blood concentration of Lp(a) is approximately 90% genetically determined, and the main genetic factor determining Lp(a) levels is the size of the apo(a) isoform, which is determined by the number of KIV2 domain repeats. The size of the apo(a) isoform is inversely proportional to the blood concentration of Lp(a). Lp(a) is a strong and independent cardiovascular risk factor. Elevated Lp(a) levels ≥ 50 mg/dl (≥ 125 nmol/...
Source: Archives of Medical Science - February 28, 2024 Category: Biomedical Science Authors: Bo żena Sosnowska Janina Stepinska Przemyslaw Mitkowski Agata Bielecka-Dabrowa Beata Bobrowska Jan Budzianowski Pawel Burchardt Krzysztof Chlebus Piotr Dobrowolski Mariusz Gasior Piotr Jankowski Jacek Kubica Agnieszka Mickiewicz Malgorzata Mysliwiec Tade Source Type: research

The Polish Experts' Consensus Statement: 2023 update on new therapies for migraine
Arch Med Sci. 2024 Jan 12;20(1):339-343. doi: 10.5114/aoms/175063. eCollection 2024.NO ABSTRACTPMID:38414481 | PMC:PMC10895940 | DOI:10.5114/aoms/175063 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: Biomedical Science Authors: Izabela Domitrz Wojciech Kozubski Magdalena Boczarska Adam St ępień Jacek J Ro żniecki Source Type: research

Cuproptosis-related genes are involved in immunodeficiency following ischemic stroke
CONCLUSIONS: Our findings revealed cuproptosis-related hub genes, which could provide useful biomarkers in ischemic stroke.PMID:38414482 | PMC:PMC10895967 | DOI:10.5114/aoms/182909 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: Biomedical Science Authors: Li Jinshi Yu Cong Shu Liang Ren Dabin Zheng Ping Source Type: research

Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy
CONCLUSIONS: Lysozyme promotes kidney fibrosis via the JAK/STAT3 signaling pathway in diabetic nephropathy, and glucose may promote fibroblast proliferation by promoting LYZ auto-secretion.PMID:38414445 | PMC:PMC10895955 | DOI:10.5114/aoms/170160 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Yan Ren Mengjie Yu Danna Zheng Wenfang He Juan Jin Source Type: research

Level of basic hope and symptoms of anxiety and depression in women after miscarriage
CONCLUSIONS: It was found that the level of hope significantly increased after 3 months compared to this level during hospitalization. Hope was associated with lower levels of anxiety and depression symptoms.PMID:38414446 | PMC:PMC10895938 | DOI:10.5114/aoms/175504 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Katarzyna Bia łek Marcin Sadowski Olga Adamczyk-Gruszka Jakub M łodawski Grzegorz Świercz Source Type: research