lncRNA GAPLINC regulates vascular endothelial cell apoptosis in atherosclerosis
CONCLUSIONS: The present study demonstrates that upregulation of lncRNA GAPLINC represses the binding of miR-183-5p to the PDCD4 promoter region and then promotes PDCD4 expression, thereby inducing cell apoptosis and suppressing endothelial cell proliferation.PMID:38414459 | PMC:PMC10895973 | DOI:10.5114/aoms/169383 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Jun Pan Bing Wang Xibin Pu Chenyang Qiu Donglin Li Ziheng Wu Honkun Zhang Yangyan He Source Type: research
Atypical presentation of Lyme disease
Arch Med Sci. 2024 Jan 18;20(1):344-347. doi: 10.5114/aoms/175494. eCollection 2024.NO ABSTRACTPMID:38414461 | PMC:PMC10895935 | DOI:10.5114/aoms/175494 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Agnieszka Jarosi ńska Aleksandra Pil śniak Aleksandra Cie śla-Fuławka Wioletta Dziubak Joanna Siuda Micha ł Tadeusz Holecki Source Type: research
Efficacy of ornidazole for pericoronitis: a meta-analysis and systematic review
CONCLUSIONS: Ornidazole is effective in the treatment of pericoronitis, with more advantages. Still, the effects and safety of ornidazole in the treatment of pericoronitis need to be evaluated by more high-quality RCTs with larger sample sizes.PMID:38414462 | PMC:PMC10895945 | DOI:10.5114/aoms/171907 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Ruobing Du Kai Ba Yaxin Yang Yueyue Zhao Yupeng Lin Source Type: research
Interleukins: pathophysiological role in acute pancreatitis
Arch Med Sci. 2024 Jan 31;20(1):138-156. doi: 10.5114/aoms/178183. eCollection 2024.ABSTRACTAcute pancreatitis (AP) is a common inflammatory state characterized by a clinical course that can lead to serious local and extrapancreatic organ malfunction and failure. Interleukins (ILs) are biologically active glycoproteins primarily produced by macrophages and lymphocytes. According to the literature, there are many ILs. However, this article represents a summary of the role of ILs in AP, such as IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12, IL-13, IL-14, IL-15, IL-16, IL-17, IL-18, IL-19, and IL-2...
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Saira Rafaqat Dimitrios Patoulias Amir Hossein Behnoush Saima Sharif Aleksandra Klisic Source Type: research
Cystatins: unravelling the biological implications for neuroprotection
This article focuses on the potential use of cystatins, with special emphasis on easily obtained ovocystatin, in the treatment of neurodegenerative diseases, such as dementia. The current evidence on cystatin use has shed light on its mechanisms of action and therapeutic implications for neuroprotection and maintenance of cognitive functions.PMID:38414464 | PMC:PMC10895963 | DOI:10.5114/aoms/171706 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Bart łomiej Stańczykiewicz Mateusz Łuc Maciej Banach Agnieszka Zab łocka Source Type: research
The Cardiac-Kidney-Liver (CKL) syndrome: the "real entity" of type 2 diabetes mellitus
Arch Med Sci. 2024 Jan 31;20(1):207-215. doi: 10.5114/aoms/183070. eCollection 2024.NO ABSTRACTPMID:38414467 | PMC:PMC10895975 | DOI:10.5114/aoms/183070 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Niki Katsiki Genovefa Kolovou Andreas Melidonis Maciej Banach Source Type: research
Evaluation of selected factors influencing sleep disorders in paramedics during the COVID-19 pandemic
CONCLUSIONS: The main factors influencing the development of sleep disorders were female gender, use of sleep aids and not having a life partner. In contrast, older age and longer job tenure, being married, and having good relationships with family members had a protective effect.PMID:38414468 | PMC:PMC10895942 | DOI:10.5114/aoms/169909 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Kamil Piotr Marczewski Magdalena Piegza Natalia Justyna Gospodarczyk Alicja Zofia Gospodarczyk Mateusz Marcinek Micha ł Tkocz Krystyn Sosada Source Type: research
A simple program to improve the appropriateness of red blood cell transfusions in non-bleeding hospital patients: a before-and-after study
CONCLUSIONS: A simple program may lead to a 3-fold decrease in transfusion rate and a significant increase in the percentage of appropriate RBC transfusions.PMID:38414470 | PMC:PMC10895966 | DOI:10.5114/aoms/177281 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Jan Herzyk Dawid Wilczek Renata Kopczy ńska Piotr F Czempik Source Type: research
Parents' attitudes towards children's transplantology
CONCLUSIONS: There is a need for social education in the field of pediatric transplantation and to facilitate access to professional psychological care for pediatric patients and/or their caregivers.PMID:38414471 | PMC:PMC10895933 | DOI:10.5114/aoms/178277 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Olga Paulina Sawicka Anita Helena Koci ęba-Łaciak Dominik Ga łuszka Katarzyna Ślusarczyk Jakub Kasperowicz Source Type: research
Obesity and lung cancer - is programmed death ligand-1 (PD-1L) expression a connection?
CONCLUSIONS: Apart from the above, the authors did not find any statistically significant correlation between PD-1L expression on lung cancer cells and body mass index, either in the whole group or in histological subgroups.PMID:38414472 | PMC:PMC10895970 | DOI:10.5114/aoms/175470 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Jakub Krzysztof Ga łązka Marcin Czeczelewski Tomasz Kucharczyk Katarzyna Szklener S ławomir Mańdziuk Source Type: research
Systemic concentrations of IL-18, TFG- β, RANTES, ICAM-1 and uPAR as combined pathway-related factors may help in identification of patients suffering from depressive disorder
Arch Med Sci. 2024 Jan 31;20(1):348-353. doi: 10.5114/aoms/178276. eCollection 2024.NO ABSTRACTPMID:38414473 | PMC:PMC10895941 | DOI:10.5114/aoms/178276 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: El żbieta Małujlo-Balcerska Tadeusz Pietras Source Type: research
The impact of a Telehealth-based Behavioral Lifestyle Program on hypertension control in African American participants: results from the HEALS Med-Tech randomized controlled trial
CONCLUSIONS: HEALS Med-Tech demonstrates potential in HTN management for AAs, advocating for culturally tailored, tech-integrated healthcare expansion.PMID:38414475 | PMC:PMC10895937 | DOI:10.5114/aoms/177686 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Sunita Dodani Amanda Clarke Ismail El Moudden Tharidu Gunawardena Navdhit Bedi Source Type: research
Trends of ischemic heart disease mortality attributable to smoking in the five countries with the highest number of smokers during 1990-2019: an age-period-cohort analysis
CONCLUSIONS: From 1990 to 2019, mortality from IHD caused by smoking showed a downward trend in these five countries. However, the pattern of increased mortality from IHD in women caused by smoking warrants further study.PMID:38414476 | PMC:PMC10895949 | DOI:10.5114/aoms/182886 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Shaoliang Tang Juan Meng Xinghua Zhao Wenting Sun Source Type: research
Association of leptin receptor gene Gln223Arg polymorphism with insulin resistance and hyperglycemia in patients with metabolic syndrome
CONCLUSIONS: Gln223Arg polymorphism of the leptin receptor gene may be a marker of predisposition to insulin resistance in the Kyrgyz population. Further studies are necessary to confirm these results in populations from other regions.PMID:38414477 | PMC:PMC10895948 | DOI:10.5114/aoms/170121 (Source: Archives of Medical Science)
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Erkin Mirrakhimov Erkaiym Bektasheva Jainagul Isakova Olga Lunegova Alina Kerimkulova Saamay Abilova Ksenya Neronova Nazira Alibaeva Yrysbek U Mamatuulu Indira Kudaibergenova Maciej Banach Aibek Mirrakhimov Source Type: research
Position paper of the Polish Expert Group on the use of pitavastatin in the treatment of lipid disorders in Poland endorsed by the Polish Lipid Association
Arch Med Sci. 2023 Nov 26;20(1):28-42. doi: 10.5114/aoms/175879. eCollection 2024.ABSTRACTLipid disorders, primarily hypercholesterolemia, are the most common cardiovascular (CV) risk factor in Poland (this applies even 3/4 of people). The low-density lipoprotein cholesterol (LDL-C) serum level is the basic lipid parameter that should be measured to determine CV risk and determines the aim and target of lipid-lowering treatment (LLT). Lipid-lowering treatment improves cardiovascular prognosis and prolongs life in both primary and secondary cardiovascular prevention. Despite the availability of effective lipid-lowering drug...
Source: Archives of Medical Science - February 28, 2024 Category: General Medicine Authors: Maciej Banach Stanis ław Surma Agnieszka Kap łon-Cieślicka Przemys ław Mitkowski Grzegorz Dzida Tomasz Tomasik Agnieszka Mastalerz-Migas Source Type: research
