Putative associations between inflammatory biomarkers, obesity, and obstructive sleep apnea
CONCLUSIONS: OSA patients exhibit increased levels of inflammatory mediators that do not appear to be associated with polysomnographic measures, but exhibit positive correlation with the degree of adiposity. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - October 26, 2021 Category: Respiratory Medicine Authors: Siraj Omar Wali Md Dilshad Manzar Mohammed M Abdelaziz Ranya Alshomrani Faris Alhejaili Jamil Al-Mughales Wail Alamoudi David Gozal Source Type: research
Drug susceptibility profiling of pulmonary Mycobacterium kansasii and its correlation with treatment outcome
CONCLUSION: There was a poor correlation between the treatment outcome and the resistance pattern of the antibiotics tested. With increasing numbers of NTM being reported, early and correct identification of NTM species is essential for the prompt initiation of appropriate treatment to achieve better outcome. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - October 26, 2021 Category: Respiratory Medicine Authors: Priya Rajendran Chandrasekaran Padmapriyadarsini Vaishnavee Vijayaraghavan Tamizhselvan Manoharan Lakshana Malla Lokanathan Parveen Banu Kadhar Lavanya Jayabal Gomathy Sivaramakrishnan Source Type: research
Bilevel positive airway pressure ventilation for non-COPD acute hypercapnic respiratory failure patients: A systematic review and meta-analysis
Bandar M Faqihi, Samuel P Trethewey, Julien Morlet, Dhruv Parekh, Alice M TurnerAnnals of Thoracic Medicine 2021 16(4):306-322
The effectiveness of bi-level positive airway pressure (BiPAP) in patients with acute hypercapnic respiratory failure (AHRF) due to etiologies other than chronic obstructive pulmonary disease (COPD) is unclear. To systematically review the evidence regarding the effectiveness of BiPAP in non-COPD patients with AHRF. The Cochrane Library, MEDLINE, EMBASE, and CINAHL Plus were searched according to prespecified criteria (PROSPERO-CRD42018089875). Randomized controlled trials (RCTs) assessing the eff...
Source: Annals of Thoracic Medicine - October 26, 2021 Category: Respiratory Medicine Authors: Bandar M Faqihi Samuel P Trethewey Julien Morlet Dhruv Parekh Alice M Turner Source Type: research
Pulmonary rehabilitation for COPD: A narrative review and call for further implementation in Saudi Arabia
Abdulelah M Aldhahir, Saeed M Alghamdi, Jaber S Alqahtani, Khaled A Alqahtani, Ahmed M Al Rajah, Bedor S Alkhathlan, Sally J Singh, Swapna Mandal, John R HurstAnnals of Thoracic Medicine 2021 16(4):299-305
Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable condition, in which outcomes can be improved with careful management. Pulmonary rehabilitation (PR) comprises exercise and education, delivered by multidisciplinary teams. PR is a cost-effective management strategy in COPD patients which improves exercise performance, reduces dyspnea, reduces the risk of exacerbation, and improves healt...
Source: Annals of Thoracic Medicine - October 26, 2021 Category: Respiratory Medicine Authors: Abdulelah M Aldhahir Saeed M Alghamdi Jaber S Alqahtani Khaled A Alqahtani Ahmed M Al Rajah Bedor S Alkhathlan Sally J Singh Swapna Mandal John R Hurst Source Type: research
Fatal rapidly progressive interstitial lung disease in a patient with amyopathic dermatomyositis
Abdullah Mobeireek, Walter Conca, Shamayel Mohammed, Fahad AlObaid, Mohammad AlHajjiAnnals of Thoracic Medicine 2021 16(3):294-298
A wide spectrum of interstitial lung disease (ID) is common and is a well-established manifestation of idiopathic inflammatory myopathies. Yet, till now, the pathogenetic mechanisms are still poorly understood, classification is evolving and prognosis is variable. A refractory and rapidly aggressive form of interstitial lung disease (RPILD) associated with dermatomyositis (DM) with minimal muscle weakness and normal creatine kinase (termed clinically amyopathic DM) is increasingly being recogn...
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Abdullah Mobeireek Walter Conca Shamayel Mohammed Fahad AlObaid Mohammad AlHajji Source Type: research
Molecular detection of plasmid-derived AmpC & #946;-lactamase among clinical strains of Enterobacteriaceae in Bahrain
CONCLUSIONS: Plasmid-mediated spread of AmpC is present in clinically relevant Enterobacteriaceae species in Bahrain. Rational antimicrobial therapy against these multidrug-resistant organisms and continued surveillance of antimicrobial resistance mechanisms among the clinical isolates are recommended for optimal patient care. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Ronni Mol Joji Ali Ebrahim Al-Mahameed Thamer Al Jishi Dania Ismail Fatani Nermin K Saeed Ahmed Jaradat Hicham Ezzat Khalid Mubarak Bindayna Source Type: research
Clinical profiles associated with SARS-CoV-2 infection and complications from coronavirus disease-2019 in children from a national registry in Saudi Arabia
CONCLUSIONS: COVID-19 is usually a milder disease in children. Although having preexisting medical conditions was linked to a longer hospitalization, it was not associated with worse outcome. Continuous surveillance will allow additional characterization of the burden and outcomes of pediatric COVID-19-associated hospitalizations. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Yasir Almuzaini Fahad Alsohime Sarah Al Subaie Mohamad Hani Temsah Yousef Alsofayan Fahad Alamri Ahmed Alahmari Hadil Alahdal Hana Sonbol Rana Almaghrabi Mahmoud Nahhas Anas Khan Source Type: research
Pulmonary neuroendocrine carcinoid tumors: Is there a predictive role to the Ki 67 index ?
CONCLUSIONS: Histological type is the best predictor of prognosis in the carcinoid tumor group. In the AC subgroup, the marginal association between mortality, frequency of relapses and Ki values 67 ≥ 1.18 has clinical relevance future analyses are required to determine the real predictive value of this variable. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Ana Karina Patane Gabriela Guma Mercedes Ray & #225; Adolfo Rosales Walter Astorino Mois & #233;s Rosenberg Source Type: research
Point-of-care diagnostic lung ultrasound is highly applicable to the practice of medicine in Saudi Arabia but the current skills gap limits its use
CONCLUSIONS: Whilst POCDLUS is applicable to IM practice in Saudi Arabia, the significant skills gap preclude the provision of a POCDLUS service. As COVID-19 can cause an interstitial syndrome, our pandemic preparation response should include POCDLUS training. The current study is supported by a similar Canadian study and the international standardisation of POCDLUS training may be feasible. The findings of the current study may facilitate the development of POCDLUS training programs for internists throughout Saudi Arabia. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Rajkumar Rajendram Mamdouh Souleymane Naveed Mahmood Mubashar Kharal Mohammad AlQahtani Source Type: research
Post-COVID-19 functional status: Relation to age, smoking, hospitalization, and previous comorbidities
CONCLUSIONS: Most of the COVID-19 recovered cases have diverse degrees of functional restrictions ranging from negligible to severe based on PCFS. These restrictions were affected by age, gender, periodic influenza vaccination, smoking, duration since symptoms onset, need for oxygen or ICU admittance, and finally the presence of coexisting comorbidity. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Aliae A R Mohamed Hussein Mahmoud Saad Hossam Eldeen Zayan Mustafa Abdelsayed Mohamed Moustafa Abdel Rahman Ezzat Radwa Helmy Howaida Abd-Elaal Karim Aly Shaimaa Abdelrheem Islam Sayed Source Type: research
Small-airway disease and its reversibility in human immunodeficiency virus-infected children on highly active antiretroviral therapy: A cross-sectional study in an African setting
CONCLUSIONS: Abnormal FEF25-75 as a marker of SAD and FEV1 with a positive BDR are common in HIV-infected children. These lung function abnormalities justify long-term follow-up for these patients. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Adaeze C Ayuk Chizalu I Ndukwu Samuel N Uwaezuoke Source Type: research
The efficacy of airway pressure release ventilation in acute respiratory distress syndrome adult patients: A meta-analysis of clinical trials
CONCLUSION: In this study, using the APRV mode may improve oxygenation on day 3 and contribute to reducing the LOS in ICU. However, it is difficult to draw a clinical message about APRV, and well-designed clinical trials are required to investigate this issue. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Fatmah Othman Noura Alsagami Reem Alharbi Yara Almuammer Shatha Alshahrani Taha Ismaeil Source Type: research
The recommended amount of physical activity, sedentary behavior, and sleep duration for healthy Saudis: A joint consensus statement of the Saudi Public Health Authority
CONCLUSIONS: Several research gaps in physical activity, sedentary behavior, and sleep were identified and highlighted by the guideline development panel for potential future research. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Rasha A Alfawaz Ghadeer S Aljuraiban Mezna A AlMarzooqi Abdullah F Alghannam Ahmed S BaHammam Ali M Dobia Shaima A Alothman Osama Aljuhani Khalid Saad Aljaloud Source Type: research
Joint consensus statement of the Saudi Public Health Authority on the recommended amount of physical activity, sedentary behavior, and sleep duration for healthy Saudis: Background, methodology, and discussion
Ahmed S BaHammam, Abdullah F Alghannam, Khalid Saad Aljaloud, Ghadeer S Aljuraiban, Mezna A AlMarzooqi, Ali M Dobia, Shaima A Alothman, Osama Aljuhani, Rasha A AlfawazAnnals of Thoracic Medicine 2021 16(3):225-238
The Saudi Public Health Authority recently prepared a Consensus Statement regarding how much time a person should spend engaged in physical activity, sedentary behavior, and sleep to promote optimal health across all age groups. This paper describes the background literature, methodology, and modified RAND Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-ADOLO...
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Ahmed S BaHammam Abdullah F Alghannam Khalid Saad Aljaloud Ghadeer S Aljuraiban Mezna A AlMarzooqi Ali M Dobia Shaima A Alothman Osama Aljuhani Rasha A Alfawaz Source Type: research
Gone with the wind! Changes in the practice of bronchoscopy post pandemic: A perspective
Himanshu Deshwal, Atul C Mehta, Mohammed MunavvarAnnals of Thoracic Medicine 2021 16(3):221-224 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 20, 2021 Category: Respiratory Medicine Authors: Himanshu Deshwal Atul C Mehta Mohammed Munavvar Source Type: research
