When single-inhaler triple therapy is a preferred option in asthma management ?
Mohamed S Al-Moamary, Riyad Al-Lehebi, Majdy M Idrees, Mohammed O ZeitouniAnnals of Thoracic Medicine 2022 17(4):185-188
Asthma control is the main goal of management. Unfortunately, most asthma patients with moderate–severe asthma remain uncontrolled despite receiving standard treatment of inhaled corticosteroids (ICS) with long-acting β2 agonists (LABA). The addition of long-acting antimuscarinic agents (LAMA) has been shown to improve different aspects of asthma control, including symptoms, lung functions, and probably exacerbations. Such an option could be considered for low-T2 asthma phenotyp...
Source: Annals of Thoracic Medicine - October 7, 2022 Category: Respiratory Medicine Authors: Mohamed S Al-Moamary Riyad Al-Lehebi Majdy M Idrees Mohammed O Zeitouni Source Type: research
A pilot study of intraoperative intercostal nerve block during uniportal thoracoscopic wedge resection of the lung
CONCLUSION: The intraoperative intercostal nerve block with bupivacaine provided immediate postoperative pain relief with reducing the postoperative opioid consumption compared in patients who underwent uniportal VATS, especially wedge resection of the lung. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 9, 2022 Category: Respiratory Medicine Authors: Do Kyun Kang Min Kyun Kang Source Type: research
Application of three-dimensional reconstruction technology combined with three-dimensional printing in the treatment of pectus excavatum
CONCLUSIONS: 3D reconstruction technology combined with 3D printing, which can be used before operation, contributes to the operator performing thoracoscopic-assisted Nuss operation safely and effectively, which has productive clinical application value for the treatment of pectus excavatum. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 9, 2022 Category: Respiratory Medicine Authors: Yibo Shan Guiping Yu Yi Lu Hao Kong Xuewei Jiang Zhiming Shen Fei Sun Hongcan Shi Source Type: research
Continuous positive airway pressure therapy suppresses inflammatory cytokines and improves glucocorticoid responsiveness in patients with obstructive sleep apnea and asthma: A case & #8211;control study
CONCLUSIONS: Continuous positive airway pressure therapy improved responsiveness to glucocorticoid treatment and demonstrated a suppressive effect on proinflammatory cytokines in asthmatics with OSA. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 9, 2022 Category: Respiratory Medicine Authors: Bassam Mahboub Zelal Kharaba Rakhee K Ramakrishnan Narjes Saheb Sharif Askari Laila Ibraheem Salameh Hassan Saber Alhariri Mayank G Vats Wafa Taleb Erabia Esra & #39;a Mohammad Alshawamreh Yassen Alfoteih Andrea K Mogas Rabih Halwani Qutayba Hamid Source Type: research
The optimal oral body temperature cutoff and other factors predictive of sepsis diagnosis in elderly patients
CONCLUSION: The risk factors of sepsis such as age, temperature, and seasonal variation inform important evidence-based decisions. The hospitals dealing with sepsis patients should assess older patients for other severe illnesses or co-morbid that might lead to sepsis if left untreated. Therefore, older patients need to be prioritized over younger patients. The body temperature of patients admitted to hospitals needs to be monitored critically and it is important to consider seasonal fluctuations while managing cases of sepsis and allocating resources. Our findings suggest that clinicians should explore the possibility of ...
Source: Annals of Thoracic Medicine - July 9, 2022 Category: Respiratory Medicine Authors: Majid Alsalamah Bashaer Alrehaili Amal Almoamary Abdulrahman Al-Juad Mutasim Badri Ashraf El-Metwally Source Type: research
Comparison of radial endobronchial ultrasound-guided transbronchial lung biopsy with distance measurement versus with guide sheath in diagnosing peripheral pulmonary lesions with a diameter & #8805;3 cm by thin bronchoscope
CONCLUSION: REBUS-D-TBLB by thin bronchoscope has a high diagnostic value for PPL with a diameter ≥3 cm, which may be considered a useful alternative for rEBUS-GS-TBLB in the clinic. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 9, 2022 Category: Respiratory Medicine Authors: Shuhong Guan Jun Zhou Qiudi Zhang Qianqian Xu Xiong Xu Sujuan Zhang Source Type: research
Fibrinolysis versus thoracoscopy: Comparison of results in empyema management in the child
CONCLUSIONS: In our experience, the results obtained with both procedures are quite similar, although patients undergoing TS had a better evolution (fewer days of antibiotic and a tendency to less hospitalization), despite having been performed a priori in more evolved patients. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 9, 2022 Category: Respiratory Medicine Authors: Maria Rosa Ibarra Rodriguez Jose Ignacio Garrido P & #233;rez Fernando V & #225;zquez Rueda Francisco Javier Murcia Pascual Sandra Rocio Wiesner Torres Rosa Maria Paredes Esteban Source Type: research
Post-COVID lung disease(s)
Michel Achkar, Omar Jamal, Toufic ChaabanAnnals of Thoracic Medicine 2022 17(3):137-144
Post-COVID lung impairment and diseases are major public health concern in the pandemic of COVID-19. Multiple etiological factors can lead to post-COVID respiratory symptoms, with post COVID fibrosis or diffuse parenchymal lung disease being the major concern. We searched PubMed database for English literature related to post-COVID lung disease and we summarized the existing evidence on radiological, physiological, and histopathological aspects of post-COVID lung diseases. We suggest a guidance on the evaluation of these patients and h...
Source: Annals of Thoracic Medicine - July 9, 2022 Category: Respiratory Medicine Authors: Michel Achkar Omar Jamal Toufic Chaaban Source Type: research
Difficulties in the treatment of an infant survivor with inherited surfactant protein-B deficiency in Tunisia
Samia Hamouda, Ines Trabelsi, Alix de Becdelièvre, Khadija BoussettaAnnals of Thoracic Medicine 2022 17(2):132-135
A female-term neonate showed a severe respiratory distress syndrome (RDS) at hour 3 of life requiring her transfer to intensive care. She was intubated and started on assist-control mechanical ventilation associated with inhaled nitric oxide then high-frequency oscillation ventilation at day 12. Chest X-ray was gradually deteriorating. Chest computed tomography (CT) scan revealed diffuse interstitial lung disease. Flexible bronchoscopy excluded pulmonary alveolar proteinosis. The genetics study co...
Source: Annals of Thoracic Medicine - April 19, 2022 Category: Respiratory Medicine Authors: Samia Hamouda Ines Trabelsi Alix de Becdeli & #232;vre Khadija Boussetta Source Type: research
Diagnostic value of bronchoscopy in sputum-negative pulmonary tuberculosis patients and its correlation with clinicoradiological features
CONCLUSIONS: An overall diagnostic yield of 90% was achieved with combined use of BAL MTB PCR, culture, and histopathology. Upper lobe lavage and presence of cavities on chest imaging had a higher diagnostic yield. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - April 19, 2022 Category: Respiratory Medicine Authors: Sadia Imtiaz Enas Mansour Batubara Source Type: research
Obstructive sleep apnea in patients with severe asthma: Prevalence and association between severity and asthma control
CONCLUSIONS: The prevalence of OSA was high (32.37%) in patients with severe asthma. Uncontrolled severe asthma was significantly associated with severe OSA. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - April 19, 2022 Category: Respiratory Medicine Authors: Fatema Al-Lawati Saif M Al-Mubaihsi B Jayakrishnan Sayed Rizvi Mohammed A Al-Abri Source Type: research
The effectiveness of POST-DISCHARGE telerehabilitation practices in COVID-19 patients: Tele-COVID study-randomized controlled trial
CONCLUSION: Telerehabilitation exercise program with less technical equipment is a good alternative treatment method for COVID-19 subjects, which improves the quality of life and symptomatic status of subjects.
Clinical Trial Registration Number: nct04402983 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - April 19, 2022 Category: Respiratory Medicine Authors: Esra Pehlivan & #304;smail Palal & #305; Sibel Gayretli Atan Demet Turan Halit & #199; & #305;narka Erdo & #287;an & #199;etinkaya Source Type: research
The association of timing of pharmacological prophylaxis and venous thromboembolism in patients with moderate-to-severe traumatic brain injury: A retrospective cohort study
CONCLUSIONS: Late prophylaxis (>72 h) was associated with higher VTE rate in patients with moderate-to-severe TBI, but not with higher mortality. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - April 19, 2022 Category: Respiratory Medicine Authors: Hasan M Al-Dorzi Ghadah Al-Yami Fatima Al-Daker Muhannad Q Alqirnas Moustafa S Alhamadh Raymond Khan Source Type: research
Evaluation of risk stratification and adherence to venous thromboembolism prophylaxis among hospitalized obstetric women: Retrospective case file review at East Jeddah Hospital during 2018 & #8211;2019
CONCLUSION: There was a considerable VTE risk among hospitalized obstetric patients which peaked during the postnatal period. Physicians showed good compliance to local VTE protocol with no reported VTE events or drug-induced bleeding. However, the implementation of prophylaxis is associated with both under and overutilization. There is a need for increasing the physicians' awareness of optimizing VTE risk assessment and documentation for hospitalized obstetric patients. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - April 19, 2022 Category: Respiratory Medicine Authors: Ghadeer Mattar Nada Al Sahafi Lujain Al Hazmi Nadia Al Hazmi Hanaa Elsayed Abozeid Intessar Sultan Source Type: research
Pathophysiology and rehabilitation management of exercise intolerance in COVID-19 patients
DISCUSSION: Exercise intolerance is caused by some pathological processes in the respiratory, cardiovascular, and musculoskeletal systems as a result of systemic inflammation. Fatigue and shortness of breath during the activity were the most common symptom in the early phase of COVID-19 and persisted until the follow-up phase. Hospital admission, especially prolonged use of ventilators and immobilization worsen functional impairment resulting in persistent symptoms. Rehabilitation management begins with a functional assessment consisting of symptom assessment and physical examination of the body systems affected. The goals...
Source: Annals of Thoracic Medicine - April 19, 2022 Category: Respiratory Medicine Authors: Arnengsih Nazir Indra Putera Hasri Source Type: research
