How Would You Manage HIV Pre-exposure Prophylaxis in This Patient With Medical Comorbidities? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center
Ann Intern Med. 2024 Apr 9. doi: 10.7326/M24-0217. Online ahead of print.ABSTRACTDespite advances in treatment, HIV infection remains an important cause of morbidity and mortality, with more than 30 000 new cases diagnosed in the United States each year. There are several interventions traditionally used to prevent HIV transmission, but these vary in effectiveness and there are challenges to their implementation. In 2014, the Centers for Disease Control and Prevention published initial guidance on the use of antiretroviral pre-exposure prophylaxis (PrEP) to prevent transmission of HIV infection in persons at risk based on ...
Source: Annals of Internal Medicine - April 8, 2024 Category: Internal Medicine Authors: Howard Libman Douglas Krakower Jessica L Taylor Risa B Burns Source Type: research
Trends in U.S. Medical Cannabis Registrations, Authorizing Clinicians, and Reasons for Use From 2020 to 2022
CONCLUSION: Enrollment in medical cannabis programs increased overall but generally decreased in jurisdictions with nonmedical adult-use laws. Use for conditions or symptoms without a strong evidence basis continues to increase. Given these trends, more research is needed to better understand the risks and benefits of medical cannabis.PRIMARY FUNDING SOURCE: National Institute on Drug Abuse of the National Institutes of Health.PMID:38588545 | DOI:10.7326/M23-2811 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 8, 2024 Category: Internal Medicine Authors: Kevin F Boehnke Rachel Sinclair Felicia Gordon Avinash Hosanagar Douglas R Roehler Tristin Smith Brooke Hoots Source Type: research
Long-Term Effect of Salt Substitution for Cardiovascular Outcomes : A Systematic Review and Meta-Analysis
CONCLUSION: Salt substitution may reduce all-cause or cardiovascular mortality, but the evidence for reducing cardiovascular events and for not increasing serious adverse events is uncertain, particularly for a Western population. The certainty of evidence is higher among populations at higher cardiovascular risk and/or following a Chinese diet.PRIMARY FUNDING SOURCE: National Health and Medical Research Council. (PROSPERO: CRD42022327566).PMID:38588546 | DOI:10.7326/M23-2626 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 8, 2024 Category: Internal Medicine Authors: Hannah Greenwood Katelyn Barnes Justin Clark Lauren Ball Loai Albarqouni Source Type: research
Screening for Colorectal Cancer
Ann Intern Med. 2024 Apr 9. doi: 10.7326/AITC202404160. Online ahead of print.ABSTRACTColorectal cancer (CRC) is the second leading cause of cancer death. Screening has been proven to reduce both cancer incidence and cancer-related mortality. Various screening tests are available, each with their own advantages and disadvantages and varying levels of evidence to support their use. Clinicians should offer CRC screening to average-risk persons aged 50 to 75 years; starting screening at age 45 years remains controversial. Screening may be beneficial in select persons aged 76 to 85 years, based on their overall health and scre...
Source: Annals of Internal Medicine - April 8, 2024 Category: Internal Medicine Authors: Swati G Patel Jason A Dominitz Source Type: research
In adults with post-COVID-19 conditions, a synbiotic preparation, SIM01, alleviated some symptoms at 6 mo
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0018. Online ahead of print.ABSTRACTLau RI, Su Q, Lau IS, et al. A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial. Lancet Infect Dis. 2024;24:256-265. 38071990.PMID:38560898 | DOI:10.7326/J24-0018 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Deepa Gotur Eleftherios Mylonakis Source Type: research
