New use of thiazide diuretics vs. nonthiazide antihypertensive drugs was linked to hyponatremia over 2 y
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0021. Online ahead of print.ABSTRACTAndersson NW, Wohlfahrt J, Feenstra B, et al. Cumulative incidence of thiazide-induced hyponatremia: a population-based cohort study. Ann Intern Med. 2024;177:1-11. 38109740.PMID:38710078 | DOI:10.7326/J24-0021 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Mansi Mehta David S Goldfarb Source Type: research

In community-acquired pneumonia, adding oral clarithromycin to standard care increased early clinical response
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0022. Online ahead of print.ABSTRACTGiamarellos-Bourboulis EJ, Siampanos A, Bolanou A, et al. Clarithromycin for early anti-inflammatory responses in community-acquired pneumonia in Greece (ACCESS): a randomised, double-blind, placebo-controlled trial. Lancet Respir Med. 2024;12:294-304. 38184008.PMID:38710079 | DOI:10.7326/J24-0022 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Henry S Sacks Source Type: research

Reversal of Intestinal Failure With Teduglutide in < em > PERCC1 < /em > -Associated Enteropathy: A Case Report
Ann Intern Med. 2024 May 7. doi: 10.7326/M24-0147. Online ahead of print.NO ABSTRACTPMID:38710080 | DOI:10.7326/M24-0147 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Emily Stenke Cara Dunne Anthea Bryce-Smyth Michelle Hurley Ben Pode-Shakked Yair Anikster Tricia Tan Anna Kowalka Paul Bech Billy Bourke Source Type: research

In AF, CHA < sub > 2 < /sub > DS < sub > 2 < /sub > -VASc 1 subgroups did not differ for predicting risk for arterial thromboembolism at 1 y
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0023. Online ahead of print.ABSTRACTØstergaard L, Olesen JB, Petersen JK, et al. Arterial thromboembolism in patients with atrial fibrillation and CHA2DS2-VASc 1: a nationwide study. Circulation. 2024;149:764-773. 38152890.PMID:38710081 | DOI:10.7326/J24-0023 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Luciano A Sposato Michael D Hill Source Type: research

In older patients with AF and frailty, switching from VKA to NOAC therapy increased a composite of major or CRNM bleeding at 12 mo
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0024. Online ahead of print.ABSTRACTJoosten LP, van Doorn S, van de Ven PM, et al. Safety of switching from a vitamin K antagonist to a non-vitamin K antagonist oral anticoagulant in frail older patients with atrial fibrillation: results of the FRAIL-AF randomized controlled trial. Circulation. 2024;149:279-289. 37634130.PMID:38710082 | DOI:10.7326/J24-0024 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Andrew Dunn Source Type: research

In HFpEF with obesity, semaglutide improved health status and weight loss at 52 wk, regardless of initial health status
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0025. Online ahead of print.ABSTRACTKosiborod MN, Verma S, Borlaug BA, et al; STEP-HFpEF Trial Committees and Investigators. Effects of semaglutide on symptoms, function, and quality of life in patients with heart failure with preserved ejection fraction and obesity: a prespecified analysis of the STEP-HFpEF trial. Circulation. 2024;149:204-216. 37952180.PMID:38710083 | DOI:10.7326/J24-0025 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Darren Lau Source Type: research

Update Alert: Effectiveness and Safety of Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis: A Living Systematic Review and Network Meta-analysis for the American College of Physicians
Ann Intern Med. 2024 May 7. doi: 10.7326/L24-0118. Online ahead of print.NO ABSTRACTPMID:38710084 | DOI:10.7326/L24-0118 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Chelsea Ayers Rachel Ward Devan Kansagara Source Type: research

In patients with type 2 diabetes and recent MI, colchicine reduced a composite CV outcome at 23 mo
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0026. Online ahead of print.ABSTRACTRoubille F, Bouabdallaoui N, Kouz S, et al. Low-dose colchicine in patients with type 2 diabetes and recent myocardial infarction in the COLchicine Cardiovascular Outcomes Trial (COLCOT). Diabetes Care. 2024;47:467-470. 38181203.PMID:38710085 | DOI:10.7326/J24-0026 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Eric R Bates Source Type: research

The Safety of Outpatient Health Care : Review of Electronic Health Records
CONCLUSION: Outpatient harm was relatively common and often serious. Adverse drug events were most frequent. Rates were higher among older adults. Interventions to curtail outpatient harm are urgently needed.PRIMARY FUNDING SOURCE: Controlled Risk Insurance Company and the Risk Management Foundation of the Harvard Medical Institutions.PMID:38710086 | DOI:10.7326/M23-2063 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: David M Levine Ania Syrowatka Hojjat Salmasian David M Shahian Stuart Lipsitz Jonathan P Zebrowski Laura C Myers Merranda S Logan Christopher G Roy Christine Iannaccone Michelle L Frits Lynn A Volk Sevan Dulgarian Mary G Amato Heba H Edrees Luke Sato Patr Source Type: research

The More Things Change, the More They Stay the Same: Understanding the Safety of Outpatient Care
Ann Intern Med. 2024 May 7. doi: 10.7326/M24-0876. Online ahead of print.NO ABSTRACTPMID:38710087 | DOI:10.7326/M24-0876 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Urmimala Sarkar Source Type: research

SCCM issued recommendations for corticosteroid use in acutely ill adults with sepsis, ARDS, or CAP
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0027. Online ahead of print.ABSTRACTChaudhuri D, Nei AM, Rochwerg B, et al. 2024 focused update: guidelines on use of corticosteroids in sepsis, acute respiratory distress syndrome, and community-acquired pneumonia. Crit Care Med. 2024;52:e219-e233. 38240492.PMID:38710088 | DOI:10.7326/J24-0027 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Rodolfo A Estrada Marcos I Restrepo Source Type: research

In type 2 diabetes, the effectiveness and side effects of GLP-1 RAs vary
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0028. Online ahead of print.ABSTRACTYao H, Zhang A, Li D, et al. Comparative effectiveness of GLP-1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta-analysis. BMJ. 2024;384:e076410. 38286487.PMID:38710089 | DOI:10.7326/J24-0028 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Clare O'Brien Sean F Dinneen Source Type: research

Annals On Call - A Resurgence of Dengue
Ann Intern Med. 2024 May 7:eA240003. doi: 10.7326/A24-0003. Online ahead of print.NO ABSTRACTPMID:38710090 | DOI:10.7326/A24-0003 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Robert M Centor Davidson H Hamer Ralph Huits Source Type: research

Why Hospitals Must Provide Abortions in Pregnancy Emergencies
Ann Intern Med. 2024 May 7. doi: 10.7326/M24-0276. Online ahead of print.NO ABSTRACTPMID:38710091 | DOI:10.7326/M24-0276 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Abram Brummett Riya Chhabra Deepali Tailor Source Type: research

In < em > Enterobacterales < /em > bacteremia, antipseudomonal β-lactam de-escalation was noninferior to continuation for clinical cure at 3 to 5 d
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0030. Online ahead of print.ABSTRACTLópez-Cortés LE, Delgado-Valverde M, Moreno-Mellado E, et al; SIMPLIFY study group. Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (SIMPLIFY): an open-label, multicentre, randomised trial. Lancet Infect Dis. 2024;24:375-385. 38215770.PMID:38710092 | DOI:10.7326/J24-0030 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Konstantinos Ouranos Eleftherios Mylonakis Source Type: research