Association of Albuminuria With Chronic Kidney Disease Progression in Persons With Chronic Kidney Disease and Normoalbuminuria : A Cohort Study
CONCLUSION: Persons with CKD and normoalbuminuria (<30 mg/g) had excess risk for CKD progression, which increased in a linear fashion with higher levels of albuminuria.PRIMARY FUNDING SOURCE: None.PMID:38560911 | DOI:10.7326/M23-2814 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Ashish Verma Insa M Schmidt Sophie Claudel Ragnar Palsson Sushrut S Waikar Anand Srivastava Source Type: research
Annals On Call - Improving Research Reports: Avoiding < em > P < /em > Values
Ann Intern Med. 2024 Apr 2:eA240001. doi: 10.7326/A24-0001. Online ahead of print.NO ABSTRACTPMID:38560912 | DOI:10.7326/A24-0001 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Robert M Centor David A Savitz Source Type: research
In CKD, empagliflozin reduced kidney disease progression at a median 2 y, regardless of primary kidney disease type
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0020. Online ahead of print.ABSTRACTEMPA-KIDNEY Collaborative Group. Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial. Lancet Diabetes Endocrinol. 2024;12:51-60. 38061372.PMID:38560913 | DOI:10.7326/J24-0020 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Jin Ho Hwang Chi-Yuan Hsu Source Type: research
Disparities in Tuberculosis Incidence by Race and Ethnicity Among the U.S.-Born Population in the United States, 2011 to 2021 : An Analysis of National Disease Registry Data
CONCLUSION: There are persistent disparities in TB incidence by race/ethnicity. Relative disparities were greater for AI/AN persons, females, and younger persons, and absolute disparities were greater for males. Eliminating these disparities could reduce overall TB incidence by more than 60% among the U.S.-born population.PRIMARY FUNDING SOURCE: Centers for Disease Control and Prevention.PMID:38560914 | DOI:10.7326/M23-2975 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Yunfei Li Mathilda Regan Nicole A Swartwood Terrika Barham Garrett R Beeler Asay Ted Cohen Andrew N Hill C Robert Horsburgh Awal Khan Suzanne M Marks Ranell L Myles Joshua A Salomon Julie L Self Nicolas A Menzies Source Type: research
In adults with post-COVID-19 conditions, a synbiotic preparation, SIM01, alleviated some symptoms at 6 mo
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0018. Online ahead of print.ABSTRACTLau RI, Su Q, Lau IS, et al. A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial. Lancet Infect Dis. 2024;24:256-265. 38071990.PMID:38560898 | DOI:10.7326/J24-0018 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Deepa Gotur Eleftherios Mylonakis Source Type: research
For due or overdue cervical cancer screening, direct or opt-in mailing of HPV self-sampling increased screening at 6 mo vs. education
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0019. Online ahead of print.ABSTRACTWiner RL, Lin J, Anderson ML, et al. Strategies to increase cervical cancer screening with mailed human papillomavirus self-sampling kits: a randomized clinical trial. JAMA. 2023;330:1971-1981. 38015219.PMID:38560899 | DOI:10.7326/J24-0019 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Pelin Batur Source Type: research
Management of Inpatient Elevated Blood Pressures : A Systematic Review of Clinical Practice Guidelines
CONCLUSION: Despite general consensus on outpatient BP management, guidance on inpatient management of elevated BP without symptoms is lacking, which may contribute to variable practice patterns.PRIMARY FUNDING SOURCE: National Institute on Aging. (PROSPERO: CRD42023449250).PMID:38560900 | DOI:10.7326/M23-3251 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Linnea M Wilson Shoshana J Herzig Michael A Steinman Mara A Schonberg Jennifer L Cluett Edward R Marcantonio Timothy S Anderson Source Type: research
Development of a Multivariable Model to Predict the Need for Bone Marrow Sampling in Persons With Monoclonal Gammopathy of Undetermined Significance : A Cohort Study Nested in a Clinical Trial
CONCLUSION: This accurate prediction model for SMM or worse was developed in a population-based cohort of persons with presumed MGUS and may be used to defer bone marrow sampling and referral to hematology.PRIMARY FUNDING SOURCE: International Myeloma Foundation and the European Research Council.PMID:38560901 | DOI:10.7326/M23-2540 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Elias Eythorsson Saemundur Rognvaldsson Sigrun Thorsteinsdottir Thorir Einarsson Long Elin Ruth Reed Gudrun Asta Sigurdardottir Brynjar Vidarsson Pall Torfi Onundarson Bjarni A Agnarsson Margret Sigurdardottir Isleifur Olafsson Ingunn Thorsteinsdottir Sig Source Type: research
In patients with coma due to acute poisoning, withholding intubation improved clinical outcomes
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0011. Online ahead of print.ABSTRACTFreund Y, Viglino D, Cachanado M, et al. Effect of noninvasive airway management of comatose patients with acute poisoning: a randomized clinical trial. JAMA. 2023;330:2267-2274. 38019968.PMID:38560902 | DOI:10.7326/J24-0011 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Evan S Schwarz Source Type: research
In suspected ACS, hs-cTnI- vs. c-cTnI-guided care was associated with improved outcomes at 5 y in certain subgroups
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0012. Online ahead of print.ABSTRACTLee KK, Doudesis D, Ferry AV, et al; High-STEACS Investigators. Implementation of a high sensitivity cardiac troponin I assay and risk of myocardial infarction or death at five years: observational analysis of a stepped wedge, cluster randomised controlled trial. BMJ. 2023;383:e075009. 38011922.PMID:38560903 | DOI:10.7326/J24-0012 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Jonathan Kirschner Benton Hunter Source Type: research
In solid tumors, neoadjuvant or adjuvant immune checkpoint blockade increases treatment-related grade 3 or 4 adverse events
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0013. Online ahead of print.ABSTRACTFujiwara Y, Horita N, Adib E, et al. Treatment-related adverse events, including fatal toxicities, in patients with solid tumours receiving neoadjuvant and adjuvant immune checkpoint blockade: a systematic review and meta-analysis of randomised controlled trials. Lancet Oncol. 2024;25:62-75. 38012893.PMID:38560904 | DOI:10.7326/J24-0013 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Luca Bertolaccini Source Type: research
In severe eosinophilic asthma controlled with benralizumab, tapering high-dose ICS reduced dose while maintaining control
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0014. Online ahead of print.ABSTRACTJackson DJ, Heaney LG, Humbert M, et al; SHAMAL Investigators. Reduction of daily maintenance inhaled corticosteroids in patients with severe eosinophilic asthma treated with benralizumab (SHAMAL): a randomised, multicentre, open-label, phase 4 study. Lancet. 2024;403:271-281. 38071986.PMID:38560905 | DOI:10.7326/J24-0014 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Matthew B Stanbrook Source Type: research
Beyond the Bacillus: Closing Gaps in Tuberculosis Health Disparities Requires Targeting Social Determinants
Ann Intern Med. 2024 Apr 2. doi: 10.7326/M24-0548. Online ahead of print.NO ABSTRACTPMID:38560906 | DOI:10.7326/M24-0548 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Kenneth G Castro N Sarita Shah Source Type: research
In T2DM, periconceptional, noninsulin, second-line antidiabetes medications were not linked to major congenital malformations vs. insulin
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0015. Online ahead of print.ABSTRACTCesta CE, Rotem R, Bateman BT, et al. Safety of GLP-1 receptor agonists and other second-line antidiabetics in early pregnancy. JAMA Intern Med. 2024;184:144-152. 38079178.PMID:38560907 | DOI:10.7326/J24-0015 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Aoife M Egan Source Type: research
In higher-risk, statin-intolerant adults with diabetes, bempedoic acid reduced MACE at a median 3 y
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0016. Online ahead of print.ABSTRACTRay KK, Nicholls SJ, Li N, et al; CLEAR OUTCOMES Committees and Investigators. Efficacy and safety of bempedoic acid among patients with and without diabetes: prespecified analysis of the CLEAR Outcomes randomised trial. Lancet Diabetes Endocrinol. 2024;12:19-28. 38061370.PMID:38560908 | DOI:10.7326/J24-0016 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Michelle Kelsey L Kristin Newby Source Type: research
