Reply to Chen et al.: Reexamining COPD in Bronchiectasis: Elucidating Overdiagnosis and Outcomes from EMBARC's ROSE Criteria
Am J Respir Crit Care Med. 2024 Apr 5. doi: 10.1164/rccm.202403-0476LE. Online ahead of print.NO ABSTRACTPMID:38579281 | DOI:10.1164/rccm.202403-0476LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 5, 2024 Category: Intensive Care Authors: James D Chalmers Anthony De Soyza Stefano Aliberti Eva Polverino Source Type: research
Reexamining COPD in Bronchiectasis: Elucidating Overdiagnosis and Outcomes from EMBARC's ROSE Criteria
Am J Respir Crit Care Med. 2024 Apr 5. doi: 10.1164/rccm.202402-0289LE. Online ahead of print.NO ABSTRACTPMID:38579279 | DOI:10.1164/rccm.202402-0289LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 5, 2024 Category: Intensive Care Authors: Yen-Fu Chen Jung-Yien Chien Hao-Chien Wang Chong-Jen Yu Source Type: research
Reply to Chen et al.: Reexamining COPD in Bronchiectasis: Elucidating Overdiagnosis and Outcomes from EMBARC's ROSE Criteria
Am J Respir Crit Care Med. 2024 Apr 5. doi: 10.1164/rccm.202403-0476LE. Online ahead of print.NO ABSTRACTPMID:38579281 | DOI:10.1164/rccm.202403-0476LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 5, 2024 Category: Intensive Care Authors: James D Chalmers Anthony De Soyza Stefano Aliberti Eva Polverino Source Type: research
Reexamining COPD in Bronchiectasis: Elucidating Overdiagnosis and Outcomes from EMBARC's ROSE Criteria
Am J Respir Crit Care Med. 2024 Apr 5. doi: 10.1164/rccm.202402-0289LE. Online ahead of print.NO ABSTRACTPMID:38579279 | DOI:10.1164/rccm.202402-0289LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 5, 2024 Category: Intensive Care Authors: Yen-Fu Chen Jung-Yien Chien Hao-Chien Wang Chong-Jen Yu Source Type: research
Reply to Chen et al.: Reexamining COPD in Bronchiectasis: Elucidating Overdiagnosis and Outcomes from EMBARC's ROSE Criteria
Am J Respir Crit Care Med. 2024 Apr 5. doi: 10.1164/rccm.202403-0476LE. Online ahead of print.NO ABSTRACTPMID:38579281 | DOI:10.1164/rccm.202403-0476LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 5, 2024 Category: Intensive Care Authors: James D Chalmers Anthony De Soyza Stefano Aliberti Eva Polverino Source Type: research
Reexamining COPD in Bronchiectasis: Elucidating Overdiagnosis and Outcomes from EMBARC's ROSE Criteria
Am J Respir Crit Care Med. 2024 Apr 5. doi: 10.1164/rccm.202402-0289LE. Online ahead of print.NO ABSTRACTPMID:38579279 | DOI:10.1164/rccm.202402-0289LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 5, 2024 Category: Intensive Care Authors: Yen-Fu Chen Jung-Yien Chien Hao-Chien Wang Chong-Jen Yu Source Type: research
Reply to Chen et al.: Reexamining COPD in Bronchiectasis: Elucidating Overdiagnosis and Outcomes from EMBARC's ROSE Criteria
Am J Respir Crit Care Med. 2024 Apr 5. doi: 10.1164/rccm.202403-0476LE. Online ahead of print.NO ABSTRACTPMID:38579281 | DOI:10.1164/rccm.202403-0476LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 5, 2024 Category: Intensive Care Authors: James D Chalmers Anthony De Soyza Stefano Aliberti Eva Polverino Source Type: research
Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine
Am J Respir Crit Care Med. 2024 Apr 4. doi: 10.1164/rccm.202401-0238SO. Online ahead of print.ABSTRACTRecent genetic and genomic advancements have elucidated the complex etiology of idiopathic pulmonary fibrosis (IPF) and other progressive fibrotic interstitial lung diseases (ILDs), emphasizing the contribution of heritable factors. This state-of-the-art review synthesizes evidence on significant genetic contributors to pulmonary fibrosis (PF), including rare genetic variants and common single nucleotide polymorphisms (SNPs). The MUC5B promoter variant is unusual, a common SNP that markedly elevates the risk of early and e...
Source: Am J Respir Crit Car... - April 4, 2024 Category: Intensive Care Authors: Ayodeji Adegunsoye Jonathan A Kropski Juergen Behr Timothy S Blackwell Tamera J Corte Vincent Cottin Allan Glanville Marilyn K Glassberg Matthias Griese Gary M Hunninghake Kerri A Johannson Michael P Keane John S Kim Martin Kolb Toby M Maher Justin M Oldh Source Type: research
Pulmonary Ionocytes Regulate Airway Surface Liquid pH in Primary Human Bronchial Epithelial Cells
Conclusions: We conclude that ionocytes do not contribute to ASL formation but regulate ASL pH. Club cells secrete the bulk of airway fluid. In CF, abnormal ionocyte and club cell function results in acidic and dehydrated ASL, causing reduced antimicrobial properties and mucociliary clearance. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).PMID:38573173 | DOI:10.1164/rccm.202309-1565OC (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 4, 2024 Category: Intensive Care Authors: Xiaojie Luan Nicolas Henao Romero Veronica A Campanucci Yen Le Jannatul Mustofa Julian S Tam Juan P Ianowski Source Type: research
"A Mighty Flame Can Follow a Tiny Spark": Is This the Case of C-Jun N-Terminal Kinase 1 (JNK) Inhibitors in Idiopathic Pulmonary Fibrosis?
Am J Respir Crit Care Med. 2024 Apr 4. doi: 10.1164/rccm.202403-0574ED. Online ahead of print.NO ABSTRACTPMID:38574193 | DOI:10.1164/rccm.202403-0574ED (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 4, 2024 Category: Intensive Care Authors: Fabrizio Luppi Giovanni Ferrara Source Type: research
Why Home-NIV Should Begin in the Hospital, Not at Home
Am J Respir Crit Care Med. 2024 Apr 4. doi: 10.1164/rccm.202401-0214VP. Online ahead of print.NO ABSTRACTPMID:38574196 | DOI:10.1164/rccm.202401-0214VP (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 4, 2024 Category: Intensive Care Authors: Spyridon Fortis Source Type: research
Reply to Mozaffaripour < em > et al. < /em > : Dose Modulation, BMI and CT-Air Trapping
Am J Respir Crit Care Med. 2024 Apr 4. doi: 10.1164/rccm.202402-0453LE. Online ahead of print.NO ABSTRACTPMID:38574365 | DOI:10.1164/rccm.202402-0453LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 4, 2024 Category: Intensive Care Authors: Clarus Leung Sean B Fain Eric A Hoffman John V Fahy Source Type: research
Dose Modulation, BMI and CT-Air Trapping
Am J Respir Crit Care Med. 2024 Apr 4. doi: 10.1164/rccm.202402-0353LE. Online ahead of print.NO ABSTRACTPMID:38574369 | DOI:10.1164/rccm.202402-0353LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 4, 2024 Category: Intensive Care Authors: Ali Mozaffaripour Harkiran K Kooner Grace Parraga Source Type: research
Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine
Am J Respir Crit Care Med. 2024 Apr 4. doi: 10.1164/rccm.202401-0238SO. Online ahead of print.ABSTRACTRecent genetic and genomic advancements have elucidated the complex etiology of idiopathic pulmonary fibrosis (IPF) and other progressive fibrotic interstitial lung diseases (ILDs), emphasizing the contribution of heritable factors. This state-of-the-art review synthesizes evidence on significant genetic contributors to pulmonary fibrosis (PF), including rare genetic variants and common single nucleotide polymorphisms (SNPs). The MUC5B promoter variant is unusual, a common SNP that markedly elevates the risk of early and e...
Source: Am J Respir Crit Car... - April 4, 2024 Category: Intensive Care Authors: Ayodeji Adegunsoye Jonathan A Kropski Juergen Behr Timothy S Blackwell Tamera J Corte Vincent Cottin Allan Glanville Marilyn K Glassberg Matthias Griese Gary M Hunninghake Kerri A Johannson Michael P Keane John S Kim Martin Kolb Toby M Maher Justin M Oldh Source Type: research
Pulmonary Ionocytes Regulate Airway Surface Liquid pH in Primary Human Bronchial Epithelial Cells
Conclusions: We conclude that ionocytes do not contribute to ASL formation but regulate ASL pH. Club cells secrete the bulk of airway fluid. In CF, abnormal ionocyte and club cell function results in acidic and dehydrated ASL, causing reduced antimicrobial properties and mucociliary clearance. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).PMID:38573173 | DOI:10.1164/rccm.202309-1565OC (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 4, 2024 Category: Intensive Care Authors: Xiaojie Luan Nicolas Henao Romero Veronica A Campanucci Yen Le Jannatul Mustofa Julian S Tam Juan P Ianowski Source Type: research
