Clinical Profile and Treatment of Multiple Myeloma at a Tertiary Hospital in Kenya: A Five-Year Retrospective Review
CONCLUSIONS: MM in KNH is a disease of the middle aged, affecting men and women almost equally and presenting mainly with bone pain and anaemia. Although there seems to be a general improvement in diagnosis and care, access to novel and less toxic agents for treatment is still wanting.PMID:38375211 | PMC:PMC10876299 | DOI:10.1155/2024/3208717 (Source: Advances in Hematology)
Source: Advances in Hematology - February 20, 2024 Category: Hematology Authors: Wanjiku Gichuru Nicholas A O Abinya Andrew Odhiambo Fredrick C F Otieno Simon Harrison Matilda Ong'ondi Source Type: research

An Approach to the Investigation of Thrombocytosis: Differentiating between Essential Thrombocythemia and Secondary Thrombocytosis
CONCLUSION: A practical approach to investigating patients with persistent thrombocytosis based on clinical characteristics such as active malignancy, chronic inflammatory disease, splenectomy, and iron deficiency may assist in accurately identifying patients more likely to have secondary causes of thrombocytosis and reduce overinvestigation, particularly costly molecular testing.PMID:38375212 | PMC:PMC10876298 | DOI:10.1155/2024/3056216 (Source: Advances in Hematology)
Source: Advances in Hematology - February 20, 2024 Category: Hematology Authors: Ala Almanaseer Benjamin Chin-Yee Jenny Ho Alejandro Lazo-Langner Laila Schenkel Pratibha Bhai Bekim Sadikovic Ian H Chin-Yee Cyrus C Hsia Source Type: research

Clinical Profile and Treatment of Multiple Myeloma at a Tertiary Hospital in Kenya: A Five-Year Retrospective Review
CONCLUSIONS: MM in KNH is a disease of the middle aged, affecting men and women almost equally and presenting mainly with bone pain and anaemia. Although there seems to be a general improvement in diagnosis and care, access to novel and less toxic agents for treatment is still wanting.PMID:38375211 | PMC:PMC10876299 | DOI:10.1155/2024/3208717 (Source: Advances in Hematology)
Source: Advances in Hematology - February 20, 2024 Category: Hematology Authors: Wanjiku Gichuru Nicholas A O Abinya Andrew Odhiambo Fredrick C F Otieno Simon Harrison Matilda Ong'ondi Source Type: research

An Approach to the Investigation of Thrombocytosis: Differentiating between Essential Thrombocythemia and Secondary Thrombocytosis
CONCLUSION: A practical approach to investigating patients with persistent thrombocytosis based on clinical characteristics such as active malignancy, chronic inflammatory disease, splenectomy, and iron deficiency may assist in accurately identifying patients more likely to have secondary causes of thrombocytosis and reduce overinvestigation, particularly costly molecular testing.PMID:38375212 | PMC:PMC10876298 | DOI:10.1155/2024/3056216 (Source: Advances in Hematology)
Source: Advances in Hematology - February 20, 2024 Category: Hematology Authors: Ala Almanaseer Benjamin Chin-Yee Jenny Ho Alejandro Lazo-Langner Laila Schenkel Pratibha Bhai Bekim Sadikovic Ian H Chin-Yee Cyrus C Hsia Source Type: research

Presence and Onset of Chronic Kidney Disease as a Factor Involved in the Poor Prognosis of Patients with Essential Thrombocythemia
Adv Hematol. 2024 Feb 8;2024:9591497. doi: 10.1155/2024/9591497. eCollection 2024.ABSTRACTChronic kidney disease (CKD) is an important risk factor for cardiovascular disease, thrombosis, and all-cause death. However, few studies have examined the association between CKD and the prognosis of patients with essential thrombocythemia (ET). We collected ET patients who met the WHO classification 2017 and performed a retrospective clinical study to clarify the association between the presence and onset of CKD and prognosis. Of 73 patients who met the diagnostic criteria, 21 (28.8%) had CKD at the time of ET diagnosis. The age of...
Source: Advances in Hematology - February 16, 2024 Category: Hematology Authors: Yoshinori Hashimoto Hiromi Omura Takayuki Tanaka Source Type: research

Homozygous Sickle Cell Disease after Age of 40: Follow-Up of a Cohort of 209 Patients in Senegal, West Africa
CONCLUSION: This study shows that homozygous SCD is increasingly becoming an adult disease and that it can be carried into old age in Africa. Advanced age over 40 is marked by an upsurge in chronic complications, making it essential to set up a screening program and to organize multidisciplinary follow-up.PMID:38356903 | PMC:PMC10864044 | DOI:10.1155/2024/7501577 (Source: Advances in Hematology)
Source: Advances in Hematology - February 15, 2024 Category: Hematology Authors: Moussa Seck Maureen Ad éniké Dabo Elimane Seydi Bousso Mohamed Keita Sokhna A ïssatou Touré S érigne Mourtalla Guèye Blaise F élix Faye Fatma Dieng Saliou Diop Source Type: research

Anemia Prevalence and Risk Factors in Two of Ethiopia's Most Anemic Regions among Women: A Cross-Sectional Study
CONCLUSIONS: Finally, the anemia burden was dangerously greater than the national average. The region, usage of contraceptives, being pregnant at the time, ANC follow-up, toilet facilities, parity, and marital status all had a substantial impact on anemia. Therefore, to lessen the prevalence of anemia in certain parts of Ethiopia, public health initiatives that improve maternal health service utilization are required, such as ANC follow-up to minimize parity.PMID:38178972 | PMC:PMC10766469 | DOI:10.1155/2023/2900483 (Source: Advances in Hematology)
Source: Advances in Hematology - January 5, 2024 Category: Hematology Authors: Gebru Gebremeskel Gebrerufael Bsrat Tesfay Hagos Source Type: research

Retrospective Study to Reduce Blood Transfusion Waste in Remote Island Healthcare Settings
CONCLUSION: By changing the blood products stockpiled for transfusion medicine in Tokunoshima, the transfusion disposal rate can be reduced.PMID:38116392 | PMC:PMC10730247 | DOI:10.1155/2023/5549655 (Source: Advances in Hematology)
Source: Advances in Hematology - December 20, 2023 Category: Hematology Authors: Takamitsu Sakamoto Hiroyuki Mizuta Naohisa Niiro Teruyoshi Amagai Source Type: research