Challenges and Outcomes of the First Stem Cell Transplant Program in Tanzania, East Africa
CONCLUSION: Commonalities in the socioeconomic challenges in developing countries can be leveraged to create robust HSCT programs in other developing countries.PMID:38524403 | PMC:PMC10960647 | DOI:10.1155/2024/1937419 (Source: Advances in Hematology)
Source: Advances in Hematology - March 25, 2024 Category: Hematology Authors: Stella Rwezaula Mbonea Yonazi Amey Panchal Ashish Dhoot Jemy Mathew Sonu Tony Sandeep Rao Peter Muhoka Samira Mahfudh Neema Budodi Mabula Kasubi Flora Ndobho Helena Kakumbula Koga Luhulla Linda Kapesa Heri Tungaraza Sarah Nyagabona Agnes Shayo Felister Se Source Type: research

The Association of Anticoagulation Intensity with Outcomes in Hospitalized COVID-19 Patients
Adv Hematol. 2024 Mar 11;2024:8838308. doi: 10.1155/2024/8838308. eCollection 2024.ABSTRACTVenous thromboembolism (VTE) risk is increased in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A key question was whether increased intensity of anticoagulation would help prevent VTE and improve patient outcomes, including transfer to the intensive care unit (ICU) and mortality. At the start of the coronavirus disease-19 (COVID-19) pandemic, our institution, Boston Medical Center, instituted a VTE risk stratification protocol based on patients' initial D-dimer levels, medical history, and pres...
Source: Advances in Hematology - March 19, 2024 Category: Hematology Authors: Rena Zheng Alexandra Solomon Madeline DiLorenzo Iniya Rajendran Joseph Park Vrushali Dhongade Michael A Garcia Robert T Eberhardt John Mark Sloan Janice Weinberg Elizabeth S Klings Source Type: research

The Role of Methylation in Chronic Lymphocytic Leukemia and Its Prognostic and Therapeutic Impacts in the Disease: A Systematic Review
Adv Hematol. 2024 Feb 23;2024:1370364. doi: 10.1155/2024/1370364. eCollection 2024.ABSTRACTEpigenetic regulation has been thoroughly investigated in recent years and has emerged as an important aspect of chronic lymphocytic leukemia (CLL) biology. Characteristic aberrant features such as methylation patterns and global DNA hypomethylation were the early findings of the research during the last decades. The investigation in this field led to the identification of a large number of genes where methylation features correlated with important clinical and laboratory parameters. Gene-specific analyses investigated methylation in...
Source: Advances in Hematology - March 4, 2024 Category: Hematology Authors: Sevastianos Chatzidavid Christina-Nefeli Kontandreopoulou Nefeli Giannakopoulou Panagiotis T Diamantopoulos Christos Stafylidis Marie-Christine Kyrtsonis Maria Dimou Panayiotis Panayiotidis Nora-Athina Viniou Source Type: research