Autophagy and anti-inflammation ameliorate diabetic neuropathy with Rilmenidine
CONCLUSIONS: The findings of this study suggest that Rilmenidine may have therapeutic effects on DNP by modulating antioxidant and autophagic pathways.PMID:38055406 | PMC:PMC10691181 | DOI:10.1590/acb387823 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Mehmet Burak Yal çın Ejder Saylav Bora Adem Çakır Sabiye Akbulut Oytun Erba ş Source Type: research

Public and private fundraising as a tool for professional development: What is fundraising?
Acta Cir Bras. 2023 Dec 1;38:e388123. doi: 10.1590/acb388123. eCollection 2023.NO ABSTRACTPMID:38055407 | PMC:PMC10691176 | DOI:10.1590/acb388123 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Everson Luiz de Almeida Artifon Mariana Gon çalves Magon Marcio Roberto Facanali Junior Edna Frasson de Souza Montero Source Type: research

miR-29c-3p represses the angiogenesis of esophageal squamous cell carcinoma by targeting SERPINH1 to regulate the Wnt signaling pathway
CONCLUSIONS: We confirmed the mechanism that miR-29c-3p targeted SERPINH1, thus regulating angiogenesis in ESCC through the Wnt signaling pathway. It improves the understanding of angiogenesis in ESCC and offers new ideas for the research of ESCC treatment strategies in the future.PMID:38055382 | PMC:PMC10695189 | DOI:10.1590/acb385223 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Desheng Wei Zhifeng Ma Ting Zhu Haiyong Wang Bin Wang Linhai Fu Guangmao Yu Source Type: research

Renal protective effect of ellipticine against streptozotocin induced diabetic nephropathy in rats via suppression of oxidative stress and inflammatory mediator
CONCLUSIONS: Ellipticine could be a renal protective drug via attenuating the inflammatory reaction, fibrosis and oxidative stress in streptozotocin induced rats.PMID:38055383 | PMC:PMC10695187 | DOI:10.1590/acb385623 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Jun Li Yu Xie Jimei Sun Fan Bai Shaik Althaf Hussain Venkata Subba Reddy Gangireddygari Xiaolan Jiang Source Type: research

Are both distinct epithelial and stromal cells molecular analysis from phyllodes tumors versus fibroadenoma components affected in breast fibroepithelial progression?
CONCLUSIONS: Identical TERT mutations from both SC and ES origins might affect the PTs tumorigenesis. Gene expression differences suggest coordinated molecular processes between these components with determinant differences acquired by SC, able to fully distinguish PTs from FAs lesions.PMID:38055384 | PMC:PMC10695188 | DOI:10.1590/acb386823 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Ângela Flavia Logullo Waitzberg Elisa Napolitano E Ferreira Mabel Pinilla Paulo Pineda Andr éa Cristina de Moraes Malinverni Fernando Augusto Soares Dirce Maria Carraro Source Type: research

Comparing financing models for supplementary healthcare in appendectomy: activity-based costing (fee-for-service) vs. diagnosis related group remuneration (bundled payment) - a systematic review and meta-analysis
CONCLUSIONS: This study reveals a potential decrease in the length of stay for appendectomy patients using the DRG approach. However, no significant differences were observed in other outcomes analysis between the two approaches.PMID:38055385 | PMC:PMC10699206 | DOI:10.1590/acb386923 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Andr é de Arimatéia de Souza Lino Jose Arnaldo Shiomi da Cruz Breno Cordeiro Porto Rhuan Pimentel Nogueira Jos é Pinhata Otoch Everson Luiz de Almeida Artifon Source Type: research

Effects of chronic restraint stress in the prostate of prepubertal and adult rats
CONCLUSIONS: The stress stimuli promoted changes in hormonal and morphological parameters in the prostate of adult stressed rats. Prepubertal stressed animals did not presented modifications of prostate morphology.PMID:38055386 | PMC:PMC10695186 | DOI:10.1590/acb387123 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Isabella Mendes Proc ópio Carina Teixeira Ribeiro Roger Gaspar Marchon Waldemar Silva Costa Gabriela Faria Buys-Gon çalves Francisco Jos é Barcellos Sampaio Marco Aur élio Pereira-Sampaio Diogo Benchimol de Souza Source Type: research

Role of temporary arterial occlusion in subarachnoid hemorrhage outcomes: a prospective cohort study
CONCLUSIONS: TAO was associated with IOR and surgical complications, being the latter independent of IOR occurrence. In long-term analysis, neither TAO nor IOR were associated with poor clinical outcomes.PMID:38055387 | PMC:PMC10695185 | DOI:10.1590/acb387923 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Marcia Harumy Yoshikawa N ícollas Nunes Rabelo Jo ão Paulo Mota Telles Leonardo Zumerkorn Pipek Guilherme Bitencourt Barbosa Nat ália Camargo Barbato Ant ônio Carlos Samaia da Silva Coelho Manoel Jacobsen Teixeira Eberval Gadelha Figueiredo Source Type: research

Comparative evaluation of three laparoscopic cholecystectomy techniques in rabbit's model
CONCLUSIONS: LC can be performed using different techniques, although the use of EBVS is highly recommended.PMID:38055391 | PMC:PMC10691173 | DOI:10.1590/acb383523 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Monica Carolina Nery Wittmaack Maria Eduarda Bastos Andrade Moutinho Concei ção Mar ía Camila Maldonado Vera Rachel Inamassu Faccini Guilherme Sembenelli Gabriel Luiz Montanhim Mareliza Possa de Menezes Fabiana Del Lama Rocha Luiz Paulo Nogueira Aires Source Type: research

Treatments of palpebral congenital melanocytic nevus: a systematic review
CONCLUSIONS: Most of the studies showed that surgical procedures (exeresis) are able to treat PCMN in the eyelid. The variability in outcomes emphasizes the importance of further research to better understand the most effective and safe approaches for treating congenital melanocytic nevi.PMID:38055392 | PMC:PMC10691178 | DOI:10.1590/acb384823 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Cristina Pires Camargo Marita Saliba Elio Assaad Saad Milanie Milan Jos é Mauricio Caldera Source Type: research

Emodin inhibits bladder inflammation and fibrosis in mice with interstitial cystitis by regulating JMJD3
CONCLUSIONS: Our study reveals the critical role of emodin-JMJD3 signaling in interstitial cystitis by regulating inflammation, fibrosis, and extracellular matrix deposition in cells and tissues, and these findings provide an avenue for effective treatment of patients with cystitis.PMID:38055393 | PMC:PMC10691180 | DOI:10.1590/acb385123 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Junyu Lai Xing Liu Hongwei Su Yongsheng Zhu Ke Xin Mingwei Huang Songtao Luo Hai Tang Source Type: research

Neuroprotective potential of sevoflurane against isoflurane induced cognitive dysfunction in rats via anti-inflammatory and antioxidant effect
CONCLUSIONS: Sevoflurane exhibited the neuroprotection against the cognitive dysfunction in rats via anti-inflammatory and antioxidant mechanism.PMID:38055394 | PMC:PMC10691189 | DOI:10.1590/acb385523 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Yi Gong Peipei Kang Junhui Wang Yan Chen Zhongliang Wei Source Type: research

Saffron reduces the liver fibrosis in mice by inhibiting the JAK/STAT3 pathway
CONCLUSIONS: Saffron can attenuate liver fibrosis by inhibiting the JAK/STAT3 pathway and the activation of hepatic stellate cell, providing a theoretical basis for the development of new anti-fibrotic drugs.PMID:38055395 | PMC:PMC10691186 | DOI:10.1590/acb385823 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Lijuan Huang Yan Han Zhi Wang Qiao Qiu Sichen Yue Qingmin Zhou Wei Su Jianhui Yan Source Type: research

Study of laser fluorescence spectroscopy in livers of rats with hypothermic ischemia
CONCLUSIONS: Fluorescence spectroscopy proves to be promising for real-time analysis of cellular activity and viability. Metabolic activity was observed in groups of live animals and hypothermically preserved samples, indicating cellular function even under blood deprivation and hypothermic conditions.PMID:38055396 | PMC:PMC10691172 | DOI:10.1590/acb386023 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Allison Takeo Tsuge Jaqueline de Jesus Pereira Jos é Dirceu Vollet-Filho M árcia Saldanha Kubrusly Fl ávio Henrique Ferreira Galvão Orlando Nascimento Ribeiro Camila Rodrigues Moreno Renata Nishiyama Ikegami Eleazar Chaib Orlando de Castro E Silva Source Type: research

WD repeat domain 5 promotes the development of late-onset preeclampsia by activating nuclear factor kappa B
CONCLUSIONS: Our finding provides new insights into the role of WDR5 in late-onset preeclampsia development.PMID:38055397 | PMC:PMC10691187 | DOI:10.1590/acb386223 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Xudong Zhao Fengyun Su Fanhua Kong Juan Su Xiaojing Yang Lei Li Aihua Li Qinwen Li Source Type: research