WD repeat domain 5 promotes the development of late-onset preeclampsia by activating nuclear factor kappa B
CONCLUSIONS: Our finding provides new insights into the role of WDR5 in late-onset preeclampsia development.PMID:38055397 | PMC:PMC10691187 | DOI:10.1590/acb386223 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Xudong Zhao Fengyun Su Fanhua Kong Juan Su Xiaojing Yang Lei Li Aihua Li Qinwen Li Source Type: research

Impact of deep resection of endometriosis in the pelvis on urodynamic parameters
CONCLUSIONS: A significant response in the patient's perception of urinary function was demonstrated after surgery. It is observed that the surgical procedure did not affect the uroflowmetric and cystometric characteristics of the evaluated patients.PMID:38055398 | PMC:PMC10691183 | DOI:10.1590/acb386323 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Jardel Cavalcante de Farias Maria do Desterro Soares Brand ão Nascimento Pl ínio da Cunha Leal Caio M árcio Barros de Oliveira Ed Carlos Rey Moura Source Type: research

Assessment of the need for routine intraoperative cell salvage in liver transplantation
CONCLUSIONS: This study suggests that routine cell salvage is unnecessary for all liver transplantations. The most suitable indication for its use is in patients presenting with portal vein thrombosis and abnormal creatinine levels.PMID:38055399 | PMC:PMC10691182 | DOI:10.1590/acb386423 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Claudianne Maia de Farias Lima Tatyane Oliveira Rebou ças Luciana Maria de Barros Carlos Juliana Bezerra Frota Oliveira Eulene Lima da Silva Jana ína Soares Alves Cl ébia Azevedo de Lima Felipe Pantoja Mesquita Jannison Karly Cavalcante Ribeiro Pedro E Source Type: research

Low-fidelity simulation models in urology resident's microsurgery training
CONCLUSIONS: The low-fidelity simulation was able to guarantee urology residents a solid gain in skills and competencies in microsurgery.PMID:38055400 | PMC:PMC10691177 | DOI:10.1590/acb386523 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Lu ís Otávio Amaral Duarte Pinto Renata Cunha Silva L ívia Guerreiro de Barros Bentes Herick Pampolha Huet de Bacelar K átia Simone Kietzer Source Type: research

Does displacement of lower pole stones during retrograde intrarenal surgery improves stone-free status? A systematic review and meta-analysis
CONCLUSIONS: Displacement of lower pole kidney stones for subsequent lithotripsy brings significant benefits in terms of stone-free rate, with no difference in laser energy usage. However, it results in increased surgical time. Despite these factors, the benefits to patients undergoing the procedure are substantial.PMID:38055401 | PMC:PMC10691198 | DOI:10.1590/acb386623 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Roberto Nogueira Santana Breno Cordeiro Porto Carlo Camargo Passerotti Everson Luiz de Almeida Artifon Jos é Pinhata Otoch Jos é Arnaldo Shiomi da Cruz Source Type: research

Lacticaseibacillus casei decrease long-chain fatty acids and most substances in an experimental model of intestinal mucositis
CONCLUSIONS: L. casei prevented the mucosal damage associated with 5-FU-induced intestinal mucositis reduced long-chain fatty acid levels in the feces.PMID:38055402 | PMC:PMC10691171 | DOI:10.1590/acb386723 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Stphannie Jamyla de Ara újo Barbosa Amanda Silveira da Silva Maisie Mitchele Barbosa Oliveira Susana Barbosa Ribeiro Caroline Addison Carvalho Xavier de Medeiros Leandro de Santis Ferreira Francisco Ayrton Senna Domingos Pinheiro Francisco Canind é de S Source Type: research

Fasudil mediates neuroprotection in ischemia/reperfusion by modulating the ROCK-PPAR α-NOX axis
CONCLUSIONS: In mice, the neuroprotective effect of Fasudil depends on the expression of PPARα induced by ROCK-PPARα-NOX axis-mediated reduction in ROS and associated oxidative damage.PMID:38055403 | PMC:PMC10691184 | DOI:10.1590/acb387023 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Xitong Yang Guangming Wang Source Type: research

Puerarin protects renal ischemia-reperfusion injury in rats through NLRP3/Caspase-1/GSDMD pathway
CONCLUSIONS: Puerarin can inhibit the activation of NLRP3/Caspase-1/GSDMD pathway, inhibit inflammatory response and pyroptosis, and enhance the antioxidant capacity of kidney, thereby protecting renal I/R injury in rats.PMID:38055404 | PMC:PMC10691188 | DOI:10.1590/acb387323 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Kangyu Wang Zhao Tang Shuai Liu Yan Liu Huiqing Zhang Haocheng Zhan Source Type: research

Vasopressin in vasoplegic shock in surgical patients: systematic review and meta-analysis
CONCLUSIONS: Considering the outcomes included in our study, it is worth noting that most studies showed that using vasopressin was safe and can be considered in managing postoperative vasoplegic shock.PMID:38055405 | PMC:PMC10691175 | DOI:10.1590/acb387523 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Ta ís Felix Szeles Juliano Pinheiro de Almeida Jos é Arnaldo Shiomi da Cruz Everson Luiz Almeida Artifon Source Type: research

Autophagy and anti-inflammation ameliorate diabetic neuropathy with Rilmenidine
CONCLUSIONS: The findings of this study suggest that Rilmenidine may have therapeutic effects on DNP by modulating antioxidant and autophagic pathways.PMID:38055406 | PMC:PMC10691181 | DOI:10.1590/acb387823 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Mehmet Burak Yal çın Ejder Saylav Bora Adem Çakır Sabiye Akbulut Oytun Erba ş Source Type: research

Public and private fundraising as a tool for professional development: What is fundraising?
Acta Cir Bras. 2023 Dec 1;38:e388123. doi: 10.1590/acb388123. eCollection 2023.NO ABSTRACTPMID:38055407 | PMC:PMC10691176 | DOI:10.1590/acb388123 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Everson Luiz de Almeida Artifon Mariana Gon çalves Magon Marcio Roberto Facanali Junior Edna Frasson de Souza Montero Source Type: research

miR-29c-3p represses the angiogenesis of esophageal squamous cell carcinoma by targeting SERPINH1 to regulate the Wnt signaling pathway
CONCLUSIONS: We confirmed the mechanism that miR-29c-3p targeted SERPINH1, thus regulating angiogenesis in ESCC through the Wnt signaling pathway. It improves the understanding of angiogenesis in ESCC and offers new ideas for the research of ESCC treatment strategies in the future.PMID:38055382 | PMC:PMC10695189 | DOI:10.1590/acb385223 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Desheng Wei Zhifeng Ma Ting Zhu Haiyong Wang Bin Wang Linhai Fu Guangmao Yu Source Type: research

Renal protective effect of ellipticine against streptozotocin induced diabetic nephropathy in rats via suppression of oxidative stress and inflammatory mediator
CONCLUSIONS: Ellipticine could be a renal protective drug via attenuating the inflammatory reaction, fibrosis and oxidative stress in streptozotocin induced rats.PMID:38055383 | PMC:PMC10695187 | DOI:10.1590/acb385623 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Jun Li Yu Xie Jimei Sun Fan Bai Shaik Althaf Hussain Venkata Subba Reddy Gangireddygari Xiaolan Jiang Source Type: research

Are both distinct epithelial and stromal cells molecular analysis from phyllodes tumors versus fibroadenoma components affected in breast fibroepithelial progression?
CONCLUSIONS: Identical TERT mutations from both SC and ES origins might affect the PTs tumorigenesis. Gene expression differences suggest coordinated molecular processes between these components with determinant differences acquired by SC, able to fully distinguish PTs from FAs lesions.PMID:38055384 | PMC:PMC10695188 | DOI:10.1590/acb386823 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Ângela Flavia Logullo Waitzberg Elisa Napolitano E Ferreira Mabel Pinilla Paulo Pineda Andr éa Cristina de Moraes Malinverni Fernando Augusto Soares Dirce Maria Carraro Source Type: research

Comparing financing models for supplementary healthcare in appendectomy: activity-based costing (fee-for-service) vs. diagnosis related group remuneration (bundled payment) - a systematic review and meta-analysis
CONCLUSIONS: This study reveals a potential decrease in the length of stay for appendectomy patients using the DRG approach. However, no significant differences were observed in other outcomes analysis between the two approaches.PMID:38055385 | PMC:PMC10699206 | DOI:10.1590/acb386923 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Andr é de Arimatéia de Souza Lino Jose Arnaldo Shiomi da Cruz Breno Cordeiro Porto Rhuan Pimentel Nogueira Jos é Pinhata Otoch Everson Luiz de Almeida Artifon Source Type: research