Are both distinct epithelial and stromal cells molecular analysis from phyllodes tumors versus fibroadenoma components affected in breast fibroepithelial progression?

CONCLUSIONS: Identical TERT mutations from both SC and ES origins might affect the PTs tumorigenesis. Gene expression differences suggest coordinated molecular processes between these components with determinant differences acquired by SC, able to fully distinguish PTs from FAs lesions.PMID:38055384 | PMC:PMC10695188 | DOI:10.1590/acb386823

Source: Acta Cirurgica Brasileira - December 6, 2023 Category: Surgery Authors: Ângela Flavia Logullo Waitzberg Elisa Napolitano E Ferreira Mabel Pinilla Paulo Pineda Andr éa Cristina de Moraes Malinverni Fernando Augusto Soares Dirce Maria Carraro Source Type: research