Tirofiban a Better Option for Ischemic Stroke When Lytics and Thrombectomy Aren't?
(MedPage Today) -- PHOENIX -- For acute ischemic stroke patients without thrombolytic or thrombectomy options, tirofiban was better than aspirin alone, the TREND trial showed.
In non-cardioembolic stroke, starting tirofiban within 24 hours of... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 9, 2024 Category: Cardiology Source Type: news
Adding Antithrombotic to tPA Does Not Improve Stroke Outcome Adding Antithrombotic to tPA Does Not Improve Stroke Outcome
Argatroban and eptifibatide were ineffective as adjunctive therapies to thrombolysis in patients with ischemic stroke in the MOST trial.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - February 8, 2024 Category: Neurology Tags: Neurology & Neurosurgery Source Type: news
Fast Stroke Thrombolysis Boosts Impact of Thrombectomy
(MedPage Today) -- PHOENIX -- Sooner is better for intravenous thrombolysis (IVT) given before mechanical thrombectomy for acute ischemic stroke, a meta-analysis of patient-level data from randomized controlled trials showed.
While the overall... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 8, 2024 Category: Cardiology Source Type: news
Adjunctive Thrombolysis Doesn't Boost tPA Benefits
(MedPage Today) -- PHOENIX -- Adjunctive thrombolysis with either argatroban or eptifibatide for acute ischemic stroke did not boost efficacy and contributed to risk, the MOST trial showed.
When given after starting alteplase (Activase) or tenecteplase... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 8, 2024 Category: Cardiology Source Type: news
Corticosteroid Still Doesn't Help After Stroke in the Thrombectomy Era
(MedPage Today) -- PHOENIX -- A short course of low-dose methylprednisolone added to endovascular thrombectomy after acute ischemic stroke did not improve outcomes overall, though there was a lower rate of mortality, the randomized MARVEL trial... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 8, 2024 Category: Neurology Source Type: news
Before Stroke Thrombectomy, Keep the Bed Flat, Trial Says
(MedPage Today) -- PHOENIX -- For large vessel occlusion (LVO) acute ischemic stroke patients planned for mechanical thrombectomy, bed positioning made a big difference in clinical worsening, the ZODIAC trial showed.
Keeping the head of the... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 7, 2024 Category: Cardiology Source Type: news
EVT improves outcomes in stroke patients
Endovascular thrombectomy (EVT) may improve outcomes in stroke patients compared to medical management – importantly, even when imaging suggests varying ranges of brain injury, according to a study published February 7 in JAMA.
In a clinical trial, EVT improved clinical outcomes after 90 days in patients with a wide spectrum of infarct volumes (stroke sizes) assessed either by CT or MRI imaging at baseline, noted a group led by Amrou Sarraj, MD, of Case Western Reserve University in Cleveland, OH.
“EVT treatment effects and outcomes may differ by imaging selection modalities and are not well characterized in patients...
Source: AuntMinnie.com Headlines - February 7, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Interventional Neuroradiology Source Type: news
Ginkgo Injections Tied to Cognitive Recovery Post Stroke Ginkgo Injections Tied to Cognitive Recovery Post Stroke
Biologically active components of Ginkgo biloba given by IV injection for 14 days were associated with improved early cognitive recovery in patients with ischemic stroke.Medscape Medical News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - February 7, 2024 Category: Intensive Care Tags: Cardiology Source Type: news
Triptans Warrant Their Current Contraindication, Analysis Suggests
(MedPage Today) -- An initial triptan prescription was linked with ischemic stroke and myocardial infarction for people with a high-risk cardiovascular profile, a case-crossover study in Denmark found.
Among more than 400,000 people who redeemed... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 6, 2024 Category: Cardiology Source Type: news
EVT appears underused in certain stroke patients
In this study, patients hospitalized with ischemic stroke and cardiac intervention may be less than half as likely to receive EVT as those without cardiac intervention,” the group wrote.
Ultimately, the lower rates of EVT after cardiac intervention seen in the study could be explained by multiple factors: delays in diagnosis, clinician reluctance due to perceived higher procedural risk, or patients being ineligible, the researchers suggested.
They noted that additional studies are needed to explore these issues.
“Given the known benefit of EVT, there is a need to better understand the reasons for lower rates of EVT ...
Source: AuntMinnie.com Headlines - January 30, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Cardiovascular Radiology Neuroradiology Source Type: news
Lesion voxels to lesion networks: the enduring value of the Vietnam Head Injury Study - Howard CW, Ferguson MH, Siddiqi SH, Fox MD.
The Vietnam Head Injury Study has been curated by Dr Jordan Grafman since the 1980s in an effort to study patients with penetrating traumatic brain injuries suffered during the Vietnam War. Unlike many datasets of ischemic stroke lesions, the VHIS collecte... (Source: SafetyLit)
Source: SafetyLit - January 29, 2024 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
How AI can flag critical imaging results for priority review and treatments
This study demonstrates the ability of an FDA-cleared artificial intelligence (AI) decision support tool (e-ASPECTS) to improve the performance of US physicians when deriving the ASPECTS," according to the authors. The study called attention to the impact of AI software on physician performance in ASPECTS scoring. Agreement with a reference standard (expert consensus read with reference to follow-up imaging) was evaluated with and without software support.While the study was supported by Brainomix and had several limitations, consistent improvement was seen in both neurology and neuroradiology-qualified doctors, after a su...
Source: AuntMinnie.com Headlines - January 24, 2024 Category: Radiology Authors: Liz Carey Tags: Improving radiology efficiency and outcomes Source Type: news
High Rate of Rehospitalization After First Ischemic Stroke High Rate of Rehospitalization After First Ischemic Stroke
About 80% of patients hospitalized with a first ischemic stroke require a second hospitalization, new data shows. Cardiovascular and cerebrovascular diagnoses at readmission were most common.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - January 23, 2024 Category: Cardiology Tags: Neurology & Neurosurgery Source Type: news
Allogeneic Stem Cell Therapy Falls Short on Stroke Outcomes
(MedPage Today) -- Bone marrow-derived allogeneic stem cell therapy shortly after ischemic stroke did not improve outcomes at 90 days, a phase II/III randomized clinical trial known as TREASURE found.
The rate of excellent outcomes -- a composite... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - January 17, 2024 Category: Cardiology Source Type: news
Aruna Bio Announces FDA Clearance of IND for Lead Program AB126, Enabling the First Exosome to Enter in Human Clinical Trials for a Neurological Indication
Phase 1b/2a clinical trial in acute ischemic stroke expected to initiate in 1H 2024- -Marks the first IND for Aruna's platform with plans to expand AB126, an unmodified exosome derived from proprietary neural stem cells, to other neurological indications including amyotrophic lateral sclerosis-…#gmp #boston #athens #arunabioinc #fda #ab126 #stevenstice #phd #cns #seansavitzmd (Source: Reuters: Health)
Source: Reuters: Health - January 16, 2024 Category: Consumer Health News Source Type: news
