Conducting a randomised controlled trial of a psychosocial intervention for adolescents with type 1 diabetes during COVID-19: recommendations to overcome the challenges complicated by inconsistent public health guidelines on research
This study addresses the challenges in administering an RCT of a psychosocial intervention in two paediatric outpatient diabetes clinics in Dublin Ireland, including recommendations to overcome these. Recommendations include the following: (1) recognise research as an essential service; (2) hospital management should implement guidelines to ensure a consistent approach to the conduct of research during pandemics; (3) ensure that there is a mechanism for the provision of clear and effective communication before the clinic visit with patients, to reassure them and gain their trust; and (4) trial managers should make time to ...
Source: Trials - April 27, 2022 Category: Research Source Type: clinical trials

Hospital management and 1-year outcome of patients aged 70 years and older with severe covid-19
Conditions:   COVID-19;   Elderly Patient Intervention:   Sponsor:   Centre Hospitalier le Mans Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2022 Category: Research Source Type: clinical trials

INTEnsive care bundle with blood pressure reduction in acute cerebral hemorrhage trial (INTERACT3): study protocol for a pragmatic stepped-wedge cluster-randomized controlled trial
DiscussionAs the largest clinical trial in acute ICH, INTERACT3 is on schedule to provide an assessment of the effectiveness of a widely applicable goal-directed care bundle for a serious condition in which a clearly proven treatment has yet to be established.Trial registrationClinicalTrials.gov NCT03209258. Registered on 1 July 2017. Chinese Trial Registry ChiCTR-IOC-17011787. Registered on 28 June 2017 (Source: Trials)
Source: Trials - December 20, 2021 Category: Research Source Type: clinical trials

Effectiveness of Four Transition Dietary Regimens in the Hospital Management of Children With Kwashiorkor.
Conditions:   Severe Acute Malnutrition;   Kwashiorkor;   Nutritional Edema Interventions:   Dietary Supplement: Standard F100;   Dietary Supplement: Standard F75 + Plumpynut;   Dietary Supplement: Alternative F75 with CMV + Plumpynut;   Dietary Supplement: Alternative F75 without CMV + Plumpynut Sponsors:   University Ghent;   Institut de Recherche en Sciences de la Sante, Burkina Faso;   University Hospital Sourô Sanou of Bobo Dioulasso (Burkina Faso);   Centre Muraz Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 20, 2021 Category: Research Source Type: clinical trials