Defining mechanisms of pathogenesis in cutaneous leishmaniasis to develop new approaches to therapy
IIG Seminar Phil Scott received his Ph.D. from the University of Pennsylvania in 1980 where he studied immunoregulatory mechanisms in experimental cutaneous leishmaniasis, and from there went to Dr. Alan Sher ’ s laboratory at NIH where he defined the role of CD4+ Th1 and Th2 cells in controlling leishmaniasis. He left NIH in 1989 to return to Penn, and rose through the ranks to become Professor of Immunology in 1995. During his time at Penn he served for 12 years as Chair of the Department of Pathobiology in the School of Veterinary Medicine, and is currently Vice Dean for Research& Academic Resources. Dr. Scott ’ s c...
Source: Videocast - All Events - November 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Genetic Basis of Protozoan Pathogan Emergence and Disease
NIH Director's Seminar Dr. Grigg’s research program investigates the emergence and pathogenesis of prevalent zoonoses that infect a broad spectrum of animal and human hosts. His group is particularly focused on the protozoan parasites Toxoplasma, Leishmania, Giardia, and Cryptosporidium. He performs population and molecular genetic analyses, using both forward and reverse genetics, to identify virulence genes that control pathogenesis and perturb immune system homeostasis in animal models of natural infection. Recent work is exploring the extent to which protozoan parasites utilize their sexual cycles to rapidly produce...
Source: Videocast - All Events - March 4, 2014 Category: Journals (General) Tags: Upcoming Events Source Type: video