Study to Evaluate the Effect on Parameters of Systemic Inflammation and Disease Outcomes and Safety of RPH-104 in Subjects With Acute ST-elevation Myocardial Infarction
Condition:   Acute ST Segment Elevation Myocardial Infarction Interventions:   Biological: RPH-104 80 mg;   Drug: Placebo Sponsors:   R-Pharm Overseas, Inc.;   Cromos Pharma, LLC;   DM 365, LLC;   Keystat, LLC Not yet recruiting (Source:
Source: - July 9, 2020 Category: Research Source Type: clinical trials

Everolimus-Eluting Stent Versus Bare-Metal Stent in ST-segment Elevation Myocardial Infarction: 10-year Follow-up of the Multicentre Randomized Controlled EXAMINATION-EXTEND Trial
Conditions:   Myocardial Infarction;   ST Elevation Myocardial Infarction;   Infarction;   Necrosis;   Heart Disease;   Cardiovascular Diseases;   Vascular Diseases Interventions:   Drug: Everolimus Eluting Coronary Stent System;   Device: Cobalt chromium balloon expandable stent (non-drug-eluting stent Arm) Sponsor:   Hospital Clinic of Barcelona Completed (Source:
Source: - July 8, 2020 Category: Research Source Type: clinical trials

Near-infrared Spectroscopy Guided Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction
Conditions:   Myocardial Infarction;   Coronary Artery Disease;   Myocardial Ischemia;   Atherosclerosis;   Lipid-Rich Atherosclerosis of Coronary Artery;   Vascular Diseases;   Infarct Ischemia Interventions:   Device: Near-infrared spectroscopy (NIRS);   Device: Angiography Sponsor:   Odense University Hospital Not yet recruiting (Source:
Source: - July 7, 2020 Category: Research Source Type: clinical trials

Acute Myocardial Infarction Study in Northeastern China
Condition:   Acute Myocardial Infarction Intervention:   Procedure: thrombolysis Sponsors:   Second Hospital of Jilin University;   Yanbian University Hospital;   Dunhua City Hospital in Jilin Province;   Liaoyuan City Central Hospital;   Dongliao People's Hospital;   Songyuan Central Hospital;   Changling People's Hospital;   Siping Central Hospital;   The First People's Hospital of Manchu Autonomous County;   Changchun Center Hos...
Source: - June 30, 2020 Category: Research Source Type: clinical trials

Stunning in Takotsubo Versus Acute Myocardial Infarction
Condition:   Myocardial Stunning Interventions:   Diagnostic Test: Echocardigraphy (ECHO);   Diagnostic Test: Bloodtest Sponsor:   Vastra Gotaland Region Recruiting (Source:
Source: - June 26, 2020 Category: Research Source Type: clinical trials

Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial
This study is a phase II, parallel, 2-arm (1:1 ratio), multi-centre, prospective, randomized, double-blind, placebo controlled trial.ParticipantsMale and female patients aged over 18 years old who are diagnosed with pulmonary infection due to COVID-19, admitted to Intensive Care Unit and requiring mechanical ventilation or ECMO will be enrolled in this trial. Patients will be excluded in cases of pregnancy, severe systemic disease with life expectancy less than 6 months, participation in another trial of an investigational drug or device, corticosteroid and/or sympathomimetic use before initiation of treatment. All data wi...
Source: Trials - June 26, 2020 Category: Research Source Type: clinical trials

Randomised controlled trial comparing efficacy and safety of high versus low Low-Molecular Weight Heparin dosages in hospitalized patients with severe COVID-19 pneumonia and coagulopathy not requiring invasive mechanical ventilation (COVID-19 HD): a structured summary of a study protocol
AbstractObjectivesTo assess whether high doses of Low Molecular Weight Heparin (LMWH) (i.e. Enoxaparin 70 IU/kg twice daily) compared to standard prophylactic dose (i.e., Enoxaparin 4000 IU once day), in hospitalized patients with COVID19 not requiring Invasive Mechanical Ventilation [IMV], are:more effective in preventing clinical worsening, defined as the occurrence of at least one of the following events, whichever comes first:DeathAcute Myocardial Infarction [AMI]Objectively confirmed, symptomatic arterial or venous thromboembolism [TE]Need of either:Continuous Positive Airway Pressure (Cpap) or Non-Invasive Ventilatio...
Source: Trials - June 26, 2020 Category: Research Source Type: clinical trials

The relationship between hyperuricemia and contrast-induced acute kidney injury undergoing primary percutaneous coronary intervention: secondary analysis protocol for the ATTEMPT RESCIND-1 study
This study will determine the predictive value of hyperuricemia for the development of CI-AKI and outcomes in patients with STEMI undergoing pPCI. We predict that hyperuricemia will be associated with a risk of CI-AKI in patients with pPCI. Furthermore, after adjusting for other variables, long-term mortality after pPCI may be higher in those with hyperuricemia than in those with normouricemia. Results of this study may provide scientific evidence for the effect of hyperuricemia on CI-AKI and long-term outcomes, thereby offering the potential possibility of lowering SUA on the development of CI-AKI and outcomes.Trial regis...
Source: Trials - June 24, 2020 Category: Research Source Type: clinical trials

Emotion Regulation Intervention to Sustain Physical Activity in Rural-dwelling Women and Men After Myocardial Infarction
Conditions:   Myocardial Infarction;   Emotions Interventions:   Behavioral: eMotion;   Behavioral: Healthy Living Active Control Sponsors:   Indiana University;   Sigma Theta Tau International Not yet recruiting (Source:
Source: - June 22, 2020 Category: Research Source Type: clinical trials