Recapturing Immune Tolerance to Pegloticase for the Management of Tophaceous Gout
Conditions: Tophaceous Gout; Prior Discontinued Use of Pegloticase Due to Failure Interventions: Drug: Rituximab Sponsors: University of California, Los Angeles Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 29, 2023 Category: Research Source Type: clinical trials
A Study of Recombinant Anti-IL-1 β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gout
Conditions: Acute Gout Interventions: Drug: Recombinant Anti-IL-1 β Humanized Monoclonal Antibody Injection 200 mg; Other: Placebo; Drug: Compound Betamethasone Injection; Other: Placebo Sponsors: Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials
Clinical Study of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults
Conditions: Gout With Hyperuricemia in Adults Interventions: Drug: HR091506 tablets + placebo of febuxostat tablets; Drug: febuxostat tablets + placebo of HR091506 tablets Sponsors: Jiangsu HengRui Medicine Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 18, 2023 Category: Research Source Type: clinical trials
Prednisolone Versus Colchicine for Acute Gout in Primary Care (COPAGO): protocol for a two-arm multicentre, pragmatic, prospective, randomized, double-blind, controlled clinical trial of prednisolone and colchicine for non-inferiority with a parallel group design
DiscussionThis trial will provide evidence on the effectiveness of pain reduction and side effects of colchicine and prednisolone in acute gout in primary care.Trial registrationClinicalTrials.gov Identifier: NCT05698680 first posted on January 26, 2023 (retrospectively registered). URL of trial registry record:https://clinicaltrials.gov/study/NCT05698680 (Source: Trials)
Source: Trials - October 5, 2023 Category: Research Source Type: clinical trials
Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With Hyperuricemia
Conditions: Gout; Hyperuricemia Interventions: Drug: dontinurad; Drug: dotinurad + allopurinol; Drug: allopurinol Sponsor: Urica Therapeutics Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials
Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With Hyperuricemia
Conditions: Gout; Hyperuricemia Interventions: Drug: dontinurad; Drug: dotinurad + allopurinol; Drug: allopurinol Sponsors: Urica Therapeutics Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials
Safety & Efficacy of Genakumab in Patients With Frequent Flares
Condition: Acute Gout Interventions: Drug: genakumab; Drug: placebo for Diprospan; Drug: placebo for genakumab; Drug: Diprospan Sponsor: GeneScience Pharmaceuticals Co., Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 9, 2023 Category: Research Source Type: clinical trials
