Genomic Sequencing for Ill Newborns
The performance of whole-genome sequencing in comparison with targeted genomic testing methods is not well understood. In this podcast, JAMA Associate Editor W. Gregory Feero, MD, PHD, interviews author Jill L. Maron, MD, MPH, of the Women and Infants Hospital of Rhode Island about a study of whole-genome sequencing vs a commercially available targeted genetic testing platform for diagnosing ill neonates with suspected genetic conditions. Related Content: Rapid Whole-Genomic Sequencing and a Targeted Neonatal Gene Panel in Infants With a Suspected Genetic Disorder (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - July 11, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Bempedoic Acid in Statin-Intolerant Patients
Bempedoic acid is an effective option for some statin-intolerant patients with an elevated predicted risk of cardiovascular events. However, as JAMA Executive Editor Gregory Curfman, MD, discusses with editorialist Dhruv S. Kazi, MD, MSc, MS, bempedoic acid should not be considered a substitute for statins, which remain the first-line therapy for primary prevention. Related Content: Bempedoic Acid for Primary Prevention of Cardiovascular Events in Statin-Intolerant Patients Bempedoic Acid for High-Risk Primary Prevention of Cardiovascular Disease (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - July 11, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Bempedoic Acid for CVD Prevention, Cytisinicline for Smoking Cessation, Cushing Syndrome, and more
Editor’s Summary by Kristin Walter, MD, MS, Senior Editor of JAMA, the Journal of the American Medical Association, for the July 11, 2023, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - July 11, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

What are the benefits and harms of different treatments for jellyfish stings?
The Cochrane Pain, Palliative and Supportive Care Group produced more than 300 reviews across a very wide range of topics. These include a review of the treatment of jelly fish stings, which was updated in June 2023. We asked lead author, Richard McGee from the Department of Paediatrics in Gosford Hospital in Australia to tell us more and he used an AI voice from elevenlabs.io to make the recording. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - July 11, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts

JAMA Otolaryngology –Head & Neck Surgery : Size Threshold Surveillance —A Revised Approach to Wait-and-Scan for Vestibular Schwannoma
Interview with Matthew L. Carlson, MD, author of Size Threshold Surveillance—A Revised Approach to Wait-and-Scan for Vestibular Schwannoma. Hosted by Paul C. Bryson, MD, MBA. Related Content: Size Threshold Surveillance—A Revised Approach to Wait-and-Scan for Vestibular Schwannoma (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - July 6, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus Disease in High-Risk Kidney Transplant Recipients
Valganciclovir is standard cytomegalovirus (CMV) prophylaxis in high-risk kidney transplant recipients, but its use is limited by myelosuppression. JAMA Deputy Editor Preeti Malani, MD, MSJ, interviews Ajit Limaye, MD, from the University of Washington, about a multinational randomized trial of letermovir vs valganciclovir for CMV prevention in CMV-negative patients receiving a kidney from a CMV-positive donor. Related Content: Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - July 3, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

CMV Prophylaxis in Kidney Transplant, US Maternal Mortality, Diabetic Foot Ulcers, and more
Editor’s Summary by Anne Rentoumis Cappola, MD, ScM, Associate Editor of JAMA, the Journal of the American Medical Association, for the July 3, 2023, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - July 3, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Talk Evidence - post pandemic pruning, breast cancer screening, and orphan drugs
In this episode of Talk Evidence,  Helen Macdonald, Joe Ross, and Juan Franco are back to update us on what's happening in the world of medical evidence. Firstly, the news about the end of the covid-19 pandemic was trumpeted, but the changes to research funding have been more quite - and the team discuss what this means for ongoing work to understand the effects of covid, but also in terms of preparedness for the next pandemic. Next, breast cancer screening recommendations, in the USA, have been reduced from women over the age of 50, to those over the age of 40. We discuss the modelling study which lead to that recommenda...
Source: The BMJ Podcast - June 30, 2023 Category: General Medicine Authors: BMJ Group Source Type: podcasts

JAMA Otolaryngology –Head & Neck Surgery : The Unrealized Potential of the Reg-ent ENT Clinical Data Registry
Interview with Emily F. Boss, MD, MPH, author of The Unrealized Potential of the Reg-ent ENT Clinical Data Registry. Hosted by Paul C. Bryson, MD, MBA. Related Content: The Unrealized Potential of the Reg-ent ENT Clinical Data Registry (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - June 29, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

JAMA Oncology : US Cancer Mortality Trends Among Hispanic Populations From 1999 to 2020
Interview with Sophia C. Kamran, MD, author of US Cancer Mortality Trends Among Hispanic Populations From 1999 to 2020. Hosted by Jack West, MD. Related Content: US Cancer Mortality Trends Among Hispanic Populations From 1999 to 2020 (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - June 29, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

JAMA Psychiatry : Sequential Adaptive Intervention Strategy Targeting Remission and Functional Recovery in Young People at High Risk of Psychosis
Interview with Patrick D. McGorry, MD, PhD, and Barnaby Nelson, PhD, authors of A Sequential Adaptive Intervention Strategy Targeting Remission and Functional Recovery in Young People at Ultrahigh Risk of Psychosis: The Staged Treatment in Early Psychosis (STEP) Sequential Multiple Assignment Randomized Trial. Hosted by John Torous, MD, MBI. Related Content: A Sequential Adaptive Intervention Strategy Targeting Remission and Functional Recovery in Young People at Ultrahigh Risk of Psychosis (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - June 28, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

The Costs of Quality Reporting
US hospitals report data on numerous quality metrics to government and independent rating organizations, but the cost of doing so is not well known. JAMA Associate Editor Karen E. Joynt Maddox, MD, discusses a new study that examines just how many quality metrics hospitals have to report, and attempts to quantify how much data collection and reporting costs in hours and dollars, with corresponding author Stephen A. Berry MD, PhD, Johns Hopkins University, Baltimore, Maryland. Related Content: The Volume and Cost of Quality Metric Reporting (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - June 27, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

DAPT vs tPA for Minor Stroke, Transgender Identity and Suicide, Screening for Anxiety, and more
Editor’s Summary by Karen E. Lasser, MD, MPH, Senior Editor of JAMA, the Journal of the American Medical Association, for the June 27, 2023, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - June 27, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

USPSTF Recommendations: Screening for Depression and Suicide Risk in Adults, and Screening for Anxiety Disorders in Adults
Interview with Michael Silverstein, MD, MPH, USPSTF chair and coauthor of Screening for Depression and Suicide Risk in Adults, and Screening for Anxiety Disorders in Adults: US Preventive Services Task Force Recommendation Statements. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Anxiety Screening Depression and Suicide Risk Screening Screening for Depression and Suicide Risk in Adults Screening for Anxiety Disorders in Adults Screening for Depression and Suicide Risk in Adults Screening for Anxiety Disorders in Adults Are There Reasons to Fear Anxiety Screening? Reframing the Key Q...
Source: JAMA Author Interviews - June 23, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Cranberries for preventing urinary tract infections
Back in October 1998, we published the first version of the Cochrane review of the effects of cranberry for preventing urinary tract infections. Nearly 25 years on, the fifth update was published in April 2023 and we asked lead author, Gabrielle Williams from University of Sydney in Australia to bring us up to date in this podcast. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - June 23, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts